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St. Jude scientists create O-PDX models for pediatric brain tumor research

Scientists at St. Jude Children's Research Hospital have created orthotopic patient-derived xenograft (O-PDX) models representing a variety of pediatric brain tumor types.

23 Jun 2020

Woman's immune system behaves differently between first and later pregnancies

Among the holy quests of serious and mysterious medical challenges that doctors and research scientists strive to vanquish is preventing miscarriages, stillbirth and other pregnancy complications including preterm births.

23 Jun 2020

Research reveals new insights into molecular circuitry controlling cancer growth and spread

Research led by Queen Mary University of London has revealed novel insights into the molecular circuitry controlling cancer cell growth and spread.

23 Jun 2020

Study shows social robot offers new strategies for pain management

Could furry social robots help bolster moods and reduce pain when human to human contact isn't an option, for example, during a pandemic?

23 Jun 2020

Collaboration between human and artificial intelligence has huge potential in medicine

Artificial Intelligence (AI) is increasingly being used in medicine to support human expertise. However, the potential of these applications and the risks inherent in the interaction between human and artificial intelligence has not yet been thoroughly researched.

23 Jun 2020

Research shows tongue microbiome could help diagnose heart failure

Microorganisms on the tongue could help diagnose heart failure, according to research presented today on HFA Discoveries, a scientific platform of the European Society of Cardiology (ESC).1

23 Jun 2020

Defective maintenance puts intestinal health in danger

In order to keep the intestinal mucosa and the entire organism healthy, intestinal epithelial cells have developed various protective functions involving a number of maintenance mechanisms that protect cells from stress.

23 Jun 2020

Researchers discover key protein that can reduce damage caused by heart attack

In a heart attack, a series of biochemical processes leave the heart damaged, much like a car after an accident.

23 Jun 2020

Research shows females use anti-inflammatory T cells to maintain their blood pressure

In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say.

23 Jun 2020

Dire warning on contamination of water and COVID-19 spread

A recent report by scientists in the United Kingdom and Poland and published on the preprint server medRxiv in June 2020 describes the presence of stable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in water for up to 25 days, with the risk of infection by the contaminated water varying by the country’s environment.

22 Jun 2020

Prior infection provides protection against SARS-CoV-2 virus in hamsters

In an animal model for COVID-19 that shares important features of human disease, scientists at the University of Wisconsin–Madison, the University of Tokyo and the Icahn School of Medicine at Mount Sinai show that prior infection with the SARS-CoV-2 virus provides protection against reinfection, and treatment with convalescent serum limits virus replication in their lungs.

22 Jun 2020

Newly discovered Alzheimer's gene may drive earliest brain changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers at Columbia University Irving Medical Center.

22 Jun 2020

Organoids can help provide new level of accuracy in prescribing anti-cancer therapies

Precision medicine, using the power of the human genome to diagnose and treat patients, is about to get even more precise.

22 Jun 2020

Manipulating macrophages could be a viable strategy for treating cancer

Most traditional cancer therapies target either the tumor cells themselves or indiscriminately kill any rapidly dividing cell.

22 Jun 2020

Researchers identify mouse model that mimics HFpEF syndrome in humans

A receptor that plays an essential role in safely clearing chronic unresolved cardiac inflammation may offer new targets for treating an increasing type of heart failure associated with age-related obesity, suggests a preclinical study led by researchers at the University of South Florida Health Heart Institute, Morsani College of Medicine.

22 Jun 2020

Researchers show new way to help the body efficiently repair injuries

By softening a cell's nucleus so that it can squeeze its way through dense connective tissues, a group of researchers believe they've demonstrated a new way to help the body efficiently repair injuries.

22 Jun 2020

Special time-locked encoding mechanism may have evolved for human speech

Humans can effortlessly recognize and react to natural sounds and are especially tuned to speech. There have been several studies aimed to localize and understand the speech-specific parts of the brain, but as the same brain areas are mostly active for all sounds, it has remained unclear whether or not the brain has unique processes for speech processing, and how it performs these processes.

22 Jun 2020

Insight into merits and limitations of direct reprogramming strategies for cardiac regeneration

Direct reprogramming or Transdifferentiation is a way of inducing changes in the cell type from one lineage into another lineage, bypassing pluripotency.

22 Jun 2020

Dust mite allergens activate well-known inflammatory factor to trigger allergies

A research team at MedUni Vienna, working in cooperation with the Johns Hopkins University in Baltimore, has discovered how certain dust mite allergens activate a well-known inflammatory factor - serum amyloid A protein -and can thus "trim" the lung tissue "in the direction of allergy".

22 Jun 2020

New, five-minute urine test measures the health of a person's diet

Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

22 Jun 2020