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Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.

19 Feb 2021

Molecular modeling helps identify the binding site of antidepressantss

The effects of selective serotonin reuptake inhibitors (SSRIs) and other conventional antidepressants are believed to be based on their increasing the levels of serotonin and noradrenalin in synapses, while ketamine, a new rapid-acting antidepressant, is thought to function by inhibiting receptors for the neurotransmitter glutamate.

19 Feb 2021

Person in the midst of vivid dream can engage in real-time communication

Dreams take us to what feels like a different reality. They also happen while we're fast asleep. So, you might not expect that a person in the midst of a vivid dream would be able to perceive questions and provide answers to them.

19 Feb 2021

Inhibitors to target SARS-CoV-2 viral protein display strong antiviral activity in transgenic mouse model

Inhibitors based on approved drugs and designed to disrupt the SARS-CoV-2 viral protein Mpro display strong antiviral activity both in vitro and in a transgenic mouse model, a new study reports.

18 Feb 2021

Specific cell-to-cell communication associated with progression of gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are a subytpe of cancers known as sarcomas. GIST is the most common type of sarcoma with approximately 5,000 to 6,000 new patient cases annually in the United States.

18 Feb 2021

Immune response to SARS-CoV-2 may be limited by a set of genes

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines.

18 Feb 2021

Human brain adapts to loss of sensory information by tapping into visual cues

Evidence that a sense of our physical selves can develop even without the sense of touch has been uncovered in a new study by researchers in the UK and the United States.

18 Feb 2021

Study shows positive correlation between cardiorespiratory fitness and cognitive health in preschoolers

Researchers report that 4-6-year-old children who walk further than their peers during a timed test - a method used to estimate cardiorespiratory health - also do better on cognitive tests and other measures of brain function.

18 Feb 2021

Polycomb complexes found to be essential for proper skin development

Mount Sinai researchers have discovered that Polycomb complexes, groups of proteins that maintain gene expression patterns, are essential for proper skin development, according to a paper published in Genes & Development on February 18.

18 Feb 2021

Could measles virus vectors be used for a new COVID-19 vaccine?

A research team at the Institut Pasteur in France describes the successful development of such a vaccine utilizing a measles virus vector.

18 Feb 2021

Researchers discover potential new way to target pancreatic tumors with high IFN signaling

UCLA Jonsson Comprehensive Cancer Center researchers have uncovered a potential new way to target pancreatic tumors that express high intratumoral interferon signaling (IFN).

18 Feb 2021

Early immunosuppressive biomarkers could predict bone regeneration after trauma

An abnormal suppression of the immune system linked to the onset of numerous diseases has been associated with poor functional regeneration of traumatic bone injuries.

18 Feb 2021

How has 3D printing come to the aid of healthcare during the COVID-19 pandemic?

In the study, published in the journal Emergent Materials, the researchers identified the role of 3D printing in COVID-19. During the pandemic, over 100 various 3D printable PPE designs have been used.

18 Feb 2021

Biomedical engineer receives NASA grant to find ways to keep astronauts' bones strong in space

Extended time in space weakens astronauts' bones, so scientists are working to better understand how bone senses and responds to the usual forces placed upon it with the goal of keeping their bones strong.

18 Feb 2021

A glycan controls how SARS-CoV-2’s spike protein opens, study finds

Using simulations, a team of researchers in the U.S. found that the glycan at position N343 of the SARS-CoV-2 spike protein’s receptor-binding domain (RBD) helps in its opening. A mechanism that aids its binding to the host cell receptor.

18 Feb 2021

Endothelial SARS-CoV-2 infection induces proinflammatory responses without supporting viral amplification, finds study

A team of scientists from Australia and Brazil recently investigated the involvement of endothelial cells in the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

18 Feb 2021

SARS-CoV-2 D614G mutation associated with lower antibody binding

The onset of the COVID-19 pandemic has brought about an international effort to uncover the biology of its causative agent, SARS-CoV-2, and to develop effective and safe antivirals to contain and treat the infection. A new study by a team of researchers in France and Sweden discusses one such study, exploring the relative immunogenicity of the three main structural proteins of the virus.

18 Feb 2021

Medical Science News

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

Molecular modeling helps identify the binding site of antidepressantss

Person in the midst of vivid dream can engage in real-time communication

Inhibitors to target SARS-CoV-2 viral protein display strong antiviral activity in transgenic mouse model

Specific cell-to-cell communication associated with progression of gastrointestinal stromal tumors

Immune response to SARS-CoV-2 may be limited by a set of genes

Human brain adapts to loss of sensory information by tapping into visual cues

Study shows positive correlation between cardiorespiratory fitness and cognitive health in preschoolers

Polycomb complexes found to be essential for proper skin development

Could measles virus vectors be used for a new COVID-19 vaccine?

Researchers discover potential new way to target pancreatic tumors with high IFN signaling

Early immunosuppressive biomarkers could predict bone regeneration after trauma

How has 3D printing come to the aid of healthcare during the COVID-19 pandemic?

Biomedical engineer receives NASA grant to find ways to keep astronauts' bones strong in space

A glycan controls how SARS-CoV-2’s spike protein opens, study finds

Endothelial SARS-CoV-2 infection induces proinflammatory responses without supporting viral amplification, finds study

SARS-CoV-2 D614G mutation associated with lower antibody binding

Study forecasts post-COVID-19 hospital activity among children and young people in England

How have COVID-19 pandemic school closures impacted the health of children globally?

Divergent brain activity leads to better memory performance

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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