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Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

A new study aimed to clarify whether extensive RBD mutations could affect the magnitude and immunodominance hierarchy of the host antibody response.

18 Feb 2022

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Melanoma, a type of skin cancer, is often curable when detected and treated in its early stages. However, the disease can rapidly spread to other organs in the body and become deadly. According to the American Cancer Society, more than 7,600 people die of the disease each year in the United States.

17 Feb 2022

Intermediate size nanoparticles may be effective at stopping internal bleeding

Traumatic injuries are the leading cause of death in the U.S. among people 45 and under, and such injuries account for more than 3 million deaths per year worldwide.

17 Feb 2022

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

Researchers assess how fast the SARS-CoV-2 Alpha and Delta variants transmit from transmission data in a household study.

17 Feb 2022

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease.

17 Feb 2022

Messenger RNA can be used at low doses to regenerate bone without side effects

Although fractures normally heal, bone will not regenerate under several circumstances. When bone does not regenerate, major clinical problems could result, including amputation.

17 Feb 2022

New high-risk subtype of relapsed pediatric AML revealed

When acute myeloid leukemia (AML) relapses, it is more difficult to treat and outcomes are dismal. Scientists at St. Jude Children's Research Hospital have discovered a mutation in pediatric AML that physicians can use to identify high-risk patients and better guide treatment.

17 Feb 2022

Older adults can prevent memory decline by sticking to regular exercise

We all know exercise is good for us, but that still leaves plenty of questions. How much exercise? Who benefits the most? And when in our lives? New research led by University of Pittsburgh psychologists pools data from dozens of studies to answer these questions, showing that older adults may be able to prevent declines in a certain kind of memory by sticking to regular exercise.

17 Feb 2022

Study reveals mechanisms associated with severe blood clotting in COVID-19 patients

After studying blood samples from 244 patients hospitalized for COVID-19, a group of researchers, including those who work at the National Institutes of Health, identified “rogue antibodies” that correlate with severe illness and may help explain mechanisms associated with severe blood clotting.

17 Feb 2022

COVID-19 vaccine-induced immunity in heart and kidney solid organ transplant recipients

The present study entailed assessments of both infected and uninfected SOTRs against the D614G-CoV2 baseline virus and eight other variants.

17 Feb 2022

Vaccination likely to be more protective against SARS-CoV-2 viral variants than natural infection

Antibodies generated by COVID-19 vaccines are more suited to recognizing viral variants than antibodies that arise from natural infection, according to a study by researchers at Stanford Medicine.

17 Feb 2022

Study characterizes brain changes in adolescents affected by juvenile fibromyalgia

Juvenile fibromyalgia is a syndrome characterized by a chronic pain affecting the whole body. It also causes fatigue as well as sleep and mood disorders.

17 Feb 2022

Skin cells outside of the hair follicles play large role in the development of a pimple

Acne is among the most common skin diseases in the United States, according to the American Academy of Dermatology Association, affecting up to 50 million Americans each year. It is also among the least studied.

17 Feb 2022

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Joint study will assess clinical value of comprehensive genomic profiling (CGP) on cancer therapy options in patients with advanced disease

From Illumina, Inc. 17 Feb 2022

Search for a treatment to stop nerve cell degeneration yields promising results

Researchers at the University of Illinois Chicago found promising results in their search for a treatment to stop nerve cell degeneration that happens in some types of disorders, such as hereditary spastic paraplegia and Parkinson's disease, which can cause significant disability.

17 Feb 2022

Medical Science News

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Intermediate size nanoparticles may be effective at stopping internal bleeding

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

Messenger RNA can be used at low doses to regenerate bone without side effects

New high-risk subtype of relapsed pediatric AML revealed

Older adults can prevent memory decline by sticking to regular exercise

Study reveals mechanisms associated with severe blood clotting in COVID-19 patients

COVID-19 vaccine-induced immunity in heart and kidney solid organ transplant recipients

Vaccination likely to be more protective against SARS-CoV-2 viral variants than natural infection

Study characterizes brain changes in adolescents affected by juvenile fibromyalgia

Skin cells outside of the hair follicles play large role in the development of a pimple

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Search for a treatment to stop nerve cell degeneration yields promising results

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Study determines 115 long COVID symptoms and their associated risk factors

Case ascertainment of myocarditis following COVID-19 booster vaccine

Memory B cell repertoire in a longitudinal cohort of individuals receiving 3 COVID-19 mRNA vaccine doses

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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