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Jackson Laboratory announces research affiliation, publishes new papers on genes and microbiome

January has been an exciting month at The Jackson Laboratory (JAX). With this surplus of news, we wanted to share three major stories from the past week:

31 Jan 2020

Scientists describe genetic program behind primordial lung progenitors

For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

31 Jan 2020

Long noncoding RNA can protect our metabolism against metabolic complications

Unlike what we commonly refer to as 'genes', these phantom genes or 'Long noncoding RNA' (LncRNAs) do not lead to the production of proteins that our cells, and thus our entire bodies are made of.

31 Jan 2020

A new study reveals the secrets of mucus production that could be applied to cancer biology

The cells that produce mucus are known to be involved in serious health conditions such as asthma, chronic obstructive pulmonary disease, and even cancer.

31 Jan 2020

Researchers provide first insight into innovative approach for diabetes care

The circadian clock system (from Latin "circa diem", about a day) allows the organisms to anticipate periodical changes of geophysical time, and to adjust to these changes. Nearly all the cells in our body comprise molecular clocks that regulate and synchronize metabolic functions to a 24-hour cycle of day-night changes.

31 Jan 2020

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects.

31 Jan 2020

Exercise found to improve video game performance

Time spent playing video games is often seen as time stolen from physical activities. Research has shown that exercise has many physical and cognitive benefits.

31 Jan 2020

Multimodal analysis of tumors could give new insights into treating cancer patients

Melding the genetic and cellular analysis of tumors with how they appear in medical images could give physicians and other cancer therapy specialists new insights into how to best treat patients, especially those with brain cancer, according to a new study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

31 Jan 2020

Modified form of poliovirus shows potential as cancer vaccine in animal studies

A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.

31 Jan 2020

IU researchers receive $3 million NIH grants to study cell functions in the bone marrow

More than $3 million from the National Institutes of Health will allow Indiana University Melvin and Bren Simon Cancer Center researchers to improve understanding of the complex system of how hematopoietic stem cells survive and sustain their function in the bone marrow.

31 Jan 2020

Researchers locate specific mutation in the gene responsible for Chédiak-Higashi syndrome

Humans and animals are made up of trillions of cells, and each cell contains DNA specific to that individual. Therefore, identifying DNA that causes genetic disorders gives researchers and clinicians a better understanding of how to treat inherited diseases and possibly prevent the diseases from being passed down to future generations.

30 Jan 2020

New recommendations to improve survival chances for patients with acute bowel obstruction

A new report has shared recommendations to improve the chance of survival for patients with acute bowel obstruction.

30 Jan 2020

UW creates new integrated center to accelerate development of biomedical discoveries

With $4 million in matching funds from the National Institutes of Health, the University of Washington has created a new integrated center to match biomedical discoveries with the resources needed to bring innovative products to the public and improve health.

30 Jan 2020

Low and high exercise intensities differentially influence brain function, study shows

A new study shows for the first time that low and high exercise intensities differentially influence brain function.

30 Jan 2020

Research uncovers how HIV develops resistance to key drugs

The mechanism behind how HIV can develop resistance to a widely-prescribed group of drugs has been uncovered by new research from the Crick and Dana-Farber Cancer Institute, with the findings opening the door to the development of more effective treatments.

30 Jan 2020

Potential new biomarker for vascular dementia identified

Vascular dementia is caused by a defect on blood flow arrival to the brain, which consequently generates neuronal damage.

30 Jan 2020

Sugary diet can promote periodontal diseases

Sweet soft drinks and lots of sugar increase the risk of both dental cavities and inflammation of the gums - known as periodontal diseases - and if this is the case, then healthy eating habits should be prioritised even more. This is the conclusion of a research result from Aarhus University.

30 Jan 2020

WPI researcher awarded grant for research into leading cause of aortic valve dysfunction

Worcester Polytechnic Institute researcher Kristen Billiar has been awarded a $154,000 grant from the American Heart Association to determine how cell death leads to calcium deposits in heart tissue that cause aortic valves to fail.

30 Jan 2020

Researchers use new technique to improve the ability to model lung diseases

Using a combination of pluripotent stem cells (cells that can potentially produce any cell or tissue type) and machine learning (artificial intelligence that allows computers to learn automatically), researchers have improved how they generate lung cells.

30 Jan 2020

New study lays foundation for next generation aortic grafts

A new study by researchers at McGill University has measured the dynamic physical properties of the human aorta, laying the foundation for the development of grafts capable of mimicking the native behaviour of the human body's largest artery.

30 Jan 2020

Medical Science News

Jackson Laboratory announces research affiliation, publishes new papers on genes and microbiome

Scientists describe genetic program behind primordial lung progenitors

Long noncoding RNA can protect our metabolism against metabolic complications

A new study reveals the secrets of mucus production that could be applied to cancer biology

Researchers provide first insight into innovative approach for diabetes care

New discovery could enable scientists to fine-tune activity of cancer-killing immune cells

Exercise found to improve video game performance

Multimodal analysis of tumors could give new insights into treating cancer patients

Modified form of poliovirus shows potential as cancer vaccine in animal studies

IU researchers receive $3 million NIH grants to study cell functions in the bone marrow

Researchers locate specific mutation in the gene responsible for Chédiak-Higashi syndrome

New recommendations to improve survival chances for patients with acute bowel obstruction

UW creates new integrated center to accelerate development of biomedical discoveries

Low and high exercise intensities differentially influence brain function, study shows

Research uncovers how HIV develops resistance to key drugs

Potential new biomarker for vascular dementia identified

Sugary diet can promote periodontal diseases

WPI researcher awarded grant for research into leading cause of aortic valve dysfunction

Researchers use new technique to improve the ability to model lung diseases

New study lays foundation for next generation aortic grafts

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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