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Study finds J-shaped association between dietary thiamine intake and worsening mental acuity

There seems to be a J-shaped curve between dietary thiamine (vitamin B1) and worsening mental acuity among cognitively healthy older people, suggests research published in the open access journal General Psychiatry.

20 Feb 2024

Unlocking non-hormonal male contraception with HDAC inhibitors

Surveys show most men in the United States are interested in using male contraceptives, yet their options remain limited to unreliable condoms or invasive vasectomies.

20 Feb 2024

Restoring brain pathways to fight opioid addiction

Medical University of South Carolina scientists report in Neuron that they have uncovered a way to restore an opioid-weakened brain pathway in a preclinical model.

20 Feb 2024

Novel treatment strategy shows promise against common liver cancer in children

Hepatoblastoma (HB) is the most common liver cancer in children. Researchers and physicians in the field are concerned because in the last decade HB has been rising rapidly worldwide and has seen the most rapid increase among all pediatric solid tumors.

20 Feb 2024

Overcoming barriers to eating disorder treatment for low-income patients

Individuals with eating disorders who have low income are frequently misdiagnosed and lack adequate access to appropriate therapy, according to researchers from Weill Cornell Medicine and Columbia University Vagelos College of Physicians and Surgeons.

20 Feb 2024

Women gain more health benefits from exercise than men

Women experience greater health benefits from physical activity than men, suggesting a need to encourage more women to engage in exercise to reduce cardiovascular and all-cause mortality.

20 Feb 2024

Scientists identify new therapeutic approach for combating neurodegenerative diseases

A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases, offering hope of improved treatments for Alzheimer's disease, Parkinson's disease, Vanishing White Matter disease and multiple sclerosis, among others.

20 Feb 2024

Finasteride may offer life-saving benefits beyond hair loss treatment

The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide.

20 Feb 2024

Physical activity counters social isolation's mental toll

Physical activity significantly offsets the negative impact of social isolation on mental health, with neuroimaging showing its potential as a compensatory mechanism for emotional well-being.

20 Feb 2024

Healthy plant-based diets linked to lower risk of obstructive sleep apnea

People who eat a healthy, plant-based diet that is high in vegetables, fruit, whole grains and nuts are less likely to suffer with obstructive sleep apnea (OSA), according to a study published today (Wednesday) in ERJ Open Research.

20 Feb 2024

Ultra-processed foods linked to higher risk of sarcopenia

Study finds a direct correlation between ultra-processed food consumption and increased risk of low muscle mass in adults, suggesting dietary changes could combat sarcopenia.

20 Feb 2024

Early childhood food responsiveness may predict eating disorder symptoms

An enthusiastic response to food in early childhood may be linked to a higher likelihood of experiencing eating disorder symptoms in adolescence, according to a new study led by researchers at UCL and Erasmus University Rotterdam.

20 Feb 2024

Adopting key healthy behaviors reduces risk of irritable bowel syndrome

Adopting a healthy lifestyle is strongly linked to a lower risk of irritable bowel syndrome or IBS for short, finds research published online in the journal Gut.

20 Feb 2024

Functional brain changes linked to depression exposure

Study reveals that exposure to depression correlates with significant functional brain changes, varying by depression definition, without notable structural differences, emphasizing the need for precise diagnostic criteria to enhance treatment outcomes.

20 Feb 2024

Smiling makes people more likely to see happiness in expressionless faces

Smiling for just a split second makes people more likely to see happiness in expressionless faces, new University of Essex research has revealed.

20 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024

Historic DNA analysis identifies Down and Edwards syndromes in ancient humans

By analyzing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.

20 Feb 2024

Aging alters fibroblasts to promote pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

20 Feb 2024