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MVA SARS-CoV-2 vaccine candidate shows strong immunogenicity in preclinical trials

A new study reports the preclinical testing of a recombinant MVA (rMVA) candidate vaccine against SARS-CoV-2, the agent that is causing the current COVID-19 pandemic.

14 Jan 2021

Could intranasal SARS-CoV-2 vaccines be a practical alternative to intramuscular shots?

The unchecked advance of COVID-19 has made it a top public health priority to produce a vaccine capable of inducing a safe and powerful protective response against its causative pathogen: SARS-CoV-2. An encouraging new study shows the immunogenicity, safety, and protective efficacy, of a Newcastle disease virus (NDV)-based intranasal vector vaccine in animal studies.

14 Jan 2021

Researchers develop a tiny, yet effective method for preventing premature birth

In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a tiny, yet effective method for preventing premature birth.

13 Jan 2021

Study reveals cardiac protein as a new target for different types of heart disease

Like a failing fuel pump that causes a loss of engine power in a car, a diseased heart can take a serious toll on the body's performance. For some patients, tasks like walking up a flight of stairs or walking across a room eventually turn into exhausting endeavors.

13 Jan 2021

Scientists identify key enzyme as driver of autoimmune blistering diseases

The Granzyme B (GzmB) enzyme, which accumulates in certain tissues as we age, has been identified as a driver of itchy and sometimes life-threatening autoimmune conditions known as pemphigoid diseases (PDs), which cause blistering and skin erosion below the skin's surface.

13 Jan 2021

How has the UK-derived SARS-CoV-2 mutant strain spread internationally?

Researchers analyzed Facebook-based mobility data and found that travelers from UK may have spread the new SARS-CoV-2 strain that originated in the UK to at least 16 countries by the beginning of December 2020.

13 Jan 2021

COVID-19 survivors can show persistent symptoms six months after recovery, study finds

A team of researchers conduct a large study exploring the persistence of COVID-19 symptoms in recovered patients.

13 Jan 2021

Moderna to develop three new mRNA-based vaccines against HIV, influenza, and the Nipah virus

Morderna has announced plans to develop a range of new mRNA-based vaccines against other viruses, including the influenza virus, human immunodeficiency virus (HIV), and the Nipah virus.

13 Jan 2021

Researchers map genetic changes that may have facilitated SARS-CoV-2’s jump from bats to humans

Researchers from the University of Cambridge and the Pirbright Institute in the UK have identified key genetic changes in SARS-CoV-2 that may be responsible for the virus’s jump from bats to humans. The team also determined which animals contain cellular receptors that allow the virus to enter cells more effectively, zoning in on potential animals that acted as an intermediary host in facilitating SARS-CoV-2’s zoonosis.

13 Jan 2021

New N501 SARS-CoV-2 mutation may have been circulating in Italy since August 2020

A recent study shows that mutated SARS-CoV-2 strains with a substitution at position 501 might have circulated unnoticed even before the end of September 2020, when the rapid emergence of B.1.1.7 lineage (carrying the N501Y mutation) was initially reported.

13 Jan 2021

New findings could help better understand the mechanisms underlying severe malaria

The levels of small molecules called microRNAs (miRNAs) circulating in blood could help identify early on children with life-threatening forms of malaria, according to a study led by the Barcelona Institute for Global Health, an institution supported by "la Caixa" Foundation, in collaboration with the Manhiça Health Research Center (CISM) in Mozambique.

13 Jan 2021

Study shows faster uptake of chemicals in people with a genetically weakened skin barrier

The ability of our skin to protect us from chemicals is something we inherit. Some people are less well-protected which could imply an increased risk of being afflicted by skin disease or cancer.

13 Jan 2021

New UK-derived SARS-CoV-2 variant does not affect neutralizing antibodies efficiency, study says

A team of scientists conducted structural analysis of a newly emerged UK variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They present evidence that suggests that while the new variant has increased infectivity it is not resistant to neutralizing antibodies.

13 Jan 2021

Researchers use urine test to identify and verify a patient's type of asthma

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma.

13 Jan 2021

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Glioblastoma brain tumors are especially perplexing. Inevitably lethal, the tumors occasionally respond to new immunotherapies after they've grown back, enabling up to 20% of patients to live well beyond predicted survival times.

13 Jan 2021

Could fenofibrate be an effective antiviral against SARS-CoV-2?

The resurgence of COVID-19 pandemic, caused by the SARS-CoV-2, has led to renewed efforts to find effective antivirals, both newly developed or repurposed drugs. A study reports the efficacy of the cholesterol-reducing drug fenofibrate in reducing infection rates of SARS-CoV-2 in cultured cells.

13 Jan 2021

Change in evidence-based guidelines for vasectomy may reduce number of follow-up tests

A change in evidence-based guidelines for vasectomy may have led to a reduction in the number of follow-up tests to confirm the procedure was successful, reports a study in Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

13 Jan 2021

New technology could protect against different coronavirus variants

The SARS-CoV-2 virus that is causing the COVID-19 pandemic is just one of many different viruses in the coronavirus family.

13 Jan 2021

Scientists identify bacteria-based approach against cancer

The body's immune system is the first line of defense against infections like bacteria, viruses or cancers. Some cancers, however, have developed the art of molecular deception to avoid destruction by the body's immune system.

13 Jan 2021

Researchers develop novel antibody fragments against SARS coronavirus-2

An international research team led by the University of Bonn (Germany) has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

Medical Science News

MVA SARS-CoV-2 vaccine candidate shows strong immunogenicity in preclinical trials

Could intranasal SARS-CoV-2 vaccines be a practical alternative to intramuscular shots?

Researchers develop a tiny, yet effective method for preventing premature birth

Study reveals cardiac protein as a new target for different types of heart disease

Scientists identify key enzyme as driver of autoimmune blistering diseases

How has the UK-derived SARS-CoV-2 mutant strain spread internationally?

COVID-19 survivors can show persistent symptoms six months after recovery, study finds

Moderna to develop three new mRNA-based vaccines against HIV, influenza, and the Nipah virus

Researchers map genetic changes that may have facilitated SARS-CoV-2’s jump from bats to humans

New N501 SARS-CoV-2 mutation may have been circulating in Italy since August 2020

New findings could help better understand the mechanisms underlying severe malaria

Study shows faster uptake of chemicals in people with a genetically weakened skin barrier

New UK-derived SARS-CoV-2 variant does not affect neutralizing antibodies efficiency, study says

Researchers use urine test to identify and verify a patient's type of asthma

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Could fenofibrate be an effective antiviral against SARS-CoV-2?

Change in evidence-based guidelines for vasectomy may reduce number of follow-up tests

New technology could protect against different coronavirus variants

Scientists identify bacteria-based approach against cancer

Researchers develop novel antibody fragments against SARS coronavirus-2

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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