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Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs called immune checkpoint inhibitors, according to findings published in Science Translational Medicine.

24 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Study finds rhinovirus reduces SARS-CoV-2 replication in airway epithelial cells

A recent study has demonstrated that SARS-CoV-2 infection induces a significantly lower interferon response than rhinovirus infection.

24 Nov 2021

Exosomes involved in the progression of breast cancer in patients with obesity, diabetes

Obesity, insulin resistance and Type 2 diabetes are risk factors for breast cancer in post-menopausal women. The metabolic and inflammatory complications of obesity have a role in the formation of cancer.

24 Nov 2021

Healthcare workers at increased SARS-CoV-2 infection risk during second wave

A new study evaluates the SARS-CoV-2 infection rates among healthcare workers during the second wave of the COVID-19 pandemic.

24 Nov 2021

Antibody persistence in infants after maternal COVID-19 vaccination

New research finds COVID-19 vaccination during pregnancy results in significantly greater antibody persistence in the infants compared to natural infection of the mothers during pregnancy.

24 Nov 2021

How does penicillin work?

In this interview, we spoke to Dr. Bartlomiej Salamaga about his latest research that discovered how penicillin works in the body.

24 Nov 2021

Bat coronavirus ecology, evolution, and spillover

In a review published in Nature Reviews Microbiology, the authors collate information about the ecology and evolution of bat coronaviruses.

24 Nov 2021

Markers of SARS-CoV-2 shedding in vaccinated and unvaccinated individuals

The study uses serial mid-turbinate nasal specimens collected from a subset of incarcerated persons infected during this outbreak.

24 Nov 2021

Spread and evolution of SARS-CoV-2 lineages with possible recombination events

Researchers examined the dissemination and evolution of four SARS-CoV-2 lineages as well as the potential that one or more recombination events played a role in their evolution.

24 Nov 2021

Estimation of the SARS-CoV-2 infectious period

A new study focused on estimating the temporal dynamics of transmissibility of infected cases in the absence of intervention measures (unmitigated generation interval).

24 Nov 2021

Vaccine-induced immune responses for SARS-CoV-2 in patients receiving anti-CD20 B-cell depleting therapies

A new study published on the medRxiv* preprint server analyzed the trajectories of anti-SARS-CoV-2 antibodies in patients from the RituxiVac study were compared to healthy volunteers. In addition, they investigated the immunogenicity of a third vaccine dose in previously non-responding patients.

23 Nov 2021

New therapeutic approach prevents growth of metastatic tumors by putting cancer cells to sleep

A new therapeutic approach prevents the growth of metastatic tumors in mice by forcing cancer cells into a dormant state in which they are unable to proliferate.

23 Nov 2021

Higher antibody level correlates with greater vaccine protection against COVID-19

By measuring antibodies against the SARS-CoV-2 spike protein in participants in a phase 3 trial of the Moderna COVID-19 vaccine, researchers found that the higher the antibody level, the greater the vaccine protection against COVID-19.

23 Nov 2021

Study explains why moles can change into melanoma

Moles and melanomas are both skin tumors that come from the same cell called melanocytes. The difference is that moles are usually harmless, while melanomas are cancerous and often deadly without treatment.

23 Nov 2021

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

A new study, published on the bioRxiv* preprint server, has discovered a class of new immunostimulatory RNAs while studying influenza infection-associated host genes in human lung epithelial cells using small interfering RNAs (siRNAs). Scientists revealed that these short duplex RNAs could induce type I and type III interferons (IFN-I/III) in a wide variety of cells.

23 Nov 2021

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Researchers at Yale University analyzing specialized MRI exams found significant changes in the microstructure of the brain's white matter in adolescents and young adults with autism spectrum disorder (ASD) compared to a control group, according to research being presented next week at the annual meeting of the Radiological Society of North America.

23 Nov 2021

Medical Science News

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Study finds rhinovirus reduces SARS-CoV-2 replication in airway epithelial cells

Exosomes involved in the progression of breast cancer in patients with obesity, diabetes

Healthcare workers at increased SARS-CoV-2 infection risk during second wave

Antibody persistence in infants after maternal COVID-19 vaccination

How does penicillin work?

Bat coronavirus ecology, evolution, and spillover

Markers of SARS-CoV-2 shedding in vaccinated and unvaccinated individuals

Spread and evolution of SARS-CoV-2 lineages with possible recombination events

Estimation of the SARS-CoV-2 infectious period

Vaccine-induced immune responses for SARS-CoV-2 in patients receiving anti-CD20 B-cell depleting therapies

New therapeutic approach prevents growth of metastatic tumors by putting cancer cells to sleep

Higher antibody level correlates with greater vaccine protection against COVID-19

Study explains why moles can change into melanoma

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Time of starting antiretroviral therapy can influence tumor development In HIV patients

Strong antibody responses against harmless coronaviruses may protect against SARS-CoV-2

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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