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New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Researchers identify a common mechanism underlying diverse brain disorders

Researchers at Vanderbilt University Medical Center have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.

9 Jun 2021

Researchers find brain alterations in obese children

Obesity is generally linked to poor eating habits and the availability of tasty, high-calorie foods. However, a new study led by researchers from the Magnetic Resonance Imaging Research Unit in the Department of Radiology at Hospital del Mar and the Barcelona Institute for Global Health, a center supported by the "la Caixa" Foundation, has found that more elements are involved.

9 Jun 2021

Protein in prostate cancer may prevent tumor from spreading to the bone

Prostate cancer is the second most common cancer among men, according to the American Cancer Society. It's also one of the trickiest cancers to diagnose and treat.

9 Jun 2021

Cold winter temperatures may accelerate spread of SARS-CoV-2

Writing in the journal Frontiers in Public Health, the team from Weifang Medical University said: “We believe that the low-temperature environment in winter may accelerate the spread of the outbreak and that new outbreaks may occur.”

9 Jun 2021

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

A new bioRxiv preprint attempts to make some sense of why certain people experience more severe forms of COVID-19 as compared to others by pointing to the increase in virus binding that occurs in the presence of smoking or vaping.

9 Jun 2021

Researchers in Canada conduct a comparative study of household secondary attack rates connected with SARS-CoV-2 variants of concern

Scientists are considering a third surge in COVID-19 incidence owing to the emergence of highly transmissible SARS-CoV-2 variants of concern (VOC). SARS-CoV-2 is the causal agent of the current COVID-19 pandemic. Some of these VOCs have been reported to have a rate of transmission much higher than the infectivity of the ancestral strain that had emerged in Wuhan, China, in 2019.

9 Jun 2021

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

In a recent study published in the journal Pathogens, researchers carried out a molecular docking study for 17 structural analogs prepared from natural maslinic and oleanolic acids and screened them against SARS-CoV-2 main protease. They also experimentally validated the data by determining the half-maximal cytotoxic and inhibitory concentrations of each of the 17 compounds. The researchers investigated whether the compound with antiviral activity affected viral adsorption, replication, or viricidal effect using a plaque infectivity reduction assay.

9 Jun 2021

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Researchers from the US used a systems immunology approach where they combined high-dimensional flow cytometry and multi-omics single-cell sequencing analyses of immune profiles taken from the airways and matching blood samples of Black/AA patients.

9 Jun 2021

What are the challenges of SARS-CoV-2 serosurveillance in COVID-19 vaccine recipients?

An opinion paper by researchers from the US and Italy recently discussed various aspects of monitoring anti-SARS-CoV-2 antibodies before and after receiving COVID-19 vaccination to highlight the pros and cons of this monitoring strategy. This paper is published in the open-access journal Diagnostics.

9 Jun 2021

Social media ‘bots’ continue to spread misinformation on mask wearing amid COVID-19 pandemic

While not a new problem, the spread of misinformation throughout the coronavirus disease 2019 (COVID-19) pandemic has exploded on almost every social media platform. Recently, a group of researchers analyzed conversations on public Facebook groups to explored automated misinformation on mask-wearing. The team published their findings as a research letter in the JAMA Internal Medicine journal.

9 Jun 2021

A closer look at how COVID-19 damages human lungs

A recent study conducted at the United States Department of Energy’s (DOE) Brookhaven National Laboratory provides the first atomic-level detailed model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope protein when bound to human proteins within the lungs. The study was recently published in Nature Communications.

9 Jun 2021

European grant awarded for innovative orthopedic training simulator

June 9, 2021, Zurich, Switzerland: VirtaMed, the world leader in data-driven medical simulation training, together with the Centre Hospitalier de Luxembourg (CHL), a public hospital of Luxembourg city, will develop a mixed reality simulator to support surgical skills training for advanced arthroscopic meniscus repair.

From VirtaMed 9 Jun 2021

NIH-funded study to explore liquid surface coatings for reducing catheter-associated infections

A novel liquid surface coating on human catheters could help reduce protein deposition that leads to urinary tract and bloodstream infections, according to researchers at the University of Maine and University of Notre Dame who are leading a study funded by the National Institutes of Health.

9 Jun 2021

Microgel-coated mesenchymal stromal cells can reverse pulmonary fibrosis

Researchers at the University of Illinois Chicago have shown that even after lung tissue has been damaged, it may be possible to reverse fibrosis and promote tissue repair through treatment with microgel-coated mesenchymal stromal cells.

9 Jun 2021

Senolytics reduce inflammation, illness, and mortality from COVID in older mice

Mayo Clinic researchers and colleagues at the University of Minnesota showed that COVID-19 exacerbates the damaging impact of senescent cells in the body.

9 Jun 2021

Researchers map brain activity that flows when people learn a new skill

In a study of healthy volunteers, National Institutes of Health researchers have mapped out the brain activity that flows when we learn a new skill, such as playing a new song on the piano, and discovered why taking short breaks from practice is a key to learning.

9 Jun 2021

Researchers identify novel gene that controls sleep/wake cycle in mice

That internal nagging feeling that drives you to seek sleep at night and wake in the morning to eat, work, and play, is, it turns out, genetic, and it's not just in people.

9 Jun 2021

Cyperus rotundus medicinal plant shows promise for novel COVID-19 therapeutics

Cyperus rotundus is a plant with a history as herbal medicine, containing many chemical substances frequently found to be drug-like in character: flavonoids, terpenoids, and the like. Compounds sourced from the plant have demonstrated some inhibitory activity against HIV by modulation of the CYP3A4 enzyme, and thus in a drug lead discovery effort, Kumar et al. (July 2021) computationally screened these natural compounds against MPRO in a paper recently published to Computers in Biology and Medicine.

9 Jun 2021

Medical Science News

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Researchers identify a common mechanism underlying diverse brain disorders

Researchers find brain alterations in obese children

Protein in prostate cancer may prevent tumor from spreading to the bone

Cold winter temperatures may accelerate spread of SARS-CoV-2

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

Researchers in Canada conduct a comparative study of household secondary attack rates connected with SARS-CoV-2 variants of concern

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

What are the challenges of SARS-CoV-2 serosurveillance in COVID-19 vaccine recipients?

Social media ‘bots’ continue to spread misinformation on mask wearing amid COVID-19 pandemic

A closer look at how COVID-19 damages human lungs

European grant awarded for innovative orthopedic training simulator

NIH-funded study to explore liquid surface coatings for reducing catheter-associated infections

Microgel-coated mesenchymal stromal cells can reverse pulmonary fibrosis

Senolytics reduce inflammation, illness, and mortality from COVID in older mice

Researchers map brain activity that flows when people learn a new skill

Researchers identify novel gene that controls sleep/wake cycle in mice

Cyperus rotundus medicinal plant shows promise for novel COVID-19 therapeutics

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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