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Research may help older adults maintain skeletal muscle mass and physical function for longer

Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria.

22 Mar 2020

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

Immunotherapy that involves treating cancer with the body's own immune cells, or those of a matched donor, shows promise in clinical trials for some patients, but not all.

22 Mar 2020

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

A study by investigators at Hospital for Special Surgery has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease.

22 Mar 2020

A review of the literature on acute promyelocytic leukemia

Oncotarget Volume 11, Issue 11 reported that relapsed APL, particularly in the high-risk subset of patients, remains an important clinical problem.

22 Mar 2020

Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Oncotarget Volume 11, Issue 11 reported that at clinical progression, 64 EGFR T790M plasma positive patients were subjected to second line-treatment with osimertinib and strictly monitored during the first month of therapy.

22 Mar 2020

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Oncotarget Volume 11, Issue 11 reported that in order to understand the molecular mechanism of the dependency in MM, the research team examined gene expression changes upon DOT1L inhibition in sensitive and insensitive cell lines and discovered that genes belonging to the endoplasmic reticulum stress pathway and protein synthesis machinery were specifically suppressed in sensitive cells.

22 Mar 2020

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

MingKuan Lin, Research Assistant Professor, INOVA Neuroscience, School of Systems Biology, is working to measure gene expression levels in blood from patients undergoing treatment with buprenorphine for opioid use disorder.

22 Mar 2020

New drug can alleviate the side effects of tricyclic antidepressants

About one in five Danes are affected by depression at some point in their lives. The severe depressions may be treated with the so-called 'tricyclic antidepressants', an antidepressant drug that is more effective than the drugs used for mild and moderate depressions.

22 Mar 2020

Lance Liotta receives $72,000 for collaborative project

Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, received $72,000 from Queensland University of Technology for the project: "The Systems Biochemistry of Adaptation in Cellular Protein Networks." Australian Research Council Future Fellowship (total $784,680).

22 Mar 2020

DFG underlines the need for long-term, knowledge-driven basic research

In view of the coronavirus pandemic, the Deutsche Forschungsgemeinschaft has underlined the need for long-term, knowledge-driven basic research.

21 Mar 2020

Lab-on-chip device to monitor how extracellular matrix responds to disease

Similarly to how a picked lock gives away that someone has broken into a building, the stiffening of a structure surrounding cells in the human body can indicate that cancer is invading other tissue.

21 Mar 2020

Preclinical study characterizes the binding affinity and selectivity of a selective FLT3 inhibitor

Oncotarget Volume 11, Issue 11 reported that in this preclinical study, we characterized the binding affinity and selectivity of quizartinib, a small-molecule inhibitor of FLT3, and AC886, the active metabolite of quizartinib, compared with those of other FLT3 inhibitors.

21 Mar 2020

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

Researchers at the Centro Nacional de Investigaciones Cardiovasculares, working with an international network of scientists, have identified an inflammatory regulatory circuit in the eye controlled by a subtype of endothelial cells, the cells that line the interior of blood vessels.

21 Mar 2020

New technology that “videos” brain activity could one day enhance prosthetics

Researchers have made a brain-machine interface that links the brain to a silicon chip that “films” neural electrical activity.

20 Mar 2020

New UCI-led study reveals how skin cells prepare to heal wounds

Scientists have revealed how skin cells prepare to heal, potentially leading to better understanding of healing within diabetes.

20 Mar 2020

Researchers develop accurate and scalable method to record brain activity

A new method to accurately record brain activity at scale has been developed by researchers at the Crick, Stanford University and UCL.

20 Mar 2020

Genetically modified neurons could enhance function of clinical implants

A team has genetically reprogrammed neurons that could enhance electrical implant function used in various clinical scenarios.

20 Mar 2020

Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms

Organs-on-Chips technology has entered the mainstream and has reached 150 installations for use by researchers across many industries, including 10 of the top 25 biopharmaceutical companies, as well as leading international academic research centers and U.S. government laboratories, including the U.S. FDA through a collaborative agreement and the U.S. Army.

20 Mar 2020

G-FET based biosensors for selective identification of deadly bacteria strains

Using a single atom-thick sheet of graphene to track the electronic signals inherent in biological structures, a team led by Boston College researchers has developed a platform to selectively identify deadly strains of bacteria, an advance that could lead to more accurate targeting of infections with appropriate antibiotics, the team reported in the journal Biosensors and Bioelectronics.

19 Mar 2020

Research provides better understanding of how tremor happens

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital have improved our understanding of how tremor -- the most common movement disorder -- happens, opening the possibility of novel therapies for this condition.

19 Mar 2020

Medical Science News

Research may help older adults maintain skeletal muscle mass and physical function for longer

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

A review of the literature on acute promyelocytic leukemia

Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

New drug can alleviate the side effects of tricyclic antidepressants

Lance Liotta receives $72,000 for collaborative project

DFG underlines the need for long-term, knowledge-driven basic research

Lab-on-chip device to monitor how extracellular matrix responds to disease

Preclinical study characterizes the binding affinity and selectivity of a selective FLT3 inhibitor

CNIC scientists identify inflammatory regulatory circuit controlled by endothelial cells in the eye

New technology that “videos” brain activity could one day enhance prosthetics

New UCI-led study reveals how skin cells prepare to heal wounds

Researchers develop accurate and scalable method to record brain activity

Genetically modified neurons could enhance function of clinical implants

Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms

G-FET based biosensors for selective identification of deadly bacteria strains

Research provides better understanding of how tremor happens

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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