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New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

The role of adenosine in neurodegeneration and brain regeneration

The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment for amyotrophyic lateral sclerosis.

8 Dec 2019

New technique holds promise in cancer research and science studies

A new technique reported this week in Science overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.

8 Dec 2019

Innovative consortium will provide access to newest clinical trials and medical breakthroughs

New Jersey residents will have access to the newest clinical trials and medical breakthroughs as a result of an innovative consortium between Rutgers University, Princeton University and the New Jersey Institute of Technology.

8 Dec 2019

Nanosize container can slip inside cells and deliver medicines, gene therapies

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size - even hefty ones attached to the gene-editing tool called CRISPR.

6 Dec 2019

Research shows link between clock genes and vitamin A pathway in the brain of Monarch butterflies

Biologists at Texas A&M University are making strides in understanding biological clock function in several model organisms and translating these studies into broader implications for human health.

6 Dec 2019

Multiplexed C dots track different cancer targets to improve treatment

For more than a decade, researchers have used glowing nanoparticles called Cornell dots, or C dots, to illuminate cancer cells, target tumors and even induce cell death.

6 Dec 2019

Researchers identify a missed opportunity in the treatment of ER+ breast cancers

In the United States, apart from some forms of skin cancer, breast cancer is the most common cancer in women. It is also the most common cause of death from cancer among Hispanic women and the second most common among all other women, after lung cancer.

6 Dec 2019

Fetal heart rate could predict future heart health of babies

Changes in heart rate due to low oxygen conditions experienced by the fetus during pregnancy could predict the future heart health of babies, suggests research published today in The Journal of Physiology.

6 Dec 2019

Breakthrough research develops novel vaccine poised to cure peanut allergies

Peanut allergies could become a thing of the past as breakthrough research from the University of South Australia develops a radically novel vaccination that's poised to cure the potentially life threatening condition.

6 Dec 2019

Kanazawa University researchers describe genetic typing of Pseudomonas putida

Pseudomonas putida is a bacterium occuring in soil, aquatic environments and plants. Although the virulence of Pseudomonas p. -- the ability of the bacterium to infect its host and inflict a disease -- is considered to be low, infection in severely ill patients can be lethal. P. putida strains (also called isolates) have been found in hospitals, e.g. in urine, blood or wound discharge from patients, and such clinical isolates have been found to display resistance to drugs.

6 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

UAB bioprinter shows potential to accelerate tissue engineering

The dream of tissue engineering is a computer-controlled manufacturing of complex and functional human tissue for potential organ regeneration or replacement.

6 Dec 2019

Researchers confirm two new prognostic markers for triple negative breast cancer

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.

5 Dec 2019

New approach can improve the activity of CAR-T cells against blood and solid cancers

A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.

5 Dec 2019

Researchers draw an evolutionary link between pregnancy and cancer malignancy

A UConn School of Dental Medicine researcher used pregnancy to unlock a missing link between various species of mammals and cancer malignancy--fundamentally changing the way we look at cancer metastasis.

5 Dec 2019

Dead birds forecast unexpected impact of climate change

A new study published Wednesday in the journal Ecology Letters reports that its look at the physical data of thousands of dead American migratory birds collected off the busy streets of high-rise Chicago shows a surprising fact. Namely, the average size of birds of all sorts has been shrinking over the forty years since the collection began, while their wingspan has increased. The scientists say these changes are adaptations to climate change. Is this a taste of things to come – for humans as well as for birds?

5 Dec 2019

Proteins circulating in the blood could help predict people's age

The carnival worker who tries to guess your age relies on aspects of your appearance, such as your posture and whether any wrinkles emanate from the corners of your eyes and lips. If the carny's guess is more than a few years off, you win a stuffed koala.

5 Dec 2019

New study examines link between sugars and cardiovascular disease

The impact of sugars on heart health depends on the dose and type of sugar consumed, suggests a new study led by researchers at St. Michael's Hospital.

5 Dec 2019

$Nerve signaling pathway crucial to healing fractures, study shows$

Nerve signaling pathway crucial to healing fractures, study shows

Sticks and stones may break one's bones, but healing them requires the production of a protein signal that stimulates the generation, growth and spread of vital nerve cells, or neurons, throughout the injured area.

5 Dec 2019