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Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

In a promising study by US researchers, the receptor-binding domain (RBD) and stabilized spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were displayed on nanoparticles as vaccine antigens and elicited potent immune responses.

16 Sep 2020

Non-invasive test of brain function could predict treatment response in depressed teen girls

The risk of developing major depressive disorder (MDD) surges during adolescence-particularly for girls. Cognitive behavioral therapy (CBT) can be an effective treatment, but only about half of girls diagnosed with depression show significant improvement.

16 Sep 2020

Study uncovers new markers present on melanoma tumors

A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.

16 Sep 2020

Carotid artery calcification seen in radiographs linked with coronary artery disease, oral infections

The calcification of the carotid artery is a sign of advanced arteriosclerosis, which may be associated with chronic coronary artery disease (CAD) and can lead to death. Such calcification can be seen in regular oral panoramic radiography.

16 Sep 2020

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy.

16 Sep 2020

Study provides valuable insights on effects of APOE gene on health and disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labelled as 'bad' are not always what they seem.

16 Sep 2020

Researchers develop protein-based biosensor for multiplex imaging of neurotransmitter

In 2018, Lin Tian and her team at UC Davis Health developed dLight1, a single fluorescent protein-based biosensor. This family of highly specific sensors detects dopamine, a hormone released by neurons to send signals to other nerve cells.

16 Sep 2020

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome -- the trillions of microbes living inside the digestive system that regulate various bodily functions.

16 Sep 2020

New mechanism could explain how immune cancer cells migrate in various fluid-filled niches

Human white blood cells, known as leukocytes, swim using a newly described mechanism called molecular paddling, researchers report in the September 15th issue of Biophysical Journal.

16 Sep 2020

Researchers receive NIH grant to evaluate the impact of COVID-19 on heart disease patients

A University of Illinois Chicago research study on how to improve care for heart disease patients struggling with hopelessness has been supplemented by the National Institutes of Health, or NIH, to determine whether the study intervention called "Heart Up!" limits the negative impact of COVID-19 shelter-in-place and physical distancing measures on health outcomes.

16 Sep 2020

New process enriches omega-3 fatty acid content in dietary supplements

A new study, co-led by University of Cincinnati researchers, describes the development of a refining process that scientists deem a superior method to help produce better dietary omega-3 health and dietary supplements containing fish oil.

16 Sep 2020

Study highlights role of specific protein in the mass production of antibodies

Antibodies play a fundamental role in medicine, and antibody-mediated immune response is the ultimate target in the quest for a vaccine to defeat the current pandemic.

16 Sep 2020

Treatment with a cannabinoid prevented the development of colon cancers in mice

Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are caused by unrestrained inflammation of the gastrointestinal tract.

15 Sep 2020

Study reveals damaging role of immune system in severe brain infection

A new study has detailed the damaging role played by the immune system in a severe brain condition most commonly caused by the cold sore virus.

15 Sep 2020

Study explores how sleep affects people's reaction to both stressful and positive events

New research from UBC finds that after a night of shorter sleep, people react more emotionally to stressful events the next day--and they don't find as much joy in the good things.

15 Sep 2020

Newly identified mechanism regulates the distensibility of the heart

A healthy heart beats 50 to 100 times a minute and pumps 8,000 litres of blood around our body every day. A precondition for this function is the elasticity of the cardiac walls, which dilate as blood flows in (diastole) and contract again as the blood flows out (systole).

15 Sep 2020

New biomarker can reliably predict aggressiveness of biliary tract cancer

The cancer called biliary tract cancer (BTC) is not the most widespread form of cancer. In western countries, about 1.6 in 100.000 gets the diagnose every year. It is, however, a very aggressive form of cancer.

15 Sep 2020

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Fondazione Santa Lucia IRCCS, and Università Cattolica del Sacro Cuore in Rome have shown that pharmacological (drug) correction of the content of extracellular vesicles released within dystrophic muscles can restore their ability to regenerate muscle and prevent muscle scarring (fibrosis).

15 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020

Scientists unlock crucial molecular details regarding tau's activity

Frontotemporal lobar degeneration (FTLD) is a type of dementia that appears earlier in life than Alzheimer's disease (AD).

15 Sep 2020

Medical Science News

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

Non-invasive test of brain function could predict treatment response in depressed teen girls

Study uncovers new markers present on melanoma tumors

Carotid artery calcification seen in radiographs linked with coronary artery disease, oral infections

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Study provides valuable insights on effects of APOE gene on health and disease

Researchers develop protein-based biosensor for multiplex imaging of neurotransmitter

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

New mechanism could explain how immune cancer cells migrate in various fluid-filled niches

Researchers receive NIH grant to evaluate the impact of COVID-19 on heart disease patients

New process enriches omega-3 fatty acid content in dietary supplements

Study highlights role of specific protein in the mass production of antibodies

Treatment with a cannabinoid prevented the development of colon cancers in mice

Study reveals damaging role of immune system in severe brain infection

Study explores how sleep affects people's reaction to both stressful and positive events

Newly identified mechanism regulates the distensibility of the heart

New biomarker can reliably predict aggressiveness of biliary tract cancer

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

Scientists unlock crucial molecular details regarding tau's activity

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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