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Wakefulness and novel sleep index may predict success of spontaneous breathing trial

Critically ill patients are more likely to be successfully weaned from a mechanical ventilator, or breathing machine, if they have higher levels of wakefulness and both their right and left brains experience the same depth of sleep, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

1 Mar 2019

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these two factors regulate the immune response is not well-understood.

1 Mar 2019

New X-ray measurement approach could lead to a better way to calibrate CT scanners

A new measurement approach proposed by scientists at the National Institute of Standards and Technology could lead to a better way to calibrate computed tomography scanners, potentially streamlining patient treatment by improving communication among doctors.

1 Mar 2019

New tool uncovers molecular causes of different diseases

Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously.

1 Mar 2019

Johns Hopkins study sheds light on resistance to radiation treatment

A new Johns Hopkins study offers promise towards someday being able to non-invasively examine changes in cancerous tumors to determine whether they'll respond to radiation treatment, before treatment even begins.

1 Mar 2019

Researchers take important step towards developing artificial ovaries for cancer patients

An interdisciplinary team of researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg led by Prof. Aldo R. Boccaccini from the Chair of Materials Science (biomaterials) and Prof. Dr. Ralf Dittrich from the Department of Obstetrics and Gynaecology at Universitätsklinikum Erlangen have taken an important step towards developing artificial ovaries for patients suffering from cancer.

1 Mar 2019

Brain regions process concrete and abstract concepts differently

A new review explores the different areas of the brain that process the meaning of concrete and abstract concepts. The article is published ahead of print in the Journal of Neurophysiology.

1 Mar 2019

Translucent wonder material used on stadium roofs helps measure protein particles

Understanding how proteins clump together is essential in modern pharmaceuticals. When these tiny particles aggregate, they can alter the effectiveness of both vaccines and drugs, especially many of the new, popular formulations derived from monoclonal antibodies.

1 Mar 2019

Lipid-filled particle plays role in immune function and metabolism

Researchers have discovered that fat tissue releases a lipid-filled particle that has a role in immune function and metabolism. The study, in mice, was published online in the journal Science.

1 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Engineer to develop drug-filled hydrogel to repair the damaged heart

After a heart attack, the cells in the heart muscle cannot get enough nutrients and oxygen to survive, so they die. A structural support network in the heart's wall can help those cells regenerate, however, two enzymes that break down the network are naturally increased after a heart attack, leaving the heart in a fight for its life.

28 Feb 2019

New mobile skin bioprinting system to treat large wounds or burns

Imagine a day when a bioprinter filled with a patient's own cells can be wheeled right to the bedside to treat large wounds or burns by printing skin, layer by layer, to begin the healing process. That day is not far off.

28 Feb 2019

Protein content of tumors correlates with treatment response and survival in glioma patients

Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient.

28 Feb 2019

Research provides evidence for greater reliance on terrestrial bipedalism by human ancestors

The oldest distinguishing feature between humans and our ape cousins is our ability to walk on two legs - a trait known as bipedalism. Among mammals, only humans and our ancestors perform this atypical balancing act.

28 Feb 2019

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.

28 Feb 2019

Stress controllability mitigates the negative effects

In individuals, stress exposure in adolescence increases vulnerability and risk of developing psychopathologies in adulthood, such as drug addiction, mood, anxiety, addiction to gambling, attention deficit hyperactivity disorder, etc.

28 Feb 2019

Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.

28 Feb 2019

Lactose-free, reduced-carbohydrate milk does not improve outcomes in severely malnourished children

Treating hospitalized, severely malnourished children with a lactose-free, reduced-carbohydrate milk formula does not improve clinical outcomes, according to a study published February 26 in the open-access journal PLOS Medicine by Robert Bandsma of the Hospital for Sick Children in Toronto, Canada, James Berkley of the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya, and colleagues.

28 Feb 2019

Study elucidates mechanism behind development of steroid diabetes

Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout the body, how these adverse effects are caused and by which organ are not well understood.

28 Feb 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

Medical Science News

Wakefulness and novel sleep index may predict success of spontaneous breathing trial

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

New X-ray measurement approach could lead to a better way to calibrate CT scanners

New tool uncovers molecular causes of different diseases

Johns Hopkins study sheds light on resistance to radiation treatment

Researchers take important step towards developing artificial ovaries for cancer patients

Brain regions process concrete and abstract concepts differently

Translucent wonder material used on stadium roofs helps measure protein particles

Lipid-filled particle plays role in immune function and metabolism

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Engineer to develop drug-filled hydrogel to repair the damaged heart

New mobile skin bioprinting system to treat large wounds or burns

Protein content of tumors correlates with treatment response and survival in glioma patients

Research provides evidence for greater reliance on terrestrial bipedalism by human ancestors

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Stress controllability mitigates the negative effects

Researchers reveal promising biomarker for vascular disease relapse

Lactose-free, reduced-carbohydrate milk does not improve outcomes in severely malnourished children

Study elucidates mechanism behind development of steroid diabetes

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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