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QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

The Omicron variant of SARS-CoV-2 may be significantly better than previous variants at evading vaccine-induced antibodies, according to new research from Cambridge - but preliminary evidence suggests it is less likely to cause severe COVID-19 illness in the lungs.

20 Dec 2021

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Researchers discuss the likely impact on current convalescent therapies and immunity of vaccinated individuals against the SARS-CoV-2 Omicron variant.

20 Dec 2021

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Researchers study influenza and SARS-CoV-2 infection models to identify lung memory B cells during viral infection.

20 Dec 2021

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Researchers conduct a comprehensive in vitro analysis of relatively unexplored host immune responses during SARS-CoV-2 infection.

20 Dec 2021

White-tailed deer are efficient carriers of SARS-CoV-2

Researchers demonstrate the susceptibility of white-tailed deer to SARS-CoV-2.

20 Dec 2021

Study identifies genetic causes of sudden unexplained deaths in children aged 1 year and older

A new study found that changes in specific genes may contribute each year to the roughly 400 sudden unexplained deaths in children (SUDC) aged 1 year and older—and separately from sudden infant death syndrome (SIDS).

20 Dec 2021

Genomic study of furin cleavage sites validates the natural evolutionary origin of SARS-CoV-2 in bats

A team of researchers describes the genomic region encompassing the furin cleavage site in SARS-CoV-2.

20 Dec 2021

Dreaded microbe can silence multiple types of pain, study suggests

Anthrax has a scary reputation. Widely known to cause serious lung infections in humans and unsightly, albeit painless, skin lesions in livestock and people, the anthrax bacterium has even been used as a weapon of terror.

20 Dec 2021

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

A new study indicates that as a result of SARS-CoV-2 infection comprehensive changes in protein processing and regulation occur.

20 Dec 2021

COVID-19 infection during pregnancy found to impact infant neurodevelopment

New research suggests that prenatal coronavirus disease 2019 (COVID-19) exposure increases the risk for neurodevelopmental disorders in the baby’s first year of life.

20 Dec 2021

Cloth facemasks worn during exercise are unlikely to cause significant respiratory changes

A new study explored whether wearing masks either increased, reduced, or did not alter various respiratory variables.

20 Dec 2021

Computational analysis of the effect of SARS-CoV-2 Omicron variant spike protein mutations

A new study highlights the potential evolutionary trade-off observed in the omicron variant, detailing the dynamics of the protein structure, its interactions, and subsequent effects.

20 Dec 2021

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

A new study expands the understanding of the impact of receiving a prophylactic monoclonal antibody infusion, as well as other variables, on the endogenous immune response to complete COVID-19 immunization.

20 Dec 2021

Study suggests SARS-CoV-2 Omicron variant RBM binding may be weaker than in wild-type

A new study shows that the Omicron variant binds to the ACE2 receptor in a significantly weaker manner than other variants and the wild-type.

20 Dec 2021

Impact of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military personnel

A new study helps to explain the rapid spread of the Delta variant and provides the impetus to increase control measures including vaccine boosters and social distancing requirements.

20 Dec 2021

Humanized mice reveals why few COVID-19 cases are more severe than others

Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms?

20 Dec 2021

Environmental microbiome's impact on COVID-19 mortality

A new study published on the medRxiv* preprint server was based on the hypothesis that the environmental mycobiome (fungi) is a likely important factor in determining area-level variation in COVID-19 mortality.

19 Dec 2021

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Production of functional SARS-CoV-2 spike protein in single-cell green alga

A new study uses a novel algal platform for the generation of the SARS-CoV-2 spike protein.

19 Dec 2021

Medical Science News

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

White-tailed deer are efficient carriers of SARS-CoV-2

Study identifies genetic causes of sudden unexplained deaths in children aged 1 year and older

Genomic study of furin cleavage sites validates the natural evolutionary origin of SARS-CoV-2 in bats

Dreaded microbe can silence multiple types of pain, study suggests

SARS-CoV-2 infection leads to distinct changes in proteomic and peptidomic profiles and posttranslational modifications

COVID-19 infection during pregnancy found to impact infant neurodevelopment

Cloth facemasks worn during exercise are unlikely to cause significant respiratory changes

Computational analysis of the effect of SARS-CoV-2 Omicron variant spike protein mutations

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

Study suggests SARS-CoV-2 Omicron variant RBM binding may be weaker than in wild-type

Impact of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military personnel

Humanized mice reveals why few COVID-19 cases are more severe than others

Environmental microbiome's impact on COVID-19 mortality

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Production of functional SARS-CoV-2 spike protein in single-cell green alga

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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