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New grants support research on mechanics of tumor cells

At the cellular level, cancer can be viewed as a mechanical engineering challenge. The disease alters the structure and function of cells and tissues, which are meant to perform very specific tasks.

8 Oct 2019

Study reveals link between alterations in RNA splicing and Alzheimer's disease

A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer's disease.

8 Oct 2019

Using blood and plasma for earlier detection of Alzheimer's disease

The promise of earlier detection of diseases such as Alzheimer's is welcome news to the millions of families in the United States already affected by the various types of dementia. Emerging techniques such as spinal taps have shown success, but they are not effective for everyone.

8 Oct 2019

Maternal obesity accelerates rate of aging of metabolic problems in offspring

It has long been known that obesity impairs our metabolism and predisposes to diabetes and heart disease. New research in The Journal of Physiology has shown that the effects of maternal obesity even pass across generations to offspring, accelerating the rate of aging of metabolic problems that occur in normal life.

8 Oct 2019

Annual income drops linked to reduced brain health in middle age

Young adults who experience annual income drops of 25 percent or more may be more at risk of having thinking problems and reduced brain health in middle age, according to a study published online in Neurology, the medical journal of the American Academy of Neurology.

8 Oct 2019

Attention intimately linked to how people learn about danger, study shows

A new analysis of how people prioritize their attention when determining safety and danger in busy settings, such as crossing a road, suggests that a person will pay more attention to something if they learn it is associated with danger.

From PLOS ONE 8 Oct 2019

Patients' blood samples and biopsies reveal secrets of lung cancer spread

Early signs that a patient’s lung cancer may spread and become untreatable can be picked up in samples of their blood and tumor, according to a trio of papers published in Nature Medicine today (Monday).

8 Oct 2019

UVA researchers uncover key contributor to multiple sclerosis

Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the University of Virginia School of Medicine shows.

8 Oct 2019

Researchers identify proteins critical for spreading of breast cancer to bones

Once breast cancer spreads to bone, treatment becomes nearly impossible. Breast cancer cells can lie dormant in the bone, often undetectable and able to escape typical treatments.

7 Oct 2019

Blocking a protein in immune cells may help reduce risk of heart attack and stroke

Blocking the mineralocorticoid receptor (MR)- a protein that helps maintain normal levels of salt and water in the body- in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health.

7 Oct 2019

Study identifies a common denominator that triggers asthma in favorable environments

In recent decades, asthma has become a major public health problem. The exponential increase in asthma cases in industrialized countries over the past 50 years is due to major changes in our environment.

7 Oct 2019

New genome-wide association study shines light on genetic risk factors for gout

Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.

7 Oct 2019

Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

Dry skin, pain, and itching... Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients.

7 Oct 2019

Study identifies genetic marker which could personalize treatment for Crohn's disease

The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment.

7 Oct 2019

UCI researcher given NIH Director's New Innovator Award to study learning and memory

University of California, Irvine researcher Kevin Beier, PhD, assistant professor of physiology and biophysics in the School of Medicine, received a 2019 NIH Director's New Innovator Award to study learning and memory in an effort to discover new treatments for behavioral symptoms of chronic stress and depression.

7 Oct 2019