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Researchers develop saliva testing method for SARS-CoV-2 using robotic RNA extraction

Researchers have developed an automated method of RNA extraction from saliva samples to allow faster processing times and high test sensitivity. Saliva testing could be used as an alternative to swab testing for coronavirus disease 2019 (COVID-19) surveillance.

12 Jan 2021

Could Vitamin D be an effective adjuvant to help mitigate the COVID-19 pandemic?

As the coronavirus pandemic continues to wreak havoc across the globe, there is a dire need for effective and safe therapeutics and vaccines. Overall, the pandemic has infected more than 90.87 million people and taken more 1.94 million lives.

12 Jan 2021

Headache as COVID-19 symptom could indicate milder disease, study finds

Researchers at the Hospital Universitario de La Princes in Madrid, Spain, found that patients with COVID-19 who developed headaches as an early symptom of infection had a milder illness and less risk of death.

12 Jan 2021

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Oncotarget recently published "Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy" which reported that Chimeric antigen receptor T cell therapies, and adoptive cell therapy in general, represent one of the most promising anti-cancer strategies.

12 Jan 2021

Study: Anal intraepithelial neoplasia is a precursor lesion for anal squamous cell carcinomas

Oncotarget recently published "PD-1/PD-L1 expression in anal squamous intraepithelial lesions" which reported that the presence and distribution of CD8 lymphocytes and the presence of PD-1 lymphocytes and PD-L1 epithelial cells were assessed.

12 Jan 2021

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

12 Jan 2021

Researchers study the behavior of regulatory T cells to understand periodontal disease

In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens to the regulatory mechanisms that protect bone?

12 Jan 2021

Researchers identify a new link between seizures and connexin 36 deficiency

For the brain to learn, retain memories, process sensory information, and coordinate body movements, its groups of nerve cells must generate coordinated electrical signals. Disorder in synchronous firing can impair these processes and, in extreme cases, lead to seizures and epilepsy.

12 Jan 2021

Rice model could help clinicians personalize hip joints

Rice University engineers hope to make life better for those with replacement joints by modeling how artificial hips are likely to rub them the wrong way.

11 Jan 2021

Polymer patch provides controlled release of drugs for post-operative pain management

A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away.

11 Jan 2021

Study uncovers strong links between a person's diet, gut microbes and health

Diets rich in certain plant-based foods are linked with the presence of gut microbes that are associated with a lower risk of developing conditions such as obesity, type 2 diabetes and cardiovascular disease, according to recent results from a large-scale international study that included researchers from King's College London, the Harvard T.H. Chan School of Public Health, Massachusetts General Hospital, the University of Trento, Italy, and health science start-up company ZOE.

11 Jan 2021

Trinity researchers discover key mechanism underlying bacterial skin colonization in atopic dermatitis

Researchers from Trinity College Dublin have discovered a key mechanism underlying bacterial skin colonization in atopic dermatitis, which affects millions around the globe.

11 Jan 2021

Study finds association between severity of COVID-19 and shorter telomeres

Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.

11 Jan 2021

Over half of COVID-19 cases are spread by asymptomatic carriers, CDC study finds

In a new study conducted by researchers at the U.S. Centers for Disease Control and Prevention (CDC), over half of SARS-CoV-2 infections are believed to be transmitted asymptomatically.

11 Jan 2021

Sustained immune response memory detected in recovered COVID-19 patients

A team of researchers at the University of Washington School of Medicine has found that people who had mild COVID-19 developed a multi-layered immune response against SARS-Cov-2. The researchers detected neutralizing antibodies against the virus for at least three months after recovering from the infection.

11 Jan 2021

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

A recent study has found that extracellular vimentin can bind to SARS-CoV-2 spike protein in vitro, and antibodies against vimentin can decrease virus infectivity by up to 80%. This suggests vimentin could aid the virus’s binding to host cells and help in infection.

11 Jan 2021

Study: 20% of glioblastomas are fueled by overactive mitochondria

A new study has found that up to 20% of glioblastomas--an aggressive brain cancer--are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.

11 Jan 2021

Study explores the ability of laypeople to visually assess severity of blood loss

When an accident occurs, the reactions of bystanders are important. Researchers have studied whether laypeople realize the severity of the situation when someone in their proximity begins to bleed, and whether they can estimate how much the person is bleeding.

11 Jan 2021

Could Ivermectin be an effective antiviral against SARS-CoV-2?

A double-blind, randomized, placebo-controlled clinical trial has recently demonstrated that Ivermectin, an anti-parasitic drug, can reduce in-hospital mortality rate of COVID-19 patients.

11 Jan 2021

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

Scientists from Germany and China recently conducted a large meta-analysis using transcriptome data of SARS-CoV-2 to evaluate the routes of viral entry and the characteristics of innate immune responses induced by SARS-CoV-2 infection.

11 Jan 2021

Medical Science News

Researchers develop saliva testing method for SARS-CoV-2 using robotic RNA extraction

Could Vitamin D be an effective adjuvant to help mitigate the COVID-19 pandemic?

Headache as COVID-19 symptom could indicate milder disease, study finds

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Study: Anal intraepithelial neoplasia is a precursor lesion for anal squamous cell carcinomas

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Researchers study the behavior of regulatory T cells to understand periodontal disease

Researchers identify a new link between seizures and connexin 36 deficiency

Rice model could help clinicians personalize hip joints

Polymer patch provides controlled release of drugs for post-operative pain management

Study uncovers strong links between a person's diet, gut microbes and health

Trinity researchers discover key mechanism underlying bacterial skin colonization in atopic dermatitis

Study finds association between severity of COVID-19 and shorter telomeres

Over half of COVID-19 cases are spread by asymptomatic carriers, CDC study finds

Sustained immune response memory detected in recovered COVID-19 patients

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

Study: 20% of glioblastomas are fueled by overactive mitochondria

Study explores the ability of laypeople to visually assess severity of blood loss

Could Ivermectin be an effective antiviral against SARS-CoV-2?

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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