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People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors - a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions - generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study by researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

UC researchers engineer new probiotic to target and break down cancer cell defenses

Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways.

21 Nov 2021

Researchers discover new link between diet, intestinal stem cells and disease

The intestine is essential for maintaining our energy balance and is a master at reacting quickly to changes in nutrition and nutrient balance.

21 Nov 2021

New evidence that host immunity drives evolution of the dengue virus

New research by a team of University of Florida investigators, and others, provides evidence that host immunity drives evolution of the dengue virus.

20 Nov 2021

Weill Cornell Medicine receives $1.27 million DoD grant to develop treatment for rare eye condition

Weill Cornell Medicine has received a $1.27 million grant from the United States Department of Defense (DoD) to develop treatment for a rare but devastating eye condition largely affecting military personnel who suffer traumatic eye injuries in combat.

20 Nov 2021

Harvard Chan School and SAHZU announce the launch of bilateral exchange program in clinical research

The Harvard T.H. Chan School of Public Health and Zhejiang University School of Medicine in Hangzhou, China, today announced the launch of a bilateral exchange program in clinical research to enhance the research capabilities of both institutions and to develop a multi-year program of clinical research education.

20 Nov 2021

Neuropharmacologist investigates plant-based treatments for epilepsy caused by pork tapeworms

Pork tapeworms are responsible for between 30 and 70 per cent of epilepsy cases around the world. According to the World Health Organization, the majority of people living with epilepsy can be found in low-income countries, mostly among subsistence farming communities.

19 Nov 2021

Brain stimulation can modulate thought processes related to problem solving

New methods of brain stimulation are being tested to see whether they can be used to enhance cognitive behavior. In this study, researchers from Japan have found that stimulation at specific frequencies can modulate thought processes related to problem solving.

19 Nov 2021

Effectiveness of COVID-19 vaccination during Delta variant predominance

A new study investigated the continued effectiveness of COVID-19 vaccination during the delta variant predominance in a diverse and urban healthcare setting.

19 Nov 2021

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

In a review published in Signal Transduction and Targeted Therapy, researchers from Sichuan University have reviewed the available literature.

19 Nov 2021

World Antimicrobial Awareness Week 2021: An Interview with Pan American Health Organization (PAHO)

For World Antimicrobial Awareness Week (WAAW) 2021, we spoke to Dr. Pilar Ramon Pardo from the Pan American Health Organization.

19 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

COVID-19 induced excess mortality

A new study presented a generalized linear mixed model to determine the rate of mortality related to COVID-19 infection in Lombardy, Italy.

19 Nov 2021

Can you take the COVID-19 and Influenza vaccines on the same day?

Scientists have conducted a substudy within a phase 3 UK trial and have reported the safety, immunogenicity, and efficacy of the NVX-CoV2373 COVID-19 vaccine when co-administered with licensed seasonal influenza vaccines.

19 Nov 2021

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Researchers identified a subset of species in which the threat of spillback infection appears the most significant due to location and increased contact with humans in areas with a high prevalence of SARS-CoV-2.

19 Nov 2021

Viral biomolecular condensation

A review published in PLOS Pathogens deconstructs virus condensation and provides a biochemical background for LLPS.

19 Nov 2021

Study involving a rat model offers potential treatment for Alexander disease

Alexander disease is a progressive and rare neurological disorder with no cure or standard course of treatment. But a new study led by researchers at the University of Wisconsin–Madison involving a rat model of the disease offers a potential treatment for the typically fatal condition.

18 Nov 2021

UCLA-developed new "virtual histology" technology may reduce need for skin biopsies

Instead of surgically removing a sample of skin, sending it to a lab and waiting several days for results, your dermatologist takes pictures of a suspicious-looking lesion and quickly produces a detailed, microscopic image of the skin.

18 Nov 2021

New test enables patient-specific monitoring and treatment for ovarian cancer

Around 870 cases of ovarian cancer are reported in Belgium every year. Most of these patients are treated with surgical interventions and/or chemotherapy.

18 Nov 2021

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

The new research findings help to understand mechanisms that lead to different types of intestinal tumors. They show that the Lef1 gene suppresses the development and growth of colorectal cancer by restricting the formation of cancer stem cell niches.

18 Nov 2021

Medical Science News

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

UC researchers engineer new probiotic to target and break down cancer cell defenses

Researchers discover new link between diet, intestinal stem cells and disease

New evidence that host immunity drives evolution of the dengue virus

Weill Cornell Medicine receives $1.27 million DoD grant to develop treatment for rare eye condition

Harvard Chan School and SAHZU announce the launch of bilateral exchange program in clinical research

Neuropharmacologist investigates plant-based treatments for epilepsy caused by pork tapeworms

Brain stimulation can modulate thought processes related to problem solving

Effectiveness of COVID-19 vaccination during Delta variant predominance

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

World Antimicrobial Awareness Week 2021: An Interview with Pan American Health Organization (PAHO)

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

COVID-19 induced excess mortality

Can you take the COVID-19 and Influenza vaccines on the same day?

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Viral biomolecular condensation

Study involving a rat model offers potential treatment for Alexander disease

UCLA-developed new "virtual histology" technology may reduce need for skin biopsies

New test enables patient-specific monitoring and treatment for ovarian cancer

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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