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Biodegradable bridge for nerve injuries

Researchers have successfully tried a biodegradable bridge like device (biodegradable polycaprolactone PCL conduit) in vivo for management of nerve injuries. The team published their findings in a paper titled, “Long-gap peripheral nerve repair through sustained release of a neurotrophic factor in nonhuman primates,” in the latest issue of the journal Science Translational Medicine.

26 Jan 2020

Snake stem cells create real venom to use as medicine

Poisonous snakes kill more than 90,000 people each year across the globe, with about 1.2 million to 5.5 million snake bites occur annually. Despite the venomous bite, scientists have limited knowledge of the snake’s venom, complicating efforts to develop treatments. A new study has found that snake venom gland cells can be cultured in the lab as adult-stem-cell-based organoids, producing real venom, which can be used to develop treatments.

26 Jan 2020

Scientists build first-person view video database to provide visual data in line with human experience

To better understand the organization of the brain and the perceptual tendencies in humans, a team of four scientists are recording video from four head-mounted cameras - with eyetracking and head movement - and assembling a massive video database with more than 240 hours of first-person video that can be used by researchers everywhere.

25 Jan 2020

A microdose lithium formulation could halt signs of Alzheimer's pathology

There remains a controversy in scientific circles today regarding the value of lithium therapy in treating Alzheimer's disease.

24 Jan 2020

Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

A new study suggests that significant early childhood exposure to traffic-related air pollution (TRAP) is associated with structural changes in the brain at the age of 12.

24 Jan 2020

UMD entomologists recognized by AAAS with 2019 Newcomb Cleveland Prize

The American Association for the Advancement of Science awarded its 2019 Newcomb Cleveland Prize to University of Maryland entomologists Raymond St. Leger, Brian Lovett and their seven West African collaborators.

24 Jan 2020

UCI-led study reveals link between early life adversity and opioid addiction

Individuals with a history of early life adversity are disproportionately prone to opioid addiction. A new UCI-led study reveals why.

24 Jan 2020

The influence of neuroanatomy on treatment response of patients with trigeminal neuralgia

A new study published in the journal Cephalalgia, the official journal of the International Headache Society, shows unprecedented data regarding the neuroanatomical influence on the treatment response of patients with trigeminal neuralgia.

24 Jan 2020

Opioid dependence produces permanent changes in the brains of rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction.

24 Jan 2020

Researchers observe fast and slow molecular pathways that support memory function

A sustained state of vigilance will generate a different type of memory than a momentary startle, and these differences are linked to distinct signaling molecules in the brains of mice.

24 Jan 2020

Why yogurt consumption may help reduce breast cancer risk

One of the causes of breast cancer may be inflammation triggered by harmful bacteria say researchers.

24 Jan 2020

Findings highlight multisensory interactions in the human brain

Gravity is the unseen force that dominates our entire lives. It's what makes walking uphill so difficult and what makes parts of our body eventually point downhill. It is unyielding, everywhere, and a force that we battle with every time we make a move.

24 Jan 2020

RB1 alterations in cancer cells may lead to treatment resistance

The Cancer Genetics Group of the Josep Carreras Leukaemia Research Institute, led by Montse Sánchez-Céspedes, together with Luis Montuenga from CIMA, and Enriqueta Felip from Vall d'Hebron Hospital, has revealed that inactivation of RB1 through intragenic rearrangements is frequent in lung cancer cells from non-smoking patients with EGFR mutations.

24 Jan 2020

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing the gastrointestinal tract.

24 Jan 2020

3D capillary system offers a new approach to investigate obstruction of microvessels

Engineered human capillaries are providing an astounding view of how red blood cells transit ultra-small blood vessels.

23 Jan 2020

Researchers identify liver fibrosis ‘off switch’ in mice

Chronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue.

23 Jan 2020

Scientists discover small molecule that may slow or stop Parkinson's progression

A collaboration between scientists at Rutgers University and The Scripps Research Institute led to the discovery of a small molecule that may slow down or stop the progression of Parkinson's disease.

23 Jan 2020

Landmark study identifies 102 genes associated with autism risk

In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism. The study also shows significant progress towards teasing apart the genes associated with ASD from those associated with intellectual disability and developmental delay, conditions which often overlap.

23 Jan 2020

Scientists use human stem cells to make pain-killing neurons

Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment.

23 Jan 2020

Researchers identify novel cellular entry factor for AAV vector types

Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types--the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors-or vehicles--that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.

23 Jan 2020

Medical Science News

Biodegradable bridge for nerve injuries

Snake stem cells create real venom to use as medicine

Scientists build first-person view video database to provide visual data in line with human experience

A microdose lithium formulation could halt signs of Alzheimer's pathology

Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

UMD entomologists recognized by AAAS with 2019 Newcomb Cleveland Prize

UCI-led study reveals link between early life adversity and opioid addiction

The influence of neuroanatomy on treatment response of patients with trigeminal neuralgia

Opioid dependence produces permanent changes in the brains of rats

Researchers observe fast and slow molecular pathways that support memory function

Why yogurt consumption may help reduce breast cancer risk

Findings highlight multisensory interactions in the human brain

RB1 alterations in cancer cells may lead to treatment resistance

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

3D capillary system offers a new approach to investigate obstruction of microvessels

Researchers identify liver fibrosis ‘off switch’ in mice

Scientists discover small molecule that may slow or stop Parkinson's progression

Landmark study identifies 102 genes associated with autism risk

Scientists use human stem cells to make pain-killing neurons

Researchers identify novel cellular entry factor for AAV vector types

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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