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Novel method for creating chemical reactions could unlock many new applications

Scientists have broken the rules of enzyme engineering to unlock a new method for creating chemical reactions that could unlock a wide range of new applications - from creating new drugs to food production.

2 Dec 2020

Researchers develop telomerase gene therapy for treating different pathologies

After several years of research and many joint scientific publications, molecular biologists Maria Blasco (National Cancer Research Centre, CNIO) and Fàtima Bosch (Universitat Autònoma de Barcelona, UAB) have developed a telomerase gene therapy for the treatment of different pathologies related to shortening telomeres and, therefore, ageing.

2 Dec 2020

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Immunotherapies have transformed the landscape of cancer treatment by allowing physicians to alter or augment patients' immune response to better attack malignant tumors.

2 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

Novel ALS study effectively visualizes neuroinflammation

A novel ALS (amyotrophic lateral sclerosis) study has pooled data from multiple sites to effectively visualize neuroinflammation, which is key to developing drugs to treat the disease.

2 Dec 2020

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

If there is a silver lining in cancer's chaotic biology, it's that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

2 Dec 2020

Researchers devise new molecular imaging strategy to observe the sperm selection process

A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way.

2 Dec 2020

New, improved probes could make it easier to validate rapid COVID-19 diagnostic tests

Nanoengineers at the University of California San Diego have developed new and improved probes, known as positive controls, that could make it easier to validate rapid, point-of-care diagnostic tests for COVID-19 across the globe.

2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Reducing the delay in neurofeedback can increase the efficacy of training

HSE University scientists have for the first time in the world investigated the impact of delayed reinforcement signals in neurofeedback (NFB) training.

2 Dec 2020

Previously uncharacterized protein regulates mitochondrial NAD transporter

For their growth, cells need various nutrients and vitamins. So-called solute carriers (SLC), proteins that can transport such substances across the boundaries of cellular membranes, play a central role in metabolism.

1 Dec 2020

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

A repurposed mouse model can develop symptoms of both severe COVID-19 (lung damage, blood clots, abnormal blood vessels, and death) and also of milder disease, including loss of the sense of smell, according to a recent University of Iowa study published in Nature.

1 Dec 2020

Medically active component of cannabis does not impact driving ability, study shows

A landmark study on how cannabis affects driving ability has shown that cannabidiol (CBD), a cannabis component now widely used for medical purposes, does not impair driving, while moderate amounts of the main intoxicating component tetrahydrocannabinol (THC) produce mild driving impairment lasting up to four hours.

1 Dec 2020

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

Nanomedicine's giant step into the fight against the COVID-19

A recent editorial in Nature Nanotechnology discusses the enormous feat of scientific innovation, with messenger RNA (mRNA)-based vaccines developed to deliver the gene sequence of specific SARS-CoV-2 viral proteins into host cells using nanotechnology platforms.

1 Dec 2020

Study may help to better understand the pathological process involved in brain diseases

A team of researchers at the Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer's disease and several other neurodegenerative disorders.

1 Dec 2020

Study uncovers a promising therapeutic target for retinal dystrophies

A team of LSU Health New Orleans researchers reports for the first time that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

1 Dec 2020

KU Leuven vaccine candidate works against yellow fever and SARS-CoV-2 infection

Virologists at the Rega Institute at KU Leuven (Belgium) have developed a vaccine candidate against Covid-19 based on the yellow fever vaccine, which as a result also works against yellow fever. Results published today in Nature show that the vaccine protects hamsters from infection with the SARS-CoV-2 coronavirus after a single dose.

1 Dec 2020

Experimental drug can reverse age-related memory decline in mice

Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists.

1 Dec 2020

2018 anthrax outbreak in Uganda tied to infected cow meat, study finds

On April 18, 2018, 7 suspected human anthrax cases were reported from the Kween District Health Office in Kween District, Uganda. Ugandan researchers from the Uganda Public Health Fellowship Program, Kampala, Uganda, have now published their findings on the outbreak's source in the latest issue of the CDC's (Centre for Disease Prevention and Control) Emerging Infectious Diseases.

1 Dec 2020

Medical Science News

Novel method for creating chemical reactions could unlock many new applications

Researchers develop telomerase gene therapy for treating different pathologies

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Novel ALS study effectively visualizes neuroinflammation

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

Researchers devise new molecular imaging strategy to observe the sperm selection process

New, improved probes could make it easier to validate rapid COVID-19 diagnostic tests

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

Reducing the delay in neurofeedback can increase the efficacy of training

Previously uncharacterized protein regulates mitochondrial NAD transporter

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

Medically active component of cannabis does not impact driving ability, study shows

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Nanomedicine's giant step into the fight against the COVID-19

Study may help to better understand the pathological process involved in brain diseases

Study uncovers a promising therapeutic target for retinal dystrophies

KU Leuven vaccine candidate works against yellow fever and SARS-CoV-2 infection

Experimental drug can reverse age-related memory decline in mice

2018 anthrax outbreak in Uganda tied to infected cow meat, study finds

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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