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Researchers uncover an active role of glycans in SARS-CoV-2 spike protein

As the COVID-19 pandemic rages on, researchers are working overtime to develop vaccines and therapies to thwart SARS-CoV-2, the virus responsible for the disease Many efforts focus on the coronavirus spike protein, which binds the angiotensin-converting enzyme 2 (ACE2) on human cells to allow viral entry.

24 Sep 2020

Researchers develop 'Trojan horse' approach to destroy cancer cells

Cancer cells are killed in lab experiments and tumour growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct, a research team at the Nanyang Technological University, Singapore (NTU Singapore) has found.

23 Sep 2020

Overactivation of fructose made in the brain may drive Alzheimer's disease

New research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by the overactivation of fructose made in the brain.

23 Sep 2020

Study finds spectrum of genes responsible for inherited hearing loss in Israeli Jewish families

Until now, seven genes were known to be involved in hearing loss in Israel's Jewish population. A new study led by Zippora Brownstein, PhD, and Prof. Karen Avraham from the Sackler Faculty of Medicine at Tel Aviv University has found that 32 genes are responsible for inherited hearing loss in Israeli Jewish families.

23 Sep 2020

Dextran sulphate-induced tau assemblies cause tau propagation in non-transgenic mice

Accumulation of assembled tau protein in the central nervous system is characteristic of Alzheimer's disease and several other neurodegenerative diseases, called tauopathies.

23 Sep 2020

Chaperone-mediated autophagy could be a new therapeutic target for spinocerebellar ataxia

A research team from Kumamoto University, Japan has developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated autophagy (CMA) in cerebellar neurons.

23 Sep 2020

Late-life depression not linked with increased amyloid deposits in the brain

Depression in elderly people can include symptoms such as memory loss, making it hard to distinguish from the early stages of Alzheimer's disease and other types of dementia.

23 Sep 2020

Intensive physical exercise session improves memory

If sport is good for the body, it also seems to be good for the brain. By evaluating memory performance following a sport session, neuroscientists from the University of Geneva demonstrate that an intensive physical exercise session as short as 15 minutes improves memory, including the acquisition of new motor skills.

23 Sep 2020

ALS and FTLD result from reduced transportation of messenger RNA

The lack of protein TDP-43 in two neurodegenerative diseases is shown to prevent neuron growth via failed transport of RNA and subsequent absence of protein synthesis in axons

23 Sep 2020

Research shows how the brain balances emotion and cognition

Navigating through life requires balancing emotion and reason, a feat accomplished by the brain region “area 32” of the anterior cingulate cortex.

23 Sep 2020

New technique helps visualize the mechanical forces of cells at the molecular level

Scientists have developed a new technique using tools made of luminescent DNA, lit up like fireflies, to visualize the mechanical forces of cells at the molecular level.

23 Sep 2020

Targeted treatment for systemic lupus erythematosus

A team of researchers from Charité - Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus.

22 Sep 2020

New lactic acid bacteria can be used to make camel milk products safer

A research project headed by the Technical University of Denmark, DTU, has come up with the formula for a freeze-dried starter culture that African camel milk farmers can use to make safe, fermented milk products.

22 Sep 2020

Study shows key genetic differences in ADHD between African American and Caucasian children

Researchers from Children's Hospital of Philadelphia have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition.

22 Sep 2020

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Researchers from Critical Analytics for Manufacturing Personalized-Medicine, an interdisciplinary research group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have been awarded Intra-CREATE grants from the National Research Foundation Singapore to help support research on retinal biometrics for glaucoma progression and neural cell implantation therapy for spinal cord injuries.

22 Sep 2020

Spider venom peptide could help stop pain in irritable bowel syndrome

Their study titled, "A spider-venom peptide with multi-target activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome," is published in the latest issue of the journal Pain.

22 Sep 2020

Existence of brain-first and body-first Parkinson’s disease subtypes

Although the name may suggest otherwise, Parkinson's disease is not one but two diseases, starting either in the brain or in the intestines.

22 Sep 2020

Avid gamers before adolescence perform better with working memory tasks years later

A number of studies have shown how playing video games can lead to structural changes in the brain, including increasing the size of some regions, or to functional changes, such as activating the areas responsible for attention or visual-spatial skills.

22 Sep 2020

Study shows how autoimmune diseases may be targeted using Treg-based cellular therapies

In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

22 Sep 2020

Diabetes leads to drastic reduction in the kidney's potential to clean itself

The kidneys often become bulky and dysfunctional in diabetes, and now scientists have found that one path to this damage dramatically reduces the kidney's ability to clean up after itself.

22 Sep 2020

Medical Science News

Researchers uncover an active role of glycans in SARS-CoV-2 spike protein

Researchers develop 'Trojan horse' approach to destroy cancer cells

Overactivation of fructose made in the brain may drive Alzheimer's disease

Study finds spectrum of genes responsible for inherited hearing loss in Israeli Jewish families

Dextran sulphate-induced tau assemblies cause tau propagation in non-transgenic mice

Chaperone-mediated autophagy could be a new therapeutic target for spinocerebellar ataxia

Late-life depression not linked with increased amyloid deposits in the brain

Intensive physical exercise session improves memory

ALS and FTLD result from reduced transportation of messenger RNA

Research shows how the brain balances emotion and cognition

New technique helps visualize the mechanical forces of cells at the molecular level

Targeted treatment for systemic lupus erythematosus

New lactic acid bacteria can be used to make camel milk products safer

Study shows key genetic differences in ADHD between African American and Caucasian children

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Spider venom peptide could help stop pain in irritable bowel syndrome

Existence of brain-first and body-first Parkinson’s disease subtypes

Avid gamers before adolescence perform better with working memory tasks years later

Study shows how autoimmune diseases may be targeted using Treg-based cellular therapies

Diabetes leads to drastic reduction in the kidney's potential to clean itself

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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