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Researchers identify an immune cell that helps keep time in the gut

As people go through their daily and nightly routines, their digestive tracts follow a routine, too: digesting food and absorbing nutrients during waking hours, and replenishing worn-out cells during sleep. Shift work and jet lag can knock sleep schedules and digestive rhythms out of whack.

4 Oct 2019

Targeting HDAC2 reduces MDM2 expression and has anti-tumor effects in dedifferentiated liposarcoma

The cover for issue 55 of Oncotarget features Figure 3, "Romidepsin exhibits anti-tumor effect in xenograft model of DDLPS," by Seligson, et al.

4 Oct 2019

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

The cover for issue 54 of Oncotarget features Figure 2, "Comparative proteomic profiling of the peptides/proteins identified from 293T, IL16lamp2b and mExo-Tat samples," by Lu, et al.

4 Oct 2019

Researchers develop new way of 3D printing soft biomaterials

A new way of 3D printing soft materials such as gels and collagens offers a major step forward in the manufacture of artificial medical implants.

4 Oct 2019

Chinese activists criticize the use of traditional treatments, defend modern medical science

In the West, the number of people challenging scientific authority has been growing in past decades. This has, among other things, led to a decline in the support for mass vaccination programs and to an increase in alternative forms of treatment.

4 Oct 2019

Potential metabolism target could slow or prevent breast cancer metastasis

Cancer cells - especially the more aggressive ones - seem to have an ability to change. It's how they evade treatment and spread throughout the body.

4 Oct 2019

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

"Goldilocks" balance holds key to awakening the body's immune response to combat brain cancer

In the story of Goldilocks, a little girl tastes three different bowls of porridge to find which is not too hot, not too cold, but just the right temperature. In a study published in Advanced Therapeutics, University of Minnesota Medical School researchers report on a "Goldilocks" balance which holds the key to awakening the body's immune response to fight off brain cancer.

4 Oct 2019

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.

4 Oct 2019

New defensive mechanism against bacterial wound infections discovered

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité - Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria.

4 Oct 2019

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Multiple sclerosis, an autoimmune disorder, is known to be driven by "helper" T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study from Boston Children's Hospital pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them.

4 Oct 2019

Phage engineering gives antibacterial therapy a new lease of life

Researchers have been identifying and modifying known phages to fight against infectious bacteria.

4 Oct 2019

How mothers transfer the DNA inside their mitochondria to their babies

A recent study has revealed how DNA inside the cell's powerhouse comes from the mother's side.

4 Oct 2019

Scientists uncover the cause of a rare fatal nerve disease

A new study has revealed the cause of Pelizaeus-Merzbacher syndrome and how simply adding a chemical that binds to iron, so it can be removed from the cell, enables the sick cells to grow back.

4 Oct 2019

Even diet drinks increase the risk of type 2 diabetes, finds study

Drinking more than two artificially sweetened or sugary soft drinks each day may increase the risk of diabetes, say Harvard researchers.

4 Oct 2019

Low-magnetic field MRI produces clearer images and improves safety for patients with pacemakers

Researchers have developed a high-performance, low magnetic-field MRI system that produces superior images of the body’s internal structures and is also safer.

4 Oct 2019

Men should stay alcohol-free for at least six months before conception

A new study has revealed that men hoping to conceive should stop drinking for at least six months before to prevent congenital heart diseases.

4 Oct 2019

Study sheds new light on transmission dynamics of HIV-1B virus in Indonesia

Research into the molecular phylogeny (evolutionary history) of the HIV-1B virus in Indonesia has succeeded in illuminating the transmission period and routes for three clades (main branches of the virus).

4 Oct 2019

KIT researchers develop close-to-reality computer models of the heart

Digital simulations of human organs can be used to study the development of diseases and to customize therapies for patients.

4 Oct 2019

Researchers identify new targets to treat fibrotic diseases

When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term - but bad when myofibroblast activation gets out of hand.

4 Oct 2019

Medical Science News

Researchers identify an immune cell that helps keep time in the gut

Targeting HDAC2 reduces MDM2 expression and has anti-tumor effects in dedifferentiated liposarcoma

HIV-1 Tat expression leads to perturbations in cellular protein expression, research suggests

Researchers develop new way of 3D printing soft biomaterials

Chinese activists criticize the use of traditional treatments, defend modern medical science

Potential metabolism target could slow or prevent breast cancer metastasis

GW researchers show connection between bacteria in the microbiome and colon cancer

"Goldilocks" balance holds key to awakening the body's immune response to combat brain cancer

NUS researcher invents novel transfection technique to deliver DNA into immune cells

New defensive mechanism against bacterial wound infections discovered

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Phage engineering gives antibacterial therapy a new lease of life

How mothers transfer the DNA inside their mitochondria to their babies

Scientists uncover the cause of a rare fatal nerve disease

Even diet drinks increase the risk of type 2 diabetes, finds study

Low-magnetic field MRI produces clearer images and improves safety for patients with pacemakers

Men should stay alcohol-free for at least six months before conception

Study sheds new light on transmission dynamics of HIV-1B virus in Indonesia

KIT researchers develop close-to-reality computer models of the heart

Researchers identify new targets to treat fibrotic diseases

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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