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Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer.

7 Dec 2020

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

B-cell lymphoma and leukemias (BCL) are a diverse set of malignancies. While the genomic landscape of many BCL subtypes has been described, genomic ancestry has rarely been explored.

6 Dec 2020

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial.

6 Dec 2020

COVID-19 pandemic underscores racial inequalities in US: a Michigan case study

A team of researchers has explored how the coronavirus disease 2019 (COVID-19) pandemic has disproportionately affected Black Americans.

6 Dec 2020

Blood type not associated with the effects of plant-based diet

A study published in the Journal of the Academy of Nutrition and Dietetics by researchers with the Physicians Committee for Responsible Medicine--a nonprofit of 12,000 doctors--debunks the "blood type diet" by finding that blood type was not associated with the effects of a plant-based diet on body weight, body fat, plasma lipid concentrations, or glycemic control.

5 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

Traveling in passenger cars with windows open is the safest way to prevent COVID-19 transmission

A new series of computational fluid dynamics simulations suggests that, for two people who must travel together in the same passenger car, the safest way to prevent possible transmission of COVID-19 in such a risky, enclosed environment is to do so with all four windows down and the passenger seated as far as possible from the driver, in the rear seat on the opposite side.

5 Dec 2020

Mysterious particle found in the blood of people with sepsis

Researchers at La Jolla Institute for Immunology have found that people with sepsis have never-before-seen particles in their blood.

5 Dec 2020

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Since the novel coronavirus emerged at the end of last year, scientists around the world -- including Beth Israel Deaconess Medical Center (BIDMC) immunologist Dan Barouch, MD, PhD -- have been developing vaccines to protect against COVID-19 and to put an end to the global pandemic.

5 Dec 2020

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease.

5 Dec 2020

Scientists highlight lack of evidence linking the consumption of live microbes to better health

Many everyday foods--from yogurt and other fermented foods to fresh fruits and vegetables--contain live microorganisms.

5 Dec 2020

Missing link between stress and infertility found

Otago researchers have found the "missing link between stress and infertility".

5 Dec 2020

Biochemical cascade in the brain leads to the destruction of synapses in Alzheimer's

A new study on Alzheimer's disease by Scripps Research scientists has revealed a previously unknown biochemical cascade in the brain that leads to the destruction of synapses, the connections between nerve cells that are responsible for memory and cognition.

5 Dec 2020

TMDU researchers develop new method of making dental materials easier to remove

Tokyo Medical and Dental University researchers report a cross-linker for dental cement that breaks down under UV light, making treatments easier to reverse.

4 Dec 2020

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Affecting almost 600,000 people worldwide every year, and with only a 50% survival rate, oral squamous cell carcinoma (OSCC) is one of the more common and deadly forms of cancer.

4 Dec 2020

COVID-19 herd immunity threshold far higher than previously thought, say researchers

Researchers in the US have re-analyzed the data on herd immunity from spring 2020 from Europe. Their study shows that the herd immunity threshold is much higher than earlier speculated.

4 Dec 2020

Is mask-wearing effective in preventing SARS-CoV-2 transmission?

UK-based researchers released the findings of their review of the efficacy of the face coverings and masks in preventing transmission of coronavirus disease 2019 (COVID-19).

4 Dec 2020

People with vitamin D deficiency at higher risk of severe COVID-19, says study

A new study has revealed that vitamin D deficient patients are more likely to experience severe COVID-19.

4 Dec 2020

The effect of COVID-19 lockdowns on children's health: A UK case study

UK-based researchers have explored how national lockdown has changed young children's everyday activities, eating and sleep habits. They found that children's activity, screen time, eating, and sleep routines have been disrupted during the "stay-at-home" order in the United Kingdom.

4 Dec 2020

Medical Science News

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

COVID-19 pandemic underscores racial inequalities in US: a Michigan case study

Blood type not associated with the effects of plant-based diet

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Traveling in passenger cars with windows open is the safest way to prevent COVID-19 transmission

Mysterious particle found in the blood of people with sepsis

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

Scientists highlight lack of evidence linking the consumption of live microbes to better health

Missing link between stress and infertility found

Biochemical cascade in the brain leads to the destruction of synapses in Alzheimer's

TMDU researchers develop new method of making dental materials easier to remove

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

COVID-19 herd immunity threshold far higher than previously thought, say researchers

Is mask-wearing effective in preventing SARS-CoV-2 transmission?

People with vitamin D deficiency at higher risk of severe COVID-19, says study

The effect of COVID-19 lockdowns on children's health: A UK case study

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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