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Health risks linked with cocktail of man-made chemicals are overlooked

The cocktail of man-made chemicals that we are exposed to daily is a health risk which current regulations and risk assessment overlook. This is the conclusion of the EU Horizon 2020 EDC-MixRisk project that is now being presented.

27 Mar 2019

Using connectomics to gain insight into epilepsy

Abnormalities in structural brain networks and how brain regions communicate may underlie a variety of disorders, including epilepsy, which is one focus of a two-part Special Issue on the Brain Connectome in Brain Connectivity, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

27 Mar 2019

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found.

27 Mar 2019

Study offers new insights for vaccine development to prevent RSV disease

In healthy adults, RSV, or respiratory syncytial virus, feels like the common cold with a runny nose, chest congestion and cough.

27 Mar 2019

Simple parameter can help surgeons in making decisions to treat aneurysms

Aneurysms form as abnormal bulges or balloonings over an artery, and, if ruptured, can lead to serious health complications or even death. Some aneurysms can exist for a long time without rupturing, and the surgery involved in treating aneurysms can be quite risky, so a parameter to help guide surgeons is needed.

27 Mar 2019

Researchers study how the auditory system achieves accurate speech recognition

For humans to achieve accurate speech recognition and communicate with one another, the auditory system must recognize distinct categories of sounds - such as words - from a continuous incoming stream of sounds.

27 Mar 2019

Research provides opportunities for biological control of insect-borne pathogens

Researchers from INRA, CIRAD, CEA, the University of Montpellier, and Chicago and Vanderbilt Universities in the United States have developed an innovative method for analyzing the genome of the Wolbachia bacterium.

27 Mar 2019

Study uncovers large-scale brain patterns and networks that control sleep

An international study headed by researchers from Aarhus University has for the first time uncovered the large-scale brain patterns and networks which control sleep, providing knowledge which in the future may help the large proportion of people who experience problems sleeping.

27 Mar 2019

Encapsulating human beta cells with immune-repelling protein restores glucose metabolism in diabetic mice

Encapsulating human stem-cell-derived beta cells in microcapsules made with a protein that repels key immune cells restored glucose metabolism in diabetic mice and protected the cells from immune system attack, preventing the buildup of inflammatory fibrotic tissue that has plagued previous trials of encapsulated beta cells.

27 Mar 2019

Researchers identify brain region that helps execute cooperative tasks

Researchers identify a part of the brain that helps execute cooperative tasks.

27 Mar 2019

Discovery could lead to new drugs for pain conditions

If a particular protein is missing during the fetal stage, no neurons develop that convey pain, temperature and itch, a study from Karolinska Institutet in Sweden published in the journal Cell Reports shows. The discovery can eventually lead to new drugs for pain conditions.

27 Mar 2019

New short-pulse ultrasound technique enhances drug delivery to brains of mice

Scientists currently use long-wave pulses of ultrasound to deliver drugs, which can cause side effects. These new findings from Imperial on shorter-wave pulses could have implications for how drugs are used to help patients of Alzheimer's and other neurological diseases.

26 Mar 2019

Scientists identify mechanism of impaired wound healing in diabetes

Researchers at Karolinska Institutet have identified a mechanism that can explain the impaired wound healing in diabetes which can lead to diabetic foot ulcers. The study is published in the scientific journal PNAS, Proceedings of the National Academy of Sciences.

26 Mar 2019

Researchers identify metabolic target to prevent or slow progression of heart failure

Researchers with The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have identified a metabolic process in the heart that, if treated, could someday prevent or slow the progression of heart failure.

26 Mar 2019

Damage to anxiety-associated brain region heightens monkeys’ defensive response

Damage to parts of the orbitofrontal cortex heightens monkeys’ defensive response to non-threatening stimuli, according to new research published in JNeurosci. The study proposes a critical role for subregions of this brain area in different anxiety disorders.

From Society for Neuroscience 26 Mar 2019

Researchers identify the missing link in post-exercise boost to brain function

A discovery about how exercise improves brain function could be harnessed for research into ageing, and boosting learning and memory.

26 Mar 2019

VCU researchers home in on microRNA processing for new cancer therapies

More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs.

26 Mar 2019

Causes of diabetes decline or disappear when ‘zombie cells’ are removed, shows study

Mayo Clinic researchers and their collaborators have shown that when senescent cells -- also known as "zombie cells" -- are removed from fat tissue in obese mice, severity of diabetes and a range of its causes or consequences decline or disappear. The findings appear in Aging Cell.

26 Mar 2019

BU researchers identify biomarker and possible new therapy for melanoma

Researchers have identified a biomarker and a possible new therapy for melanoma.

26 Mar 2019

Aspirin could be used to treat patients with severe tuberculosis infection

Research led by the Centenary Institute in Sydney has found a brand new target for treating drug-resistant tuberculosis; our scientists have uncovered that the tuberculosis bacterium hijacks platelets from the body's blood clotting system to weaken our immune systems.

26 Mar 2019