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HPV16 vaccine shows promise in treating precancerous cervical lesions

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

24 Jan 2025

Volunteering reduces loneliness in older adults

Researchers examine how social volunteering affects the social and emotional aspects of loneliness among older adults in China.

24 Jan 2025

Study reveals sex-specific differences in microglial response to CSF1R inhibition

Researchers investigate the sex-dependent microglial response to a colony-stimulating factor 1 receptor (CSF1R) inhibitor.

24 Jan 2025

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

Researchers uncover how slow CAG repeat expansions in neurons drive Huntington’s disease over decades.

24 Jan 2025

Study finds successful treatment of childhood obesity lowers long-term health risks

Effective treatment of childhood obesity significantly lowers long-term health risks, including type 2 diabetes and hypertension, promoting better adult health.

24 Jan 2025

A global look at the gut: Scientists highlight microbiome diversity

Researchers analyzed 168,464 samples to uncover how geographic and technical factors shape global gut microbiome variation, highlighting underrepresented regions and technical biases.

23 Jan 2025

Study shows how physical activity can enhance brain function and prevent dementia

A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function.

23 Jan 2025

New compound V-161 offers hope in the fight against antibiotic-resistant bacteria

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.

23 Jan 2025

Lean red meat in balanced diet supports gut and heart health, study reveals

A recent study from Purdue University scientists reveals following a consistent dietary pattern that features lean red meat can contribute to gut microbiota balance and support cardiovascular health.

23 Jan 2025

New discovery sheds light on how bacteria use plasmids to build resistance

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs.

23 Jan 2025

Researchers identify ferroptosis as driver of osteocyte death in melanoma metastasis

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

23 Jan 2025

Understanding the long-term effects of repetitive head hits in athletes

The impact makes us cringe-the sound of two helmets making contact during a football game, a player down on the field.

23 Jan 2025

New $20 million NIH grant aims to uncover the secrets of the human virome

Unlocking knowledge about the vast and varied collection of viruses that live in and on our bodies is the goal of a $20 million grant from the Common Fund of the National Institutes of Health (NIH) to researchers, including a team at UTHealth Houston.

23 Jan 2025

Crick researchers identify key Y chromosome genes influencing sperm development

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice.

23 Jan 2025

Boosting BCL6 may counteract muscle loss from GLP-1 medications

About one in eight adults in the United States has tried or currently uses a GLP-1 medication, and a quarter of those users cite weight loss as their main goal.

23 Jan 2025

New approach to treating ependymoma with leukemia drug

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk Cook Professor of Radiation Oncology at Harvard Medical School, is senior author of a new study in PNAS, Targeting EPHB2/ABL1 Restores Anti-Tumor Immunity in Preclinical Models of Ependymoma.

23 Jan 2025