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New lab-on-a-chip can process and present results rapidly

The chip, developed at Imperial College London and known as TriSilix, is a 'micro laboratory' which performs a miniature version of the polymerase chain reaction (PCR) on the spot. PCR is the gold-standard test for detecting viruses and bacteria in biological samples such as bodily fluids, faeces, or environmental samples.

2 Dec 2020

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

A new study has found that particulate matter (PM) plays a role in providing surfaces for SARS-CoV-2 transmission and interaction, enabling fomite transmission through deposition.

2 Dec 2020

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

A team of researchers at the University of Hong Kong has identified a panel of SARS-CoV-2 variants, called Del-mut, which contains a deletion in the S1/S2 junction. Upon investigating one of the deleted variants in animal models, they found that Del-mut-1 is attenuated in its ability to cause disease or pathological changes.

2 Dec 2020

Study: Maternal omega-3 deficiency can alter the development of neuronal networks in offspring

Omega-3 fatty acids are essential, necessarily supplied by the diet and indispensable to brain development.

2 Dec 2020

Study: Tumors with high TMB tend to respond better to immune checkpoint inhibitors

Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs.

2 Dec 2020

Study: Integrating palliative care earlier in care trajectory benefits COVID-19 patients

Critical care nurses are ideally positioned to drive full integration of palliative care into the care of all patients who are seriously ill, including patients with COVID-19, according to an article published in the December issue of Critical Care Nurse (CCN).

2 Dec 2020

CNRS develops new patented technique that reveals energy status of cells

A procedure that may help personalise anticancer therapies has just been developed by the CNRS, INSERM, and Aix-Marseille University scientists at the Centre d'Immunologie de Marseille-Luminy, in association with colleagues from the University of California San Francisco and the Marseille Public University Hospital System (AP-HM), with support from Canceropôle Provence-Alpes-Côte d'Azur.

2 Dec 2020

Scientists develop new technique to measure tissue oxygen levels

Tissue oxygenation is a measure of the oxygen level in biological tissue and is a useful clinical biomarker for tissue viability. Abnormal levels may indicate the presence of conditions such as sepsis, diabetes, viral infection, or pulmonary disease, and effective monitoring is important for surgical guidance as well as medical care.

2 Dec 2020

Novel method for creating chemical reactions could unlock many new applications

Scientists have broken the rules of enzyme engineering to unlock a new method for creating chemical reactions that could unlock a wide range of new applications - from creating new drugs to food production.

2 Dec 2020

Researchers develop telomerase gene therapy for treating different pathologies

After several years of research and many joint scientific publications, molecular biologists Maria Blasco (National Cancer Research Centre, CNIO) and Fàtima Bosch (Universitat Autònoma de Barcelona, UAB) have developed a telomerase gene therapy for the treatment of different pathologies related to shortening telomeres and, therefore, ageing.

2 Dec 2020

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Immunotherapies have transformed the landscape of cancer treatment by allowing physicians to alter or augment patients' immune response to better attack malignant tumors.

2 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

Novel ALS study effectively visualizes neuroinflammation

A novel ALS (amyotrophic lateral sclerosis) study has pooled data from multiple sites to effectively visualize neuroinflammation, which is key to developing drugs to treat the disease.

2 Dec 2020

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

If there is a silver lining in cancer's chaotic biology, it's that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

2 Dec 2020

Researchers devise new molecular imaging strategy to observe the sperm selection process

A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way.

2 Dec 2020

New, improved probes could make it easier to validate rapid COVID-19 diagnostic tests

Nanoengineers at the University of California San Diego have developed new and improved probes, known as positive controls, that could make it easier to validate rapid, point-of-care diagnostic tests for COVID-19 across the globe.

2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Reducing the delay in neurofeedback can increase the efficacy of training

HSE University scientists have for the first time in the world investigated the impact of delayed reinforcement signals in neurofeedback (NFB) training.

2 Dec 2020

Previously uncharacterized protein regulates mitochondrial NAD transporter

For their growth, cells need various nutrients and vitamins. So-called solute carriers (SLC), proteins that can transport such substances across the boundaries of cellular membranes, play a central role in metabolism.

1 Dec 2020

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

A repurposed mouse model can develop symptoms of both severe COVID-19 (lung damage, blood clots, abnormal blood vessels, and death) and also of milder disease, including loss of the sense of smell, according to a recent University of Iowa study published in Nature.

1 Dec 2020

Medical Science News

New lab-on-a-chip can process and present results rapidly

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

Study: Maternal omega-3 deficiency can alter the development of neuronal networks in offspring

Study: Tumors with high TMB tend to respond better to immune checkpoint inhibitors

Study: Integrating palliative care earlier in care trajectory benefits COVID-19 patients

CNRS develops new patented technique that reveals energy status of cells

Scientists develop new technique to measure tissue oxygen levels

Novel method for creating chemical reactions could unlock many new applications

Researchers develop telomerase gene therapy for treating different pathologies

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Novel ALS study effectively visualizes neuroinflammation

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

Researchers devise new molecular imaging strategy to observe the sperm selection process

New, improved probes could make it easier to validate rapid COVID-19 diagnostic tests

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

Reducing the delay in neurofeedback can increase the efficacy of training

Previously uncharacterized protein regulates mitochondrial NAD transporter

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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