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Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

Exploring neurodevelopmental effects on infants from in-utero exposure to COVID-19

A new study aimed to determine the associations between fetal exposure to maternal SARS-CoV-2 infection, in-utero, and child neurodevelopmental status.

7 Jan 2022

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

The current study was based on merged results using the CDD’s surveillance database coupled with the Vaccine Adverse Event Reporting System (VAERS), along with reports from health departments or physicians to the CDC.

7 Jan 2022

Reinfection with SARS-CoV-2 in children

These findings bear out earlier reports that COVID-19 is less frequent and severe in children than adults.

7 Jan 2022

SARS-CoV-2 Omicron variant leads to widespread escape from neutralizing antibody responses

A new study reported the neutralization of Omicron by a large panel of sera collected from convalescent early pandemic, Alpha, Beta, Gamma and Delta infected individuals, as well as among vaccinees receiving three doses of the Oxford/AstraZeneca (AZD1222) or the Pfizer BioNtech (BNT16b2) vaccines.

7 Jan 2022

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Researchers set up a model that included parameters such as the infectiousness of the individual, and lateral flow testing, in order to assess the effectiveness of test-to-release policies as compared to those with fixed-duration isolation mandates

7 Jan 2022

Study provides deeper insights into familial Alzheimer's disease pathogenesis

Alzheimer's disease (AD) is a progressive neurological disease that causes impairments in memory and cognition. AD is believed to result from the deposition of protein "plaques" consisting of amyloid beta (Aβ) proteins sequentially generated via the enzyme γ-secretase.

7 Jan 2022

Levels of infectious SARS-CoV-2 in vaccinated and unvaccinated individuals

A new study assessed the levels of infectious virus (obtained from the nasopharynx) in vaccinated and unvaccinated individuals.

7 Jan 2022

Researchers isolate Omicron variant, leveling the path to vaccine development and vaccine efficacy studies

Researchers from India have now successfully grown and isolated the Omicron variant from hamsters in vivo with further culturing in the Vero CCL-81 cells in vitro, in a step forward towards testing the effectiveness of existing SARS-CoV-2 vaccines and generation of new Omicron appropriate vaccines.

7 Jan 2022

Epidemic model for estimating relative transmissibility and immune escape of SARS-CoV-2 Omicron variant in South Africa

A new study developed a stochastic, multi-strain, compartmental epidemic model to estimate the relative transmissibility and immune escape capacity of the Omicron variant.

7 Jan 2022

Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

A new study aimed to explore whether there is a way to induce the production of potent neutralizing antibodies capable of neutralizing all SARS-CoV-2 variants - including Omicron.

7 Jan 2022

Additional SARS-CoV-2 vaccine doses elicit robust seroresponse among patients receiving maintenance dialysis

Researchers thus recently published a report wherein they examined the seroresponse to an additional dose of vaccine in patients on maintenance dialysis.

7 Jan 2022

Characteristics of initial hospitalization and readmissions among pediatric patients with COVID-19 in the US

Researchers from various institutions describe the characteristics, costs, and healthcare resource use associated with pediatric COVID-19 patients.

7 Jan 2022

Association of obstructive sleep apnea with hospitalization due to COVID-19

Researchers report that OSA is an independent risk factor for severe COVID-19.

7 Jan 2022

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

In a recently published article in the journal Nano-Micro Letters, scientists have provided an in-depth review on the application and benefits of nanotechnology in the development of coronavirus disease 2019 (COVID-19) vaccines.

7 Jan 2022

SARS-CoV-2 Omicron less pathogenic in hamsters

A new research paper posted as a preprint to the bioRxiv* server attempts to throw some light on this question by studying viral pathogenicity in golden hamsters, a valuable model for severe COVID-19 due to the development of reproducible weight loss and pneumonia after infection with the virus.

6 Jan 2022

SARS-CoV-2 Omicron belongs to new antigenic cluster compared to all other VOCs

Researchers investigate SARS-CoV-2 antigenic drift by evaluating the neutralizing activity of sera from patients infected with all five SARS-CoV-2 VOCs.

6 Jan 2022

Scientists assess effectiveness of neutralizing antibodies against seven SARS-CoV-2 variants, including Omicron

Researchers determine the neutralization potency of serum from COVID-19-recovered patients and double-vaccinated individuals against SARS-CoV-2 variants.

6 Jan 2022

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

6 Jan 2022

Antibody binding response significantly reduced for Omicron compared to other SARS-CoV-2 variants

Researchers analyzed ACE2-binding inhibition and antibody binding for the SARS-CoV-2 Omicron variants in individuals with varying levels of immunity.

6 Jan 2022

Medical Science News

Researchers investigate SARS-CoV-2 specific inflammatory response

Exploring neurodevelopmental effects on infants from in-utero exposure to COVID-19

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

Reinfection with SARS-CoV-2 in children

SARS-CoV-2 Omicron variant leads to widespread escape from neutralizing antibody responses

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Study provides deeper insights into familial Alzheimer's disease pathogenesis

Levels of infectious SARS-CoV-2 in vaccinated and unvaccinated individuals

Researchers isolate Omicron variant, leveling the path to vaccine development and vaccine efficacy studies

Epidemic model for estimating relative transmissibility and immune escape of SARS-CoV-2 Omicron variant in South Africa

Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

Additional SARS-CoV-2 vaccine doses elicit robust seroresponse among patients receiving maintenance dialysis

Characteristics of initial hospitalization and readmissions among pediatric patients with COVID-19 in the US

Association of obstructive sleep apnea with hospitalization due to COVID-19

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

SARS-CoV-2 Omicron less pathogenic in hamsters

SARS-CoV-2 Omicron belongs to new antigenic cluster compared to all other VOCs

Scientists assess effectiveness of neutralizing antibodies against seven SARS-CoV-2 variants, including Omicron

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

Antibody binding response significantly reduced for Omicron compared to other SARS-CoV-2 variants

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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