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Study: NTRK fusions are far more frequently seen in pediatric tumors

In a large study of pediatric cancer patients, researchers from Children's Hospital of Philadelphia have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors.

16 Jan 2021

Simple blood test can predict which COVID-19 patients are at high risk of severe disease

One of the most vexing aspects of the COVID-19 pandemic is doctors' inability to predict which newly hospitalized patients will go on to develop severe disease, including complications that require the insertion of a breathing tube, kidney dialysis or other intensive care.

15 Jan 2021

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people.

15 Jan 2021

Severe COVID-19 linked to genetic make-up of both host and virus, say researchers

A recent study conducted by a team of international scientists has revealed that the infectivity and pathogenicity of SARS-CoV-2 strongly depend on the genetic background of both the virus and the host.

15 Jan 2021

White-tailed deer susceptible to SARS-CoV-2 infection, study finds

A team of scientists recently demonstrated that white-tailed deer are highly susceptible to SARS-CoV-2 infection. Moreover, the infected animals are capable of transmitting the virus to their non-infected counterparts via indirect contact.

15 Jan 2021

Image-based deep learning haplotype-guided study maps the global adaptation of SARS-CoV-2

A new study used deep learning with image recognition technology to trace the emergence of variants with increased viral fitness. Higher fitness leads to rapid expansion of these lineages in the areas where they are introduced. This type of study could facilitate the development of more effective antibodies and vaccines to help contain the pandemic.

15 Jan 2021

What are the SARS-CoV-2 exposure risks for workers on mink farms?

A new study reports on the risk of COVID-19 among workers on these farms, and in the communities living around such farms.

15 Jan 2021

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

A new study reports the antiviral potential of peptides against SARS-CoV-2's spike protein.

15 Jan 2021

Can cloth masks protect healthcare professionals from SARS-CoV-2?

Given the global scarcity of surgical masks, a recent review study examines this issue - dealing with the potential use of cloth masks in healthcare scenarios.

15 Jan 2021

Study reports promising new monoclonal antibody against SARS-CoV-2’s spike protein

An encouraging new study describes a promising new therapeutic antibody that shows potent neutralizing activity against SARS-CoV-2, the causative agent of COVID-19.

15 Jan 2021

Study to examine if changing mealtimes could reduce the risk of Type 2 diabetes

An innovative new study is set to examine if changing our mealtimes to earlier or later in the day could reduce the risk of developing Type 2 diabetes.

15 Jan 2021

Researchers to study potential treatment for limb dysfunction in patients with chronic spinal cord injury

Ghaith Androwis, PhD, and Steven Kirshblum, MD, received a grant from BrainQ Technologies to study a potential treatment for arm and hand dysfunction in individuals with chronic spinal cord injury.

15 Jan 2021

Study may lead to novel synthetic drugs to combat bacterial infections

Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections.

15 Jan 2021

Meniscal and mechanical symptoms do not predict findings on knee arthroscopy

Orthopaedic surgeons have traditionally been taught that certain types of knee symptoms indicate damage to specialized structures called the menisci.

15 Jan 2021

Scientists make new discovery in the quest for novel antibiotics

Scientists who highlighted the bug-busting properties of bacteria in Northern Irish soil have made another exciting discovery in the quest to discover new antibiotics.

15 Jan 2021

Newly discovered biochemical pathway can protect cells from ferroptosis

The hallmarks of cancer include rapid cell-reproduction and metabolic activity. But these processes also lead to increased cellular stress and oxidation, and the risk of cell death.

15 Jan 2021

New probes allow scientists to see quadruple-helix DNA in living human cells

New probes allow scientists to see four-stranded DNA interacting with molecules inside living human cells, unravelling its role in cellular processes.

14 Jan 2021

New cellular pathway limits growth and spread of brain tumors

Researchers at McGill University have identified a new cellular pathway that limits the growth and spread of brain tumors by controlling the recycling of cell surface receptor proteins.

14 Jan 2021

What are the dynamics of SARS-CoV-2 transmission inside an aircraft cabin?

A team of US scientists has recently evaluated the risk of SARS-CoV-2 infection among passengers present inside an aircraft cabin. The findings suggest that the risk of airborne viral transmission is minimal during long-duration flights.

14 Jan 2021

Scientists identify animal model to study human musculoskeletal aging

There are many components to aging, both mental and physical. When it comes to the infrastructure of the human body - the musculoskeletal system that includes muscles, bones, tendons and cartilage - age-associated decline is inevitable, and the rate of that decline increases the older we get.

14 Jan 2021