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Increased levels of dopamine play an important role in transition to REM sleep, mice study suggests

What triggers the mammalian sleep cycle's shift between non-rapid eye movement (NREM) and rapid eye movement (REM) sleep? A new study in mice suggests increased levels of dopamine in a key region of the brain during NREM sleep play an important role in this transition.

3 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

Convalescent plasma therapy shows no significant impact on COVID-19 recovery and outcomes

Researchers conduct a multi-center study involving hospitalized COVID-19 patients to gather information on the rationale use of convalescent plasma.

3 Mar 2022

Study provides insight into what causes therapy failure in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Researchers assess the efficacy of 8G3, a B-cell neutralizing antibody against SARS-CoV-2 variants, including the most recent Omicron variant.

3 Mar 2022

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

A new study assesses breakthrough SARS-CoV-2 infections in vaccinated CLD patients with cirrhosis as compared to CLD patients without cirrhosis.

3 Mar 2022

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

A new study has focused on developing a novel anti-SARS-CoV-2 therapy using HTA directed against the human host DEAD-box RNA helicase.

3 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

$The benefits of using fractional doses of COVID-19 vaccines$

The benefits of using fractional doses of COVID-19 vaccines

A new study published in PNAS assessed the benefits of using fractional doses for curbing the current COVID-19 pandemic.

3 Mar 2022

Infection with Omicron sub-lineage BA.1 protects from reinfection against BA.2 sub-lineage and vice-versa

Researchers found that infection with one Omicron sub-lineage of SARS-CoV-2 induces strong protection against reinfection with the other Omicron sub-lineage.

3 Mar 2022

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

In a new study, researchers presented the Multiscale potential of heat-diffusion for affinity-based trajectory embedding approach that identified multimodal signatures of SARS-CoV-2shut.

3 Mar 2022

Identifying and managing drug-drug interactions key to the safe use of nirmatrelvir–ritonavir in COVID-19 treatment

Researchers compiled evidence-based recommendations in consultation with European and North American clinicians and pharmacologists for recognizing and managing drug-drug interactions with nirmatrelvir–ritonavir.

3 Mar 2022

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations of current breast cancer models. These models often fail to mimic complex interactions between cancer cells and key immune cells present in the tumor microenvironment.

3 Mar 2022

Medical Science News

Increased levels of dopamine play an important role in transition to REM sleep, mice study suggests

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Convalescent plasma therapy shows no significant impact on COVID-19 recovery and outcomes

Study provides insight into what causes therapy failure in patients with myelodysplastic syndromes

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

The benefits of using fractional doses of COVID-19 vaccines

Infection with Omicron sub-lineage BA.1 protects from reinfection against BA.2 sub-lineage and vice-versa

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

Identifying and managing drug-drug interactions key to the safe use of nirmatrelvir–ritonavir in COVID-19 treatment

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A model for predicting the evolution of the Omicron wave

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

Study finds new benchmark for measuring the risk of death from heart surgery

Novel MRI approach can identify brain cell damage in people at early stages of Alzheimer's

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Equine hepatitis viruses help gain new insights into the behavior of hepatitis C virus in humans

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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