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New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

New research from Johns Hopkins Kimmel Cancer Center investigators shows why some drugs in clinical trials for treating a form of acute myeloid leukemia (AML) often fail and demonstrates a way to restore their effectiveness.

27 Sep 2021

Chronic COVID-19 and divergent variants of SARS-CoV-2

A new study discusses the isolation of two variants of concern (VOCs) from an immunocompromised COVID-19 patient.

27 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

Addictive psychostimulants, from nicotine in cigarettes to illicit drugs like methamphetamine and cocaine, affect different regions of the brain. The same is believed true during withdrawal; finding a common brain pathway has proved elusive.

27 Sep 2021

$6 million CDC grant to support U-M researchers in reducing youth firearm violence

Middle- and high school-age children across the United States are more likely to die as the result of a firearm injury than from any other single cause of death.

27 Sep 2021

Limited evidence colchicine reduces COVID-19 related hospitalization

The present randomized clinical trial attempted to study if colchicine will effectively hasten recovery and reduce COVID-19 associated hospitalizations or death.

27 Sep 2021

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

The findings from this study suggest that HPNs may inhibit viral replication and budding.

27 Sep 2021

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

A team from the National Institute for Infectious Diseases “L. Spallanzani” (INMI) has recently reported their study on 94 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections (47.9% symptomatic, 52.1% asymptomatic) that occurred after the first or second vaccine dose against SARS-CoV-2 in the Lazio region (Central Italy).

27 Sep 2021

New blood test to diagnose Alzheimer's disease using atomic force microscopy

If the suspicion of Alzheimer's disease creeps up, those affected must prepare themselves for lengthy and complex procedures until the case is clear.

27 Sep 2021

SARS-CoV-2 entry inhibitors show antiviral activity

A new study used a combination of a computer-aided drug design approach and cell-based in vitro assays to identify five potential SARS-CoV-2 inhibitors.

27 Sep 2021

New breakthrough in the development of more natural and continuous BCI control systems

For the first time ever, the intention of a continuous movement was able to be read out from non-invasive brain signals at TU Graz. This success enables more natural and non-invasive control of neuroprostheses to be carried out in real-time.

27 Sep 2021

Irish meat processing plant COVID-19 outbreak: a retrospective study

A new study involved a retrospective investigation of the outbreak of COVID-19 in an Irish meat plant.

27 Sep 2021

Healthy gut microbiome needed for skeletal muscles to fully grow after exercising, study suggests

If further research can identify the substances that the bacteria of the gut are making to help muscles grow following exercise, we might be able to use some of those substances to promote the growth of muscles in people suffering from the loss of muscle as typically seen with aging or cancer.

27 Sep 2021

Study reveals surfaces of SARS-CoV-2 spike most resistant to antibody escape

A team of international scientists has formed a consortium to map the epitope landscape of a range of therapeutic monoclonal antibodies on the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Moreover, the scientists characterized the neutralization potency of these antibodies and have investigated how emerging viral variants with spike mutations can impact antibody-mediated neutralization. They have recently published the consortium findings in the journal Science.

27 Sep 2021

Industrial chemical perfluorobutanoic acid less likely to accumulate in human lungs and kidneys

A 2013 study by Pérez et al. reported a very high accumulation of the industrial chemical perfluorobutanoic acid (PFBA) in human lungs and kidneys. The German Federal Institute for Risk Assessment (BfR) checked these results using a more precise quantification method. The result: Only one sample contained a quantifiable PFBA value of 0.17 nanograms (ng) per gram (g) of lung tissue.

25 Sep 2021

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

As mRNA-based SARS-CoV-2 vaccines are deployed to protect hundreds of millions of people across the world and point the way to end the deadly global COVID-19 pandemic, the University of Pennsylvania scientists whose prescient discovery science effort laid the foundation for swift vaccine development have been awarded the 2021 Lasker~DeBakey Clinical Medical Research Award.

24 Sep 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Harmful side effects from a common chemotherapy drug could be the result of a single mutation, according to a study published in Cell Stem Cell.

24 Sep 2021

Further evidence of safety and efficacy of mRNA-1273 vaccine in preventing symptomatic COVID-19 and SARS-CoV-2 infection

A recent study supports the efficacy of the mRNA-1273 vaccine in preventing COVID-19 illness and disease severity.

24 Sep 2021

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

A new study presents initial results from a randomized, placebo-controlled phase 1/2 trial in Thailand.

24 Sep 2021

Radiation therapy for ventricular tachycardia may revert heart muscle cells to a younger state

Radiation therapy for ventricular tachycardia — a life-threatening irregular heart rhythm — appears to work by reverting heart muscle cells to a younger state, reducing the irregular rhythms, according to a new study from Washington University School of Medicine in St. Louis.

24 Sep 2021

Medical Science News

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

Chronic COVID-19 and divergent variants of SARS-CoV-2

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

$6 million CDC grant to support U-M researchers in reducing youth firearm violence

Limited evidence colchicine reduces COVID-19 related hospitalization

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

New blood test to diagnose Alzheimer's disease using atomic force microscopy

SARS-CoV-2 entry inhibitors show antiviral activity

New breakthrough in the development of more natural and continuous BCI control systems

Irish meat processing plant COVID-19 outbreak: a retrospective study

Healthy gut microbiome needed for skeletal muscles to fully grow after exercising, study suggests

Study reveals surfaces of SARS-CoV-2 spike most resistant to antibody escape

Industrial chemical perfluorobutanoic acid less likely to accumulate in human lungs and kidneys

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

Cardiotoxic effects of common chemotherapy drug could be prevented

Further evidence of safety and efficacy of mRNA-1273 vaccine in preventing symptomatic COVID-19 and SARS-CoV-2 infection

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

Radiation therapy for ventricular tachycardia may revert heart muscle cells to a younger state

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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