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SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

Study explores sex-driven differences in individualized clinical management of Alzheimer’s disease risk

A new study demonstrated how individualized clinical management of Alzheimer's disease risk was viable in a clinical outpatient setting.

29 Apr 2022

Exploring happy hypoxia in COVID-19 patients

In a new study, researchers reported that silent hypoxia was not unique to COVID-19.

29 Apr 2022

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

A recent article published in the Med journal reported that the SARS-CoV-2 booster vaccinations enhance the SARS-CoV-2 Omicron sublineage neutralizations.

29 Apr 2022

Poor asthma control triggered by SARS-CoV-2

In a new study, researchers noted that COVID-19 could trigger poor pediatric asthma control.

29 Apr 2022

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Researchers surveilled coronaviruses found in bats via targeted genomic sequencing.

29 Apr 2022

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Researchers discussed the validity of the equation derived by Khoury et al. and reported by Muena et al. regarding the immunological correlate of protection to predict the efficacy of new coronavirus vaccines in a real-world setting.

29 Apr 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

In a new study, researchers described their self-designed chimeric receptor-binding domain-dimer vaccine approach to adapt SARS-CoV-2 variants of concern and variants of interest.

29 Apr 2022

Lower COVID-19 mortality among physically active individuals in Sub-Saharan Africa

Researchers enlisted the benefits of physical activity and being outdoors in reducing the incidence, prevalence, and severity of COVID-19 among low-income populations.

29 Apr 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

A recent study demonstrated that the phytochemical curcumin is a potent therapeutic prospect against the SARS-CoV-2 Omicron variant

29 Apr 2022

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

A new study published in Marine Drugs evaluated the inhibitory effect of three polysaccharides, crude polysaccharide from Hizikia fusiforme (CPHF), crude polysaccharide from Sargassum horneri (CPSH), and crude polysaccharide from abalone viscera (CPAV) on the propagation of SARS-CoV-2 in vitro.

28 Apr 2022

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Spinal cord stimulation (SCS) for chronic pain involves delivering low levels of electricity directly into the spinal cord using an implanted device, which modifies or blocks nerve activity to minimize the sensation of pain reaching the brain.

28 Apr 2022

Study offers critical clues into longstanding mystery of deep sleep

Healthy sleep is a basic physiologic need. In its absence, a myriad of processes in the body can go terribly awry. Chronic sleep problems have been linked to mental health disorders, cardiovascular disease, type 2 diabetes, and obesity, among other conditions.

28 Apr 2022

Scientists identify the neural basis of pleasant touch sensation

Studying mice, scientists at Washington University School of Medicine in St. Louis have identified a neural circuit and a neuropeptide - a chemical messenger that carries signals between nerve cells - that transmit the sensation known as pleasant touch from the skin to the brain.

28 Apr 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Medical Science News

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Probenecid shows activity against respiratory syncytial virus

Study explores sex-driven differences in individualized clinical management of Alzheimer’s disease risk

Exploring happy hypoxia in COVID-19 patients

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

Poor asthma control triggered by SARS-CoV-2

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Artificial circular RNAs found to bypass cellular antiviral responses

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

Lower COVID-19 mortality among physically active individuals in Sub-Saharan Africa

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Study offers critical clues into longstanding mystery of deep sleep

Scientists identify the neural basis of pleasant touch sensation

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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