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Diet affects sperm and the health of offspring

A new study published in the journal Molecular Cell, in March 2020, reports that parental diet is a crucial factor in the future metabolic health of the offspring.

19 Mar 2020

Researchers find key molecule that helps neurons maintain information in working memory

Working memory, the ability to hold a thought in mind even through distraction, is the foundation of abstract reasoning and a defining characteristic of the human brain.

19 Mar 2020

Research may pave the way to developing effective treatments for puerperal sepsis

Puerperal sepsis, also known as childbed fever, is the leading cause of maternal deaths. In this novel study in The American Journal of Pathology, published by Elsevier, scientists report on the discovery of group A streptococcus (GAS) surface proteins involved in female reproductive tract infections such as puerperal sepsis that may pave the way to developing vaccines and more effective treatments.

19 Mar 2020

Substances linked to bladder cancer found in the urine of e-cigarette users

An analysis of evidence from multiple scientific studies found six substances that have a strong link to bladder cancer in the urine of people who had used electronic cigarettes and sometimes other tobacco products, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and NYU Langone Health reported.

19 Mar 2020

Dietary sugar has negative impact on health independent of obesity

Sugar-rich diets have a negative impact on health independent of obesity reports a new study led by the MRC London Institute of Medical Sciences, UK.

19 Mar 2020

Study offers new insight into genetic alterations associated with osteosarcoma

A study by researchers at the National Cancer Institute, part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common cancerous bone tumor of children and adolescents.

19 Mar 2020

Revolutionary technology could help identify more effective cancer drug combinations

A revolutionary new technology has been applied to reveal the inner workings of individual cancer cells - potentially identifying more effective treatment combinations for people with cancer.

19 Mar 2020

Bacteria-trapping protein may contribute to breast cancer metastasis

The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular Cancer Research, a journal of the American Association for Cancer Research.

19 Mar 2020

Identification of 'Hodor' in the gut lining highlights potential way to curb mosquito populations

The identification of an insect-specific metal-sensing receptor in the gut lining highlights a possible new way to curb populations of disease-transmitting insects such as mosquitoes.

18 Mar 2020

Singapore researchers find common therapeutic vulnerability for a deadly blood cancer

CML is a blood cancer that can be controlled by continuously taking an expensive type of medicine called a tyrosine kinase inhibitor (TKI). In almost all patients, stopping TKI treatment results in recurrence of CML.

18 Mar 2020

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

The cover for issue 11 of Oncotarget features Figure 6, "Effects of AZD8186 in combination with anti-PD1 on syngeneic models," by Owusu-Brackett, et al.

18 Mar 2020

Viewpoint: Could infectious pathogens play a role in Alzheimer's disease?

For researchers investigating Alzheimer's Disease (AD), a devastating neurodegenerative illness afflicting close to 6 million Americans, it is the best and worst of times.

18 Mar 2020

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

A research team led by Children's National Hospital faculty was able to "rescue" a pre-clinical model of fetal alcohol spectrum disorder in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.

18 Mar 2020

C-Path and Lundbeck join hands to improve scientific community's insight in Alzheimer's

The Critical Path Institute and H. Lundbeck A/S are proud to announce that they will work together to significantly improve the scientific community's insight in Alzheimer's disease through Lundbeck's contribution of a unique set of clinical trial data from more than 2,500 AD patients to the Critical Path for Alzheimer's Disease consortium's integrated database for qualified researchers across the globe to access.

18 Mar 2020

Researchers study how changing seasons will affect coronavirus spread

One of the biggest unknowns about the coronavirus is how changing seasons will affect its spread. Physicists from the University of Utah have received the university's first COVID-19-related grant to tackle the question.

18 Mar 2020

Using 'organs-on-a-chip' to study chronic inflammatory diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

18 Mar 2020

Bacterial extracellular vesicles could combat antibiotic resistance

Children's National Hospital researchers for the first time have isolated bacterial extracellular vesicles from the blood of healthy donors, a critical step to better understanding the way gut bacteria communicate with the rest of the body via the bloodstream.

18 Mar 2020

Immune mechanism in the brain appears to play key role in the development of Alzheimer's

An immune reaction in the brain seems to play a major role in the development of Alzheimer's disease. In a way, it "adds fuel to the fire" and apparently causes an inflammation that, in a sense, keeps kindling itself. The study has now been published in the journal Cell Reports.

18 Mar 2020

Novel Alzheimer's risk genes affect microglial response to amyloid-beta

Our DNA determines a large part of our risk for Alzheimer's disease, but it remained unclear how many genetic risk factors contribute to disease.

18 Mar 2020

UCLA researcher awarded NIH grant to study pain-relieving effects of cannabis chemicals

Ziva Cooper, research director of the UCLA Cannabis Research Initiative, has been awarded a $3.9 million grant from the National Center for Complementary and Integrative Health at the NIH to study whether cannabis chemicals called terpenes can reduce the amount of opioid medication a person needs to reduce pain.

18 Mar 2020

Medical Science News

Diet affects sperm and the health of offspring

Researchers find key molecule that helps neurons maintain information in working memory

Research may pave the way to developing effective treatments for puerperal sepsis

Substances linked to bladder cancer found in the urine of e-cigarette users

Dietary sugar has negative impact on health independent of obesity

Study offers new insight into genetic alterations associated with osteosarcoma

Revolutionary technology could help identify more effective cancer drug combinations

Bacteria-trapping protein may contribute to breast cancer metastasis

Identification of 'Hodor' in the gut lining highlights potential way to curb mosquito populations

Singapore researchers find common therapeutic vulnerability for a deadly blood cancer

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

Viewpoint: Could infectious pathogens play a role in Alzheimer's disease?

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

C-Path and Lundbeck join hands to improve scientific community's insight in Alzheimer's

Researchers study how changing seasons will affect coronavirus spread

Using 'organs-on-a-chip' to study chronic inflammatory diseases

Bacterial extracellular vesicles could combat antibiotic resistance

Immune mechanism in the brain appears to play key role in the development of Alzheimer's

Novel Alzheimer's risk genes affect microglial response to amyloid-beta

UCLA researcher awarded NIH grant to study pain-relieving effects of cannabis chemicals

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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