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Mutational landscape of SARS-CoV-2 Omicron variant

New research suggests mutations on the receptor-binding domain of the Omicron variant exert indirect effects that reduce antibody binding to epitopes and promote immune evasion.

10 Dec 2021

Impact of mRNA-1273 vaccination during early pregnancy

Researchers from Yale University School of Medicine found that vaccination during the first trimester does not produce congenital disabilities or size abnormalities.

10 Dec 2021

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Researchers have screened several compounds that could show the ability to inhibit SARS-CoV-2.

10 Dec 2021

Research suggests targeting fusion peptide-calcium interaction may help treat COVID-19

Researchers discovered that the entry of coronaviruses is a Ca2+-dependent process and focused their studies on the SARS-1 FP-Ca2+ interaction and its effect on membranes using electron spin resonance (ESR).

10 Dec 2021

Distinct plasma proteins linked to presence and course of COVID-19

In a study published in Viruses, researchers have examined the difference in protein levels in COVID-19 patients.

10 Dec 2021

Study finds sarbecoviruses circulating in wildlife outside Asia can infect human cells

A recent study tested the RBD of 2 sarbecoviruses found in Russian horseshoe bats and other clades 3 viruses for their ability to invade the human cell.

10 Dec 2021

Maternal and neonatal cord-blood antibody profile in response to SARS-CoV-2

The goal of the current research was to determine the profile and specificity of maternal serum and neonatal cord blood antibody responses to SARS-CoV-2 virus exposure in mothers.

10 Dec 2021

Neutralizing antibody response against SARS-CoV-2 variants in health care workers pre- and post-vaccination

Researchers examined neutralizing antibody levels in 48 vaccinated health care workers against the major SARS-CoV-2 variants.

10 Dec 2021

Symptoms after a third mRNA vaccine among patients with inflammatory bowel disease

Researchers published a report wherein they assessed the symptomology post a booster dose of mRNA vaccines in adults with IBD.

10 Dec 2021

Researchers explore role of FTO gene in the comorbidity of depression and obesity

Scientists from the University of Granada (UGR) have highlighted that the possible role attributed to the 'fat mass and obesity-associated' (FTO) gene in the comorbidity of depression and obesity can only be confirmed by conducting more studies involving individuals suffering from both diseases, together with more in-depth analysis of the different clinical subtypes of depression, as some are more prone to being accompanied by obesity than others.

9 Dec 2021

Booster vaccination can reduce breakthrough infection risk in HIV patients

New study reveals that people with HIV are at a high risk of breakthrough COVID-19 infection in comparison to people without HIV, and that booster vaccinations can be protective for those living with HIV.

9 Dec 2021

Study identifies the role of early developmental gene in intracranial aneurysms

Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine.

9 Dec 2021

Assessing the risk of Omicron variant transmission by travelers from South Africa

A new study led by a multinational team of researchers studied the risk of importation of the Omicron variant by travelers from South Africa.

9 Dec 2021

SARS-CoV-2 Omicron variant may bind with ACE2 receptor more efficiently

A new study discusses the effect of the Omicron variant’s mutations on its binding efficiency to the ACE2 receptor.

9 Dec 2021

Study could aid in the development of adaptive DBS treatments for obsessive-compulsive disorder

In a small study, researchers funded by the National Institutes of Health captured more than 1,000 hours of brain recordings from patients with OCD in the clinic and at home.

9 Dec 2021

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective COVID-19 vaccines—shows promise in mice and non-human primates, according to scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

9 Dec 2021

Medical Science News

Mutational landscape of SARS-CoV-2 Omicron variant

Impact of mRNA-1273 vaccination during early pregnancy

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Research suggests targeting fusion peptide-calcium interaction may help treat COVID-19

Distinct plasma proteins linked to presence and course of COVID-19

Study finds sarbecoviruses circulating in wildlife outside Asia can infect human cells

Maternal and neonatal cord-blood antibody profile in response to SARS-CoV-2

Neutralizing antibody response against SARS-CoV-2 variants in health care workers pre- and post-vaccination

Symptoms after a third mRNA vaccine among patients with inflammatory bowel disease

Researchers explore role of FTO gene in the comorbidity of depression and obesity

Booster vaccination can reduce breakthrough infection risk in HIV patients

Study identifies the role of early developmental gene in intracranial aneurysms

Assessing the risk of Omicron variant transmission by travelers from South Africa

SARS-CoV-2 Omicron variant may bind with ACE2 receptor more efficiently

Study could aid in the development of adaptive DBS treatments for obsessive-compulsive disorder

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

Long term vaccine response following Pfizer COVID-19 vaccination in hemodialysis patients

Characterization of SARS-CoV-2 spike protein mutation with no associated increase in epidemiological fitness

Evolution of the SARS-CoV-2 omicron variant

Challenges of bereavement during the COVID-19 pandemic

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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