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Radiation therapy puts childhood cancer survivors at higher risk of cardiometabolic disease

Decades after battling childhood cancer, survivors often face a new challenge: cardiometabolic disease. A spectrum of conditions that includes coronary heart disease and diabetes, cardiometabolic disease typically impacts people who are obese, elderly, or insulin resistant.

9 Nov 2021

COVID-19 and loss of sense of smell

A recent review examines the high susceptibility of the olfactory epithelium to SARS-CoV-2 infection.

9 Nov 2021

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

SARS-CoV-2 infection regulates protein arginylation

A new study explores the role of arginylation during SARS-CoV-2 infection.

9 Nov 2021

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

A biomedical engineering professor at Binghamton University, State University of New York has received a $2.4 million grant to develop a faster, less painful way to diagnose malignant solitary pulmonary nodules (SPNs).

9 Nov 2021

Impact of COVID-19 pandemic on women’s experience of pregnancy in UK

The current study deals with the results of a study carried out on pregnant women.

9 Nov 2021

SARS-CoV-2 infection in white-tailed deer

In the current study, SARS-CoV-2 antibodies were identified in over a third of free-ranging deer in northeast Ohio.

9 Nov 2021

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

The current study looked at the impact of the virus on the CNS in the Syrian golden hamster, a useful animal model for COVID-19.

9 Nov 2021

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Researchers from the University of Toronto set out to create a new tetravalent antibody that could bind with enough potency that it could remain effective against VOCs.

9 Nov 2021

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Researchers from VaxiGen have been investigating the potential for a DNA vaccine boost to VP vaccines against coronavirus disease 2019.

9 Nov 2021

COVID-19 drug candidate with wide-ranging antiviral activity

A new study investigated the antiviral activity and mechanism of action of Brilacidin against multiple human coronaviruses.

9 Nov 2021

Invalidation of potential SARS-CoV-2 protease inhibitors

Researchers identified several structurally disparate compounds that can inhibit the viral protease PLpro and determined whether the identified PLpro inhibitors are truly effective and should be further investigated.

9 Nov 2021

Hiding face movements with a mask can affect our ability to socially interact with others

Study finds blocking or hiding facial movement can affect sharing of emotions and social interaction

9 Nov 2021

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma.

8 Nov 2021

Medical Science News

Radiation therapy puts childhood cancer survivors at higher risk of cardiometabolic disease

COVID-19 and loss of sense of smell

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Targeting Shp2 in oncological treatments appears to worsen the disease

SARS-CoV-2 infection regulates protein arginylation

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

Impact of COVID-19 pandemic on women’s experience of pregnancy in UK

SARS-CoV-2 infection in white-tailed deer

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

COVID-19 drug candidate with wide-ranging antiviral activity

Invalidation of potential SARS-CoV-2 protease inhibitors

Hiding face movements with a mask can affect our ability to socially interact with others

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Inhalation of CO2 after a traumatic experience enhances fear memory in mice

Discovery of potent neutralizing antibodies against SARS-CoV-2 variants

SARS-CoV-2 Nsp1 deletions affect protein stability and translation inhibition

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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