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Rapid antigen tests exhibit high accuracy for COVID-19 screening in children

In a new study, researchers evaluated the sensitivity, specificity, and positive predictive values (PPV) and negative predictive values (NPV) of the Abbott BinaxNOW rapid antigen test against the RT-PCR test in pediatric participants below 18 years in the US with high COVID-19 testing from May 7, 2021, to December 6, 2021.

10 Jan 2022

SARS-CoV-2 Omicron variant's infectivity, vaccine breakthrough, and antibody resistance

A recent study uses an artificial intelligence model to investigate Omicron's mutations and its infectivity, vaccine escape capability, and susceptibility to monoclonal antibodies.

10 Jan 2022

SARS-CoV-2 omicron variant predicted to cause fewer deaths in Florida

Scientists have predicted a lower number of infections and deaths caused by the omicron variant of severe acute respiratory syndrome coronavirus 2 in Florida

10 Jan 2022

SARS-CoV-2 shown to spread through cell-to-cell transmission

A new study investigated SARS-CoV-2 cell-to-cell transmission in the context of cell-free infection and compared it to SARS-CoV.

10 Jan 2022

Declining effectiveness of the BNT162b2 vaccine in adolescents infected with COVID-19

Researchers have conducted a retrospective matched case-control study to determine the protection period conferred by the BNT162b2 vaccine on adolescents aged 12 to 16.

10 Jan 2022

SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

In a new study, researchers used a cell-cell fusion assay to extract potentially cleaved spike protein products from syncytia in order to explore the functional and biochemical characteristics of spike (S) protein when it engages its receptor ACE2 in living cells.

10 Jan 2022

Association of vaccination status with Long COVID symptoms

Scientists examined whether vaccination was associated with reporting long-term symptoms post-SARS-CoV-2 infection.

10 Jan 2022

Researchers plan to review the effect of SARS-CoV-2 on male reproductive health

In a protocol published in BMJ Open, researchers from the Chengdu University of Traditional Chinese Medicine plan to review current studies in this area.

10 Jan 2022

Strategy for capturing SARS-CoV-2 through functionalized cellulose materials

Researchers from Northeastern University have developed a new, more cost-effective method for immobilizing SARS-CoV-2.

10 Jan 2022

SARS-CoV-2 Delta sublineage AY.4.2 shows no increase in cell entry or antibody evasion

Researchers from Germany, in their recent study published in the journal Cellular & Molecular Immunology, have evaluated the mutations in the S protein of one such SARS-CoV-2 strain, a Delta sublineage AY.4.2, which is currently expanding in the UK, and have found that it neither contains any potential for increased cell entry nor antibody escape.

10 Jan 2022

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022

History of SARS-CoV-2 infection affects longitudinal responses to BNT162b2 vaccine

In a recently published article in the journal Cell Reports, scientists have demonstrated that individuals with or without a history of coronavirus disease 2019 (COVID-19) exhibit differential humoral and cellular immune responses 14 days after receiving mRNA-based COVID-19 vaccine developed by Pfizer/BioNTech. However, at a later time point, the responses become comparable between the two groups.

9 Jan 2022

Engineered small extracellular vesicles for the neutralization of SARS-CoV-2

Characterizing these engineered sEVs, the researchers demonstrated that the soluble angiotensin-converting enzyme 2 (sACE-2) loaded sEV successfully binds and thus inhibits the entry of wild-type SARS-CoV-2 as well as its variants, protecting against SARS-CoV-2 infection. They also demonstrated the therapeutic efficacy of these engineered sEVs in vivo.

9 Jan 2022

SARS-CoV-2 Omicron variant uses endosomal entry pathway and grows in upper respiratory tract cells

Researchers demonstrate that the SARS-CoV-2 Omicron variant grows rapidly in human primary nasal epithelial cultures.

9 Jan 2022

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

Researchers investigate the spread and transmission ability of SARS-CoV-2 lineages B.1.619 and B.1.620 in South Korea.

9 Jan 2022

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Researchers developed a human A549 lung epithelial cell-based model to probe SARS-CoV-2 replication.

9 Jan 2022

Study finds novel pathway for understanding why debilitating conditions happen for cancer patients

Severe and persistent disability often undermines the life-saving benefits of cancer treatment. Pain and fatigue - together with sensory, motor, and cognitive disorders - are chief among the constellation of side effects that occur with the platinum-based agents used widely in chemotherapy treatments worldwide.

9 Jan 2022

Medical Science News

Rapid antigen tests exhibit high accuracy for COVID-19 screening in children

SARS-CoV-2 Omicron variant's infectivity, vaccine breakthrough, and antibody resistance

SARS-CoV-2 omicron variant predicted to cause fewer deaths in Florida

SARS-CoV-2 shown to spread through cell-to-cell transmission

Declining effectiveness of the BNT162b2 vaccine in adolescents infected with COVID-19

SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

Association of vaccination status with Long COVID symptoms

Researchers plan to review the effect of SARS-CoV-2 on male reproductive health

Strategy for capturing SARS-CoV-2 through functionalized cellulose materials

SARS-CoV-2 Delta sublineage AY.4.2 shows no increase in cell entry or antibody evasion

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

History of SARS-CoV-2 infection affects longitudinal responses to BNT162b2 vaccine

Engineered small extracellular vesicles for the neutralization of SARS-CoV-2

SARS-CoV-2 Omicron variant uses endosomal entry pathway and grows in upper respiratory tract cells

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Study finds novel pathway for understanding why debilitating conditions happen for cancer patients

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Dual-receptors help widespread dissemination of SARS-CoV-2

Study reveals how the brain’s blue spot shapes selective attention

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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