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New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

In a recent research paper currently available on bioRxiv* preprint server, scientists from the University of Oxford in the United Kingdom and the University of Auckland in New Zealand identified several structural specificities of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may serve as viable starting points for the development and optimization of viral inhibitors against coronavirus disease 2019 (COVID-19) and other future threats.

16 Mar 2022

Within-host mathematical model provides insight into dynamics of SARS-CoV-2 infection

Researchers used a within-host mathematical model to determine the dynamics of viral RNA and infectious virus titers in both aerosols and the URT.

15 Mar 2022

Discovery of key brain pathway offers potential new drug target for treating anxiety

A new target in the brain which underpins the eliciting of anxiety and fear behaviors such as 'freezing' has been identified by neuroscientists.

15 Mar 2022

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers evaluate the feasibility of tonsil epithelial cell-derived organoids as an ex vivo model for studying SARS-CoV-2 infection.

15 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Study reveals the oncometabolite role of progesterone in advanced prostate cancer

In a study published in Cell Reports Medicine, a group of Chinese scientists revealed the oncometabolite role of progesterone in advanced prostate cancer and strategies to eliminate its oncogenic effect as an aspect of prostate cancer treatment.

15 Mar 2022

Brain scans show differences in gray matter density in young children with binge eating disorder

Brain scans of children ages 9-10 with a type of eating disorder that causes uncontrollable overeating showed differences in gray matter density compared to their unaffected peers, according to a USC-led study.

15 Mar 2022

Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

A synthetic viral vector and a novel surgical approach developed at Mass Eye and Ear has enabled efficient gene transfer into the inner ear of nonhuman primates, a research team working towards the development of effective treatments for hearing loss and vestibular disorders has reported.

15 Mar 2022

Spray-on technology using customized gold nanoparticles could help treat heart disease

Could a spritz of super-tiny particles of gold and peptides on a damaged heart potentially provide minimally invasive, on-the-spot repair?

15 Mar 2022

New way to deliver potential HIV vaccine using mRNA technology

Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.

15 Mar 2022

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study led by Johns Hopkins Kimmel Cancer Center researchers suggests.

15 Mar 2022

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

The diagnosis of Parkinson's disease (PD) is currently based on consensus clinical criteria. A novel study reported in the Journal of Parkinson's Disease has found that the presence of neuronal deposits of the biomarker phosphorylated alpha-synuclein (p-syn) in the brain and the skin of patients with PD distinguishes them from individuals with symptoms of parkinsonism due to the accumulation of another protein, tau.

15 Mar 2022

Medical Science News

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

Within-host mathematical model provides insight into dynamics of SARS-CoV-2 infection

Discovery of key brain pathway offers potential new drug target for treating anxiety

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Acacetin shows potency against SARS-CoV-2 spike protein

Study reveals the oncometabolite role of progesterone in advanced prostate cancer

Brain scans show differences in gray matter density in young children with binge eating disorder

Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

Spray-on technology using customized gold nanoparticles could help treat heart disease

New way to deliver potential HIV vaccine using mRNA technology

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

Temporary increase in dopamine levels initiates sleep state transitions

Neuronal subpopulation responds specifically to song

Contact tracing data from the first COVID-19 pandemic wave in Shandong Province, China

Resurging COVID-19 events related to cold-chain food or packaging contamination

Sustainable material-based biosensors for SARS-CoV-2 detection

Study models SARS-CoV-2 M protein monomer and dimer 3D structures

Study results in three new co-amorphous drug systems with great anti-COVID-19 potential

SARS-CoV-2 in diabetes pathogenesis

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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