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SARS-CoV-2 antibody profiles in vaccinated and convalescent macaques compared to humans

New findings suggest that Macaque monkeys may not be the ideal model when testing for SARS-CoV-2.

8 Dec 2021

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

A team of researchers set out to build a full-length, membrane-embedded spike to study its conformational dynamics at the atomic level using molecular dynamics simulations to understand better how this important component of the virus machinery works.

8 Dec 2021

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

New study demonstrates that it is possible one day that breastmilk samples will be used to characterize broad mucosal immunity after vaccination.

8 Dec 2021

Impact of COVID-19 on children with complex underlying medical conditions

A new study concludes that children with medical complexities experienced adverse health outcomes during the COVID-19 pandemic.

8 Dec 2021

Optimizing the treatment of epilepsy patients

Researchers have devised a new diagnostic model to predict how generalized epilepsy patients will respond to drug treatment.

8 Dec 2021

Estimating transmission heterogeneity dynamics of SARS-CoV-2 in Massachusetts

Researchers propose an analytical framework and two methodologies for estimating transmission heterogeneity dynamics in this paper.

8 Dec 2021

Brain injury markers associated with dysregulated immunological responses in COVID-19

Study shows that during hospitalization, patients with COVID-19 demonstrated elevated NfL and GFAP in a severity-dependant manner, as well as evidence of ongoing active brain injury 4 months later.

8 Dec 2021

Quantum mechanical characterization of SARS-CoV-2 Omicron variant interaction with human ACE2 receptor

Researchers from Universite Grenoble Alpes have been investigating the changes in the Omicron variant RBD and how they affect ACE2 binding.

8 Dec 2021

Computational comparison of SARS-CoV-2 Delta and Omicron variant binding affinity with ACE2

Researchers from the Management and Science University in Malaysia have used computational tools to investigate the new variant.

8 Dec 2021

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

A new study has focussed on determining the levels of nAb in individuals who received the second and third doses of the RNA vaccines developed by Pfizer and Moderna.

8 Dec 2021

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

New findings have important implications for research into the impact of COVID-19 and the mRNA vaccination on epigenetic aging in the immune system.

7 Dec 2021

ORF10 protein mutations alter SARS-CoV-2 pathogenicity

Researchers examine 140 unique SARS-CoV-2 ORF10 sequences among 202,968 ORF10 retrieved sequences.

7 Dec 2021

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

New research reports 4’-Fluorouridine (4′-FlU) as an oral antiviral against RSV and SARS-CoV-2.

7 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Risk assessment of the threat of SARS-CoV-2 on banknotes

A new study evaluates the risk of SARS-CoV-2 exposure by fomite transmission during cash transactions.

7 Dec 2021

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

Scientists develop an improved biosensor with Cas12a-based CRISPR on-site rapid detection system and discuss its ability to detect SARS-CoV-2 VOCs.

7 Dec 2021

Delays in hospitals' cardiac care services mount during COVID-19 pandemic

Researchers analyzed 94 papers related to the delivery of healthcare services during the COVID-19 pandemic.

7 Dec 2021

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Researchers investigate the conformational dynamics of the SARS-CoV-2 RBD using the atomistic molecular dynamics simulation method.

7 Dec 2021

Delta SARS-CoV-2 variant drove increase in infection numbers in the U.K.

Researchers determine how different the SARS-CoV-2 Delta variant was from the previously dominant Alpha variant.

7 Dec 2021

Antibody response to COVID-19 vaccine may be affected by the body’s circadian rhythms

Our internal 24-hour circadian clock regulates many aspects of physiology, including the response to infectious disease and vaccination.

7 Dec 2021

Medical Science News

SARS-CoV-2 antibody profiles in vaccinated and convalescent macaques compared to humans

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

Impact of COVID-19 on children with complex underlying medical conditions

Optimizing the treatment of epilepsy patients

Estimating transmission heterogeneity dynamics of SARS-CoV-2 in Massachusetts

Brain injury markers associated with dysregulated immunological responses in COVID-19

Quantum mechanical characterization of SARS-CoV-2 Omicron variant interaction with human ACE2 receptor

Computational comparison of SARS-CoV-2 Delta and Omicron variant binding affinity with ACE2

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

ORF10 protein mutations alter SARS-CoV-2 pathogenicity

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Risk assessment of the threat of SARS-CoV-2 on banknotes

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

Delays in hospitals' cardiac care services mount during COVID-19 pandemic

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Delta SARS-CoV-2 variant drove increase in infection numbers in the U.K.

Antibody response to COVID-19 vaccine may be affected by the body’s circadian rhythms

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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