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Study: Plant-based diet boosts metabolism

A plant-based diet boosts after-meal burn, leads to weight loss, and improves cardiometabolic risk factors in overweight individuals, according to a new randomized control trial published in JAMA Network Open by researchers with the Physicians Committee for Responsible Medicine.

30 Nov 2020

Experimental vaccine protects cynomolgus macaques against Crimean-Congo hemorrhagic fever virus

An experimental vaccine developed in Europe to prevent infection by Crimean-Congo hemorrhagic fever virus (CCHFV) has protected cynomolgus macaques in a new collaborative study from National Institutes of Health scientists.

30 Nov 2020

Validated biomarkers can reveal individual’s risk of developing Alzheimer’s

A new study from Lund University in Sweden shows that validated biomarkers can reveal an individual's risk of developing Alzheimer's disease.

30 Nov 2020

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Laboratory research and analysis of epidemiological data by Silvia Corvera, MD, and Tiffany Moore Simas, MD, MPH, MEd, and colleagues show that low levels of a protein commonly seen in screening tests for chromosomal disorders during the first trimester of pregnancy is associated with adipose tissue remodeling, glucose resistance and gestational diabetes mellitus in pregnant women.

30 Nov 2020

Adding exercise to genetic treatment reverses fatigue in mice with common myotonic dystrophy

Adding exercise to a genetic treatment for myotonic dystrophy type 1 (DM1) was more effective at reversing fatigue than administering the treatment alone in a study using a mouse model of the disease.

30 Nov 2020

Machine learning model uses retinal scans to detect Alzheimer’s disease

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer's disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University.

30 Nov 2020

Penn study opens the door to let CAR T cells reach the tumor microenvironment

The labyrinth of jumbled blood vessels in the tumor microenvironment remains one of the toughest blockades for cellular therapies to penetrate and treat solid tumors.

30 Nov 2020

Mollusc-derived compounds potential medicines for COVID-19 and other respiratory diseases

A research team has reviewed the existing literature on compounds derived from molluscs used for treating respiratory diseases.

30 Nov 2020

Mexican case study finds similar mortality rates in diabetic patients with and without COVID-19

In a large case study based in Mexico, researchers recently examined the mortality risk associated with diabetes in symptomatic COVID-19 patients.

30 Nov 2020

What are the risks associated with human challenge trials for SARS-CoV-2 vaccine candidates?

Researchers from the University of Haifa, Israel, and WAW Statistical Consulting Ltd, UK, designed a model that helps determine the risks faced by participants in a hypothetical COVID-19 dosing study.

30 Nov 2020

Transmission 'hot zones' drive COVID-19 infection patterns, says study

A recent study describes two different mathematical models of high infection zones, which lead to different effects on viral transmission. This underlines the need to understand how the virus spreads within a community as well as within subgroups with different patterns of interaction.

30 Nov 2020

Scientists develop new tools to detect very early changes in Alzheimer’s disease

Researchers at the University of Gothenburg in Sweden, together with their colleagues at the Barcelona Beta Research Centre in Spain, the University Medical Centre in Ljubljana, Slovenia, and the University of Paris, have found new forms of tau protein that become abnormal in the very early stages of Alzheimer's disease before cognitive problems develop.

30 Nov 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Scientists develop novel biomaterial that accelerates bone healing

Scientists have developed a new biomaterial that helps bones heal faster by enhancing adults' stem cell regenerative ability.

30 Nov 2020

Severe COVID-19 can produce high long-term neutralizing antibodies, study finds

A new study published by a team of scientists in Spain indicates that neutralizing immunity can last for up to 8 months, despite a steep drop in antibody titer over this time.

30 Nov 2020

Are SARS-CoV-2 protease inhibitors effective antivirals in treating COVID-19?

Many antiviral development studies have focused on the possibility of inhibiting the main viral protease (Mpro), and papain-like protease (PLpro), given their central role in viral replication. A new study draws attention to the high odds that these may not have anti-infective activity because of the redundant pathways present in human host cells.

30 Nov 2020

UK’s post-lockdown COVID-19 restrictions allows families to celebrate Christmas 2020 together

The UK's three-tier system of COVID-19 restrictions could be tweaked to allow a more effective control of viral spread, while still ensuring that families can choose their own course of action over the Christmas holidays, says a new preprint published on the medRxiv* server in late November 2020.

30 Nov 2020

Excessive use of antibiotics during COVID-19 pandemic could intensify drug resistance

A new study published in the journal Science of The Total Environment in November 2020 discusses this potentially serious issue along with its wider consequences.

30 Nov 2020

Could the keto diet help prevent or mitigate severe COVID-19?

A new study published in the journal of Translational Medicine reports that the ketogenic diet (KD) may be useful in this area, with its track history of effectual reduction of fat mass, anti-inflammatory and immunomodulatory effects, and consequent improvement of cardiovascular health.

30 Nov 2020

Systemic inflammation increases over various stages of liver cirrhosis, shows study

Patients with liver cirrhosis display a wide range of clinical symptoms. A prospective study conducted by MedUni Vienna has now shown that blood levels of biomarkers for systemic inflammation increase over the various stages of the disease and can predict the development of complications, even in previously asymptomatic patients.

30 Nov 2020

Medical Science News

Study: Plant-based diet boosts metabolism

Experimental vaccine protects cynomolgus macaques against Crimean-Congo hemorrhagic fever virus

Validated biomarkers can reveal individual’s risk of developing Alzheimer’s

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Adding exercise to genetic treatment reverses fatigue in mice with common myotonic dystrophy

Machine learning model uses retinal scans to detect Alzheimer’s disease

Penn study opens the door to let CAR T cells reach the tumor microenvironment

Mollusc-derived compounds potential medicines for COVID-19 and other respiratory diseases

Mexican case study finds similar mortality rates in diabetic patients with and without COVID-19

What are the risks associated with human challenge trials for SARS-CoV-2 vaccine candidates?

Transmission 'hot zones' drive COVID-19 infection patterns, says study

Scientists develop new tools to detect very early changes in Alzheimer’s disease

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

Scientists develop novel biomaterial that accelerates bone healing

Severe COVID-19 can produce high long-term neutralizing antibodies, study finds

Are SARS-CoV-2 protease inhibitors effective antivirals in treating COVID-19?

UK’s post-lockdown COVID-19 restrictions allows families to celebrate Christmas 2020 together

Excessive use of antibiotics during COVID-19 pandemic could intensify drug resistance

Could the keto diet help prevent or mitigate severe COVID-19?

Systemic inflammation increases over various stages of liver cirrhosis, shows study

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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