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Novel approach to reach the most difficult-to-access physiological locations

A team led by Professor Sylvain Martel at the Polytechnique Montréal Nanorobotics Laboratory has developed a novel approach to tackling one of the biggest challenges of endovascular surgery: how to reach the most difficult-to-access physiological locations.

3 Dec 2019

Justinianic plague did not wipe out the Romans as history books tell us

A new study has revealed that it was not plague that killed half of the world’s population and thus proved to be the downfall of the Roman Empire as we know from history. The study was published this week in the latest issue of Proceedings of the National Academy of Sciences. The study involved scholars from different fields including history, archaeology and science. The study is titled, “The Justinianic Plague: An inconsequential pandemic?”

3 Dec 2019

New findings may help researchers leverage ERAP1 to fight cancer

In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.

3 Dec 2019

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

3 Dec 2019

Researchers identify mechanism for spread of HIV-1

New insight on how a type of cell facilitates the spread of HIV-1 has been published today in the open-access journal eLife.

3 Dec 2019

Failure in proteasome transportation system may cause neurodegenerative diseases

All neurodegenerative diseases have a common thread: the appearance of protein clumps in the brain such as amyloid-beta plaques in Alzheimer's disease and alpha synuclein aggregates in Parkinson's.

3 Dec 2019

Researchers create artificial tactile perception in monkeys through direct brain stimulation

Researchers from Duke University and HSE University have succeeded in creating artificial tactile perception in monkeys through direct brain stimulation.

3 Dec 2019

Isolated components of Saussurea have positive effect on bone tissue regeneration

Saussurea controversa is a perennial herbaceous plant that has been traditionally used by the people of the Far East, Siberia, Tibet, and Mongolia to treat liver, kidney, digestive tract, and locomotive diseases. Its dried leaves are sold in pharmacies because their decoction is widely used as a medicine against cold and bronchitis. To understand what substances this plant owes its medicinal properties to, a team of scientists from Siberian State Medical University and Tomsk Polytechnic University extracted individual components from the plant and determined their composition.

3 Dec 2019

Researchers discover regulatory map of the human EphB4 gene

Pierluigi Scalia and coworkers at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University in Philadelphia, and the affiliated Italian research organization ISOPROG, have announced the regulatory map of the human EphB4 gene.

3 Dec 2019

Spinal implants could one day restore the ability to stand, walk in patients with paralysis

When Vivian Mushahwar first applied to grad school, she wrote about her idea to fix paralysis by rewiring the spinal cord.

3 Dec 2019

Deep learning shows potential to improve chest X-ray interpretation

A sophisticated type of artificial intelligence can detect clinically meaningful chest X-ray findings as effectively as experienced radiologists, according to a study published in the journal Radiology.

3 Dec 2019

Roswell Park-led scientists identify new defense mechanism against prostate cancer

A research team led by a scientist at Roswell Park Comprehensive Cancer Center has identified the molecule LRIG1 as an important endogenous tumor suppressor in prostate cancer. Writing in the journal Nature Communications, the team documents their findings from preclinical studies showing that overexpression of the LRIG1 protein inhibits prostate cancer development, while reducing naturally occurring LRIG1 promotes prostate tumor development.

3 Dec 2019

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Doctors bring dead donor heart back to life in US first

A team has become the first in the US to reanimate the heart of a deceased donor and transplant it into a recipient.

3 Dec 2019

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Gene expression profiling and other analyses conducted by Rutgers Cancer Institute of New Jersey researchers and colleagues examining drug resistance to a common antibody therapy for non-Hodgkin lymphoma have identified calcium signaling as a novel and exploitable target in overcoming this treatment obstacle.

3 Dec 2019

Researchers identify new drug target for treating neurological disorders

Understanding how the brain processes sweet, bitter and umami tastes may one day help researchers design more effective drugs for neurological disorders.

3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

New computational method can help predict and design allosteric functions in proteins

Called the "second secret of life", allostery is one of the most fundamental processes of biology and has been a central focus among scientists across the life sciences spectrum, from fundamental biology to drug development.

3 Dec 2019

Discovery could offer insight into different risk of diseases in African Americans

The percentage of African ancestry in a person's genome determines the level that certain genes are expressed, called mRNA, according to a new Northwestern Medicine study.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

Medical Science News

Novel approach to reach the most difficult-to-access physiological locations

Justinianic plague did not wipe out the Romans as history books tell us

New findings may help researchers leverage ERAP1 to fight cancer

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Researchers identify mechanism for spread of HIV-1

Failure in proteasome transportation system may cause neurodegenerative diseases

Researchers create artificial tactile perception in monkeys through direct brain stimulation

Isolated components of Saussurea have positive effect on bone tissue regeneration

Researchers discover regulatory map of the human EphB4 gene

Spinal implants could one day restore the ability to stand, walk in patients with paralysis

Deep learning shows potential to improve chest X-ray interpretation

Roswell Park-led scientists identify new defense mechanism against prostate cancer

Inhibition of a protease could improve the treatment of IBD, study shows

Doctors bring dead donor heart back to life in US first

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Researchers identify new drug target for treating neurological disorders

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

New computational method can help predict and design allosteric functions in proteins

Discovery could offer insight into different risk of diseases in African Americans

Key component of immune response is activated by short RNAs, shows study

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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