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Scientists develop mouse-specific SARS-CoV-2 strains that efficiently replicate in standard laboratory mice

A team of scientists in France recently developed a mouse-adapted strain of SARS-CoV-2 that efficiently replicates in the lungs of standard laboratory mice and induces mild to moderate disease. The study is currently available on the bioRxiv* preprint server.

13 Jul 2021

Study examines asymptomatic, presymptomatic and symptomatic transmission dynamics of SARS-CoV-2

A new preprint, available on the medRxiv* server, describes how researchers found at least a third of infected individuals to be asymptomatic, but that a fifth of them successfully passed on the virus to others. In comparison, about a quarter of symptomatic cases did so, especially when the symptoms included fever, cough and shortness of breath. In these circumstances, up to 30% of them transmitted the virus.

13 Jul 2021

Colonization by SARS-CoV-2 not synonymous with infection, screening study highlights

A new study released as a preprint on the medRxiv* server throws cold water on this notion, however, by demonstrating that in a set of asymptomatic cases, less than a tenth actually had evidence of SARS-CoV-2 infection. This finding has serious implications for the practices mentioned above, since they may be neither justifiable nor cost-effective as means to break the chain of viral transmission.

13 Jul 2021

Prioritization of COVID-19 vaccination is improved by including health and socioeconomic factors

Allocating COVID-19 vaccines has been determined primarily by age group, but a new study shows that other factors including health risks are also important.

13 Jul 2021

Study reports low risk for COVID-19 in Emergency Medical Service personnel exposed to aerosol-generating procedures

The U.S. Centers for Disease Control and Prevention (CDC) reports that emergency medical service personnel exposed to aerosol-generating procedures (AGP) on COVID-19 patients are generally at low risk of infection. The findings, published in CDC’s Emerging Infectious Diseases, support clinical strategies that maintain established and evidence-based practices for emergency conditions.

13 Jul 2021

Patient characteristics including demographic factors and comorbidities can accurately predict the outcome of COVID-19 infection severity

New machine learning models incorporating COVID-19 infection data show that patient demography is a key predictor of infection outcome.

13 Jul 2021

3D printing a way out of COVID-19

In a recent review published in the journal, Advanced Functional Materials, researchers K. P. A. Kumar and Martin Pumera focused on the contributions of 3D printing technology towards the health sector in the wake of this deadly pandemic.

13 Jul 2021

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

Now, a new systematic review has been published in the journal Animals that focuses on the clinical symptoms in felines diagnosed with SARS-CoV-2 worldwide.

13 Jul 2021

UT Austin statisticians develop new way to model how the brain learns language

A cross-disciplinary team including University of Texas at Austin statisticians Giorgio Paulon and Abhra Sarkar have received the Mitchell Prize, a top prize in the field, for their study modeling what happens in the brains of nonnative English speakers learning another language's tonal differences.

13 Jul 2021

Static magnetic field from MRI scanner decreases blood-brain barrier opening volume

MRI-guided focused ultrasound combined with microbubbles can open the blood-brain barrier (BBB) and allow therapeutic drugs to reach the diseased brain location under the guidance of MRI.

13 Jul 2021

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

A team of scientists from France has recently demonstrated photosensitive antiviral activity of the natural compound pheophorbide a (Pba) against a broad range of enveloped viruses, including coronaviruses.

12 Jul 2021

Selective immunotoxins may help treat liver fibrosis

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

12 Jul 2021

Specialized protein appears to regulate key step in cancer metastasis

Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.

12 Jul 2021

Optimizing the operation of MRI scanners to visualize finer details of the brain

Experts in magnetic resonance imaging (MRI) at the DZNE are optimizing the operation of MRI scanners as part of an international research effort to enable visualization of finer details of the human brain.

12 Jul 2021

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.

12 Jul 2021

UCR scientists receive additional federal funding to boost research on brain injury

Earlier this year, Viji Santhakumar, an associate professor of molecular, cell and systems biology at the University of California, Riverside, received funding from the National Institute of Neurological Disaster and Stroke of the National Institutes of Health, or NIH, to further pursue research on moderate concussive brain injury.

12 Jul 2021

Students at Lewis Katz School of Medicine stand to benefit from new $1 million NIGMS grant

Rapid evolution in the field of biomedical research demands well-trained scientists. Adapting biomedical research training programs to keep up with the increasingly complex and interdisciplinary nature of the field, however, presents complex challenges for higher-education institutions.

12 Jul 2021

Nose drops of modified 'friendly' bacteria offer protection against meningitis

A world-first trial has shown that nose drops of modified 'friendly' bacteria protect against meningitis.

12 Jul 2021

Groundbreaking technology offers hope for people who have lost their sense of touch

Tel Aviv University's new and groundbreaking technology inspires hope among people who have lost their sense of touch in the nerves of a limb following amputation or injury.

12 Jul 2021

Study could guide future treatment of multisystem inflammatory syndrome in children

Children and adolescents with multisystem inflammatory syndrome in children (MIS-C) who are treated initially with intravenous immune globulin (IVIG) and glucocorticoids have reduced risk for serious short-term outcomes, including cardiovascular dysfunction, than those who receive an initial treatment of IVIG alone, a new study finds.

12 Jul 2021

Medical Science News

Scientists develop mouse-specific SARS-CoV-2 strains that efficiently replicate in standard laboratory mice

Study examines asymptomatic, presymptomatic and symptomatic transmission dynamics of SARS-CoV-2

Colonization by SARS-CoV-2 not synonymous with infection, screening study highlights

Prioritization of COVID-19 vaccination is improved by including health and socioeconomic factors

Study reports low risk for COVID-19 in Emergency Medical Service personnel exposed to aerosol-generating procedures

Patient characteristics including demographic factors and comorbidities can accurately predict the outcome of COVID-19 infection severity

3D printing a way out of COVID-19

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

UT Austin statisticians develop new way to model how the brain learns language

Static magnetic field from MRI scanner decreases blood-brain barrier opening volume

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

Selective immunotoxins may help treat liver fibrosis

Specialized protein appears to regulate key step in cancer metastasis

Optimizing the operation of MRI scanners to visualize finer details of the brain

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

UCR scientists receive additional federal funding to boost research on brain injury

Students at Lewis Katz School of Medicine stand to benefit from new $1 million NIGMS grant

Nose drops of modified 'friendly' bacteria offer protection against meningitis

Groundbreaking technology offers hope for people who have lost their sense of touch

Study could guide future treatment of multisystem inflammatory syndrome in children

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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