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High genetic running capacity promotes healthier metabolism in tissues as we age

High running capacity is associated with health and longevity. However, whether high genetic running capacity promotes more efficient metabolism with aging is not known.

14 Jun 2021

Stents inspired by kirigami could deliver drugs to tubular organs

Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.

14 Jun 2021

New study pushes the memory clock back over a year

On average the earliest memories that people can recall point back to when they were just two-and-a-half years old, a new study suggests.

14 Jun 2021

Researchers demonstrate an alternative way to produce highly detailed images of the brain

The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.

14 Jun 2021

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Researchers have developed a new approach to gene therapy that leans on the common pain reliever acetaminophen to force a variety of genetic diseases into remission.

14 Jun 2021

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

Biomarkers are important determinants of appropriate and effective therapeutic approaches for various diseases including cancer.

14 Jun 2021

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

14 Jun 2021

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

The disease is so rare and complex that its acronym is hard to pronounce. But for infants unlucky enough to be born with this lung disease, the outcome is usually fatal.

14 Jun 2021

Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

Diseases that affect tubular structures in the body, such as the gastrointestinal (GI) system, vasculature and airway, present a unique challenge for delivering local treatments.

14 Jun 2021

Plant-based diet appears to offer protection against hypertension and preeclampsia

A plant-based diet appears to afford significant protection to rats bred to become hypertensive on a high-salt diet, scientists report. When the rats become pregnant, the whole grain diet also protects the mothers and their offspring from deadly preeclampsia.

14 Jun 2021

Researchers examine the importance of time after COVID-19 vaccination

A new study has been published on the medRxiv* preprint server, which deals with the importance of time post-vaccination based on the quantification of VOC immune evasion. The current study developed a toy model to estimate the effectiveness of the vaccines against VOC over time. Researchers have shown that the estimated value is highly dependent on time post-vaccination. Additionally, this model can describe the implications of changes in vaccine efficacy against VOC.

14 Jun 2021

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

LSU Health New Orleans has been awarded $2.38 million in funding to lead partnerships to sequence SARS-CoV-2 variants.

14 Jun 2021

Robust immunity against SARS-CoV-2 with Pfizer vaccine is mediated by memory B cells

A reassuring study, released as a preprint on the medRxiv* server, from a multi-institutional team of researchers in Italy suggests that with the Pfizer-BioNTech BNT162b2 vaccine, post-vaccination immunity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is both robust and durable.

14 Jun 2021

Intranasal monoclonal SARS-CoV-2 antibody therapy shows promise in preclinical trials

A new study, released as a preprint on the bioRxiv* server, presents a new monoclonal antibody (MAb) called DZIF-10c that powerfully neutralizes SARS-CoV-2, including the current variants of concern (VOCs). With high bioavailability in the lungs and wide distribution in the body, the antibody was able to prevent SARS-CoV-2 infection in mice after intranasal administration.

14 Jun 2021

Bone density scan can detect calcium build-up linked to higher risk of serious falls

The build-up of calcium in a major blood vessel is linked with a 39 per cent higher risk of serious falls in older women, new Edith Cowan University (ECU) research has found.

14 Jun 2021

Fatty acid binding site on SARS-CoV-2 spike triggers spike monomer crosstalk that is key to infectivity

A new study, released as a preprint on the bioRxiv* server, examines the role played by a fatty acid called linoleic acid (LA) that attaches at a binding site near the receptor-binding domain (RBD) of the spike protein. The spike exists as a homotrimer in open or closed conformations. In the former, at least one RBD points upwards.

14 Jun 2021

Can rapid antigen tests help screen for COVID-19?

The spread of SARS-CoV-2 is driven by the high proportion of asymptomatic and very mild infections, allowing people to move around and engage in public activity normally. There are many modeling studies that suggest that large-scale screening for the presence of this virus can help curb transmission at this point, from people with few or no symptoms. A new study points out the accuracy of SARS-CoV-2 antigen-detection rapid diagnostic tests for this purpose when used at the point-of-care.

14 Jun 2021

COVID-19 in pregnancy could be less severe than previously thought: A Danish case study

A reassuring study by researchers in Denmark indicates that while 5% of pregnant women with COVID-19 may require hospitalization, severe maternal and neonatal outcomes are rare.

14 Jun 2021

Delays and shortages hit SARS-CoV-2 genomic surveillance program

A new study from the Institute of Bioinformatics and Applied Biotechnology (IBAB), Bengaluru, India, provides an overview of how well this important monitoring mechanism is functioning around the world. The team has released their findings as a preprint on the bioRxiv* server.

14 Jun 2021

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

A recent study by researchers in Canada shows how mutations in newly emerging lineages of SARS-CoV-2 may disrupt the sequencing process and thus interfere with this important area of research.

14 Jun 2021

Medical Science News

High genetic running capacity promotes healthier metabolism in tissues as we age

Stents inspired by kirigami could deliver drugs to tubular organs

New study pushes the memory clock back over a year

Researchers demonstrate an alternative way to produce highly detailed images of the brain

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

Plant-based diet appears to offer protection against hypertension and preeclampsia

Researchers examine the importance of time after COVID-19 vaccination

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

Robust immunity against SARS-CoV-2 with Pfizer vaccine is mediated by memory B cells

Intranasal monoclonal SARS-CoV-2 antibody therapy shows promise in preclinical trials

Bone density scan can detect calcium build-up linked to higher risk of serious falls

Fatty acid binding site on SARS-CoV-2 spike triggers spike monomer crosstalk that is key to infectivity

Can rapid antigen tests help screen for COVID-19?

COVID-19 in pregnancy could be less severe than previously thought: A Danish case study

Delays and shortages hit SARS-CoV-2 genomic surveillance program

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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