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Delivery of drugs within the brain can be improved by utilizing LAT1

According to a new study carried out at the University of Eastern Finland, the distribution of drug molecules within the brain can be improved by utilizing LAT1, which is expressed highly in the brain.

24 Sep 2019

Research: Protein complex represents a new metabolic target for liver cancer

Disrupting a metabolic pathway in the liver in a way that creates a more "cancer-like" metabolism actually reduces tumor formation in a mouse model of liver cancer.

24 Sep 2019

New report highlights latest advances in cell-based therapies

A new report highlights the latest advances in cell-based therapies for the treatment of disorders of the musculoskeletal system, such as arthritis and osteoporosis, and it identifies key unanswered questions that should be addressed through ongoing research.

24 Sep 2019

Dogs can suffer from same autoimmune encephalitis as humans, research reveals

Researchers from North Carolina State University have found that dogs can suffer from the same type of autoimmune encephalitis that people do. The finding could lead to better screening methods for diagnosis and possibly more effective treatments for canine encephalitis.

24 Sep 2019

New microcapsules provide safe and effective delivery of drugs, biomolecules

Cracking an egg to release its yolk requires applying external force (like being smacked against the edge of a bowl) to overcome the strength of the eggshell.

24 Sep 2019

Scientists to present new findings on gene therapy at Neuroscience 2019

Gene therapy shows promise as a way to treat and cure presently incurable neurological diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS).

24 Sep 2019

Newly synthesized anticancer compound can block cancer signaling mechanism

Of the various different functions that proteins perform in a cell, a crucial one is the recognition and transmission of certain "signals," collectively referred to as signal transduction.

24 Sep 2019

Heart disease was bigger issue for human ancestors than originally thought, study reveals

A new imaging study of the mummified arteries of people who lived thousands of years ago revealed that their arteries were more clogged than originally thought, according to a proof-of-concept study led by a researcher with The University of Texas Health Science Center at Houston.

23 Sep 2019

Perturbed genes regulating white blood cells related to ASD genetics and symptom severity

Researchers at University of California San Diego School of Medicine say they are getting closer to identifying the mechanisms of autism spectrum disorder (ASD) and biomarkers that can aid in early diagnosis and predictions of symptom severity.

23 Sep 2019

New finding could become glioblastoma’s Achilles heel

Glioblastoma is the most frequent and aggressive brain cancer due to its ability to escape the immune system. However, the way in which this tumor manages to induce this immune tolerance was not known in detail.

23 Sep 2019

Onion and garlic intake associated with reduced risk of breast cancer

Onions and garlic are key ingredients in sofrito, a condiment that's a staple of Puerto Rican cuisine. They may also be a recipe for reducing the risk of breast cancer.

23 Sep 2019

Gene regulators work together to raise individual's risk of schizophrenia

Researchers have discovered that gene expression regulators work together to raise an individual's risk of developing schizophrenia.

23 Sep 2019

New discovery may revolutionize treatment of drug-resistant epilepsy

Researchers at Carnegie Mellon University have discovered that the spreading of seizures through the brain can be suppressed depending on the amount of pressure within the brain, an important discovery that may revolutionize the treatment of drug-resistant epilepsy.

23 Sep 2019

Brain scans of newborn babies made available online to advance research

The Developing Human Connectome Project has published ground-breaking MR brain scans of over 500 newborn babies, which researchers from all over the world can download and use to study how the human brain develops.

23 Sep 2019

Ruthenium probes shed new light on cause of Alzheimer's disease

Rice University researchers have found a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease.

23 Sep 2019

Scientists discover how neural circuits play critical role in learning and memory

A University of California, Irvine-led team of scientists has discovered how newly identified neural circuits in the brain's hippocampal formation play a critical role in object-location learning and memory.

23 Sep 2019

Light-activated metal compound cuts off cancer cell's 'power source'

A space-age metal that formed part of the asteroid that destroyed the dinosaurs could provide a new method of treating cancer tumors selectively using light.

23 Sep 2019

Electric baseball cap may help to reverse male pattern balding

Researchers have developed an electric patch that stimulates hair growth to help reverse male balding. The patch has now been embedded in a baseball cap.

23 Sep 2019

Study sheds light on mechanisms behind correlated electrical activity in neurons

"Like a book in which the single pages are not all different but carry small portions of common text, or like a group of people who whistle a very similar tune": this is how our brain cells work, say scientists. It is the phenomenon of "co-relation", in which individual neurons do not always act as independent units in receiving and transmitting information but as a group of individuals with similar and simultaneous actions.

23 Sep 2019

New method to grow core-shell nanofibrous scaffolds for repair of meniscus tears

Damage to the meniscus is common, but there remains an unmet need for improved restorative therapies that can overcome poor healing in the avascular regions.

23 Sep 2019