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E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Researchers look to better understand the molecular basis of E406W-mediated escape from the REGEN-COV cocktail and cilgavimab.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

New atlas characterizes immune cells that play a role in hemorrhagic stroke

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.

28 Jan 2022

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age.

28 Jan 2022

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the retina, leads to an accumulation of ceramides in the retina, resulting in progressive photoreceptor cell death and ultimately vision loss.

28 Jan 2022

Metabolic adaptation increases the length of time to achieve weight-loss goals

In women who are premenopausal with overweight, metabolic adaptation after a 16% weight loss increases the length of time necessary to achieve weight-loss goals, according to a study published online in Obesity, The Obesity Society's flagship journal.

27 Jan 2022

Novel molecular signaling pathway plays a key role in producing osteoarthritis pain

Researchers from North Carolina State University have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain.

27 Jan 2022

Psychedelic analogs show antidepressant-like activity in mice without causing hallucination

Analogs of drugs like psilocybin and LSD show antidepressant-like activity in mice without causing hallucination, researchers report.

27 Jan 2022

Curtailed sleep may increase exercise-induced cardiac strain

In a new study, participants underwent an intense bout of exercise after both normal sleep and after three nights of curtailed sleep.

27 Jan 2022

Northwestern and partners are part of mega NIH program to investigate precision nutrition

Northwestern, the University of Chicago, Illinois Institute of Technology, University of Illinois, Chicago and Rush University are part of a mega National Institutes of Health (NIH) $170 million program that is the first comprehensive study to investigate precision nutrition.

27 Jan 2022

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

Eating more meat, having less of certain bacteria in the gut, and more of certain immune cells in the blood, all link with multiple sclerosis, reports a team of researchers led by UConn Health and Washington University School of Medicine.

27 Jan 2022

Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

In a new study, researchers identified conserved sites in the SARS-CoV-2 spike protein using structural and sequence data, and then combined the results with existing deep mutational scanning data to design six antigens that can offer protection against significant immune escape mutations in the SARS-CoV-2 receptor-binding domain.

27 Jan 2022

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

In a new study, researchers analyzed the effects of multi-nutrient supplementation on SARS-CoV-2 vaccine efficacy and the overall improvement of respiratory and muscle function in elderly COVID-19 patients.

27 Jan 2022

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Researchers show that the CHI3L1 inhibitors reduce epithelial cell infection by SARS-CoV-2 VOC pseudovirus moieties.

27 Jan 2022

Significance of metabolic parameters in COVID-19 prognosis

In a new study, researchers evaluated the significance of metabolic parameters in determining COVID-19 prognosis.

27 Jan 2022

Impact of full vaccination with booster doses during periods of different SARS-CoV-2 variant emergence and dominance in the United States

This study aimed to assess the impact of full vaccination with additional and booster doses.

27 Jan 2022

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

A recent study was published where CFR was assessed for COVID-19 vaccine effectivity

27 Jan 2022

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Researchers have been investigating the phosphorylation of the nucleocapsid protein.

27 Jan 2022

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma.

27 Jan 2022

Smart Tissue Autonomous Robot performs laparoscopic surgery on pig soft tissue without human help

A robot has performed laparoscopic surgery on the soft tissue of a pig without the guiding hand of a human – a significant step in robotics toward fully automated surgery on humans.

27 Jan 2022

Medical Science News

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

New atlas characterizes immune cells that play a role in hemorrhagic stroke

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Metabolic adaptation increases the length of time to achieve weight-loss goals

Novel molecular signaling pathway plays a key role in producing osteoarthritis pain

Psychedelic analogs show antidepressant-like activity in mice without causing hallucination

Curtailed sleep may increase exercise-induced cardiac strain

Northwestern and partners are part of mega NIH program to investigate precision nutrition

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Significance of metabolic parameters in COVID-19 prognosis

Impact of full vaccination with booster doses during periods of different SARS-CoV-2 variant emergence and dominance in the United States

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

Smart Tissue Autonomous Robot performs laparoscopic surgery on pig soft tissue without human help

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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