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New technique could allow more diseases to be safely treated by nanomedicine

Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy's effectiveness.

11 Jan 2022

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters "good" macrophage behavior within the vessel wall.

11 Jan 2022

Engineering higher affinity SARS-CoV-2 antibodies

A new study describes the potential of engineered neutralizing antibodies that have a high affinity for the binding epitopes.

11 Jan 2022

Adding a tomato concentrate to the diet can reduce intestinal inflammation related to HIV

New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.

11 Jan 2022

Withdrawing steroid treatment found to boost SARS-CoV-2 vaccine-induced immunity in kidney transplant recipients

In a new study, a team of researchers investigated the impact of the fourth dose of a vaccine against COVID-19 in kidney transplant recipients, who had not mounted a humoral immune response to three doses of vaccine.

11 Jan 2022

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

A recent study discussed the expansion of the SARS-CoV-2 CRISPR-Cas detection technology (SHERLOCK) into Variant-specific SHERLOCK (VarLOCK) assays to accurately differentiate between the newly emerging SARS-CoV-2 variants of concern.

11 Jan 2022

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

In a new study, researchers determined the early immune response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during mild coronavirus disease 2019 (COVID-19) in rhesus macaques.

11 Jan 2022

Exploring the kinetics of SARS-CoV-2 Marseille-4 variant

In a new study, researchers determined the nature and dynamics of mutations associated with the SARS-CoV-2 French Marseille-4 variant during 10 months from its onset, and concluded that the heterogenicity associated with a SARS-CoV-2 lineage can possibly predict the end of an outbreak.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

A new preprint examines the extent of protection offered by T cell responses to primary vaccination and/or natural infection with the virus.

11 Jan 2022

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

In a new study, researchers examined the impact of mutations on the structural thermodynamic stability (structural stability) of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through free energy computation.

11 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

Evaluating effectiveness of the COVID-19 mRNA-1273 vaccine against Omicron and Delta variants

Researchers recently assessed vaccine effectiveness against Omicron and Delta variant-induced infection as well as hospitalization, including among immunocompromised individuals.

11 Jan 2022

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

The current study examines the role of heterologous vaccination, an area that lacks much clarity.

11 Jan 2022

The effect of COVID-19 on routine immunizations for vaccine-preventable diseases

A new study has focussed on determining the impact of COVID-19 associated interferences with different recovery scenarios for ten vaccine-preventable diseases.

11 Jan 2022

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

A team of researchers recently analyzed differential protein glyco-isoform distributions of symptomatic and asymptomatic coronavirus disease 2019 patients.

11 Jan 2022

Dynamics of infectious diseases and restrictions on the size of social gatherings

A new study has been published that used epidemiological theory to elucidate the association between gathering size and general disease dynamics.

11 Jan 2022

Development and validation of 2-gene host-based COVID-19 diagnostic classifiers

A group of researchers from Biohub has been attempting to create a more accurate method for PCR testing.

11 Jan 2022

Real-world effectiveness of three COVID-19 vaccines

Researchers from IQVIA Real-World Solutions have investigated how effective these vaccines are against severe disease.

11 Jan 2022

Optimal monoclonal antibodies against SARS-CoV-2 variants

Researchers screen different monoclonal antibodies to identify an optimal mAb with higher binding affinity to the receptor-binding domain of SARS-CoV-2.

10 Jan 2022

Medical Science News

New technique could allow more diseases to be safely treated by nanomedicine

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

Engineering higher affinity SARS-CoV-2 antibodies

Adding a tomato concentrate to the diet can reduce intestinal inflammation related to HIV

Withdrawing steroid treatment found to boost SARS-CoV-2 vaccine-induced immunity in kidney transplant recipients

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

Exploring the kinetics of SARS-CoV-2 Marseille-4 variant

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

Evaluating effectiveness of the COVID-19 mRNA-1273 vaccine against Omicron and Delta variants

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

The effect of COVID-19 on routine immunizations for vaccine-preventable diseases

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

Dynamics of infectious diseases and restrictions on the size of social gatherings

Development and validation of 2-gene host-based COVID-19 diagnostic classifiers

Real-world effectiveness of three COVID-19 vaccines

Optimal monoclonal antibodies against SARS-CoV-2 variants

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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