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Mayo Clinic researchers identify gene that may predict pancreatic cancer risk in diabetic patients

Mayo Clinic researchers have identified a gene called "UCP-1" that may predict the development of pancreatic cancer in people with Type 2 diabetes. Their findings are published in Gastroenterology.

25 Feb 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Specific gene variation associated with ADHD could be tied to substance addiction

Some variations in the gene LPHN3 -associated with the attention deficit/hyperactivity disorder (ADHD) in kids and adults- could favor likelihood to smoke, consume alcohol, cannabis and other addictive substances, according to an article published in the journal Translational Psychiatry, from the Nature Publishing Group.

25 Feb 2019

Study findings can help develop new drugs for ischemia

Russian scientists investigated the role of opioid receptors in protecting the heart from coronary disease: the lack of its blood supply.

25 Feb 2019

Researchers discover origin of resistance to lung cancer

For treating cancer, drugs based on molecules known as tyrosine kinase inhibitors are sometimes used. One such tyrosine kinase inhibitor, called osimertinib, has been used to treat EGFR-mutated lung cancer with a certain degree of efficacy.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

Fat cells exhibit circadian rhythms affecting critical metabolic functions, study finds

Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds.

25 Feb 2019

Using CRISPR to regulate genes in the rat brain

Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. Described in eNeuro, this technique paves the way for researchers to probe genetic influences on brain health and disease in model organisms that more closely resemble human conditions.

From Society for Neuroscience 25 Feb 2019

Study emphasizes real-time eye contact as basis for effective social interaction

In contrast to studies of mice and rats, new research published in eNeuro investigating the effect of methylphenidate (Ritalin) on neuronal activity in monkeys has found no effect of the drug on the prefrontal cortex.

From Society for Neuroscience 25 Feb 2019

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Researchers at Binghamton University, State University of New York have uncovered the unique way in which a type of Gram-negative bacterium delivers the toxins that make us sick. Understanding this mechanism may help design better ways to block and eventually control those toxins.

25 Feb 2019

Neuron-derived estrogen key to making memories

Estrogen in the brain is important to keep neurons communicating and memories being made, scientists report.

25 Feb 2019

Regular dietary peanut consumption after immunotherapy may extend allergy treatment benefits

Regular dietary peanut consumption after completing oral immunotherapy or sublingual immunotherapy for peanut allergy may provide continued protection against accidental exposures to the allergen, according to a new study led by Edwin Kim, MD, who presented the findings at the annual American Academy of Allergy, Asthma and Immunology conference in San Francisco.

25 Feb 2019

Egg oral immunotherapy could be safe way of desensitizing children, youth with egg allergy

UNC School of Medicine researcher Edwin Kim, MD, MS, says the results of a multi-year observational study are encouraging for those suffering from egg allergies.

25 Feb 2019

Risk of tick bite potentially leading to red meat allergy is higher than expected

Until now it has been believed that in order for a tick to trigger an allergic immune response to alpha-gal in humans, the tick would need to have recently fed on the alpha-gal-rich blood of a mammal.

25 Feb 2019

Paying more attention to antibiotic dosing could improve clinical outcomes for CF patients

Children and young adults with cystic fibrosis (CF) whose lung infections were treated with suboptimal doses of antibiotics had fewer changes in lung microbial diversity during the IV treatment, and their microbial diversity levels were higher 30 days later, a multi-institutional study that includes Children's researchers shows.

23 Feb 2019

UMass Amherst scientist explores role of citrus peel in decreasing gut inflammation

University of Massachusetts Amherst Professor Hang Xiao, Clydesdale Scholar of Food Science, has received a $1.5 million grant from the National Institutes of Health to study how substances produced in the gut from citrus compounds are involved in decreasing inflammation in the colon.

23 Feb 2019

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide. They are used above all for the treatment of inflammatory reactions. However, in spite of their indisputable effectiveness and frequent use, we do not yet fully understand the underlying mechanisms of these drugs.

23 Feb 2019

Different sleep schedules among teens may have dissimilar effects on cognition and glucose levels

Many adolescent students sleep less than the recommended duration of 8-10 hours a night. It is unclear; however, whether short night sleep combined with an afternoon nap is as good as having the same amount of sleep continuously during the night without a nap.

23 Feb 2019

Mechanism behind how diabetes causes muscle loss revealed

Diabetes mellitus is associated with various health problems including decline in skeletal muscle mass. A research group led by Professor Wataru Ogawa at the Kobe University Graduate School of Medicine revealed that elevation of blood sugar levels leads to muscle atrophy and that two proteins, WWP1 and KLF15, play key roles in this phenomenon.

23 Feb 2019

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

The composition of the microbiome - the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs - makes a decisive contribution to human health or disease.

23 Feb 2019

Medical Science News

Mayo Clinic researchers identify gene that may predict pancreatic cancer risk in diabetic patients

Researchers discover new and rare skeletal disease

Specific gene variation associated with ADHD could be tied to substance addiction

Study findings can help develop new drugs for ischemia

Researchers discover origin of resistance to lung cancer

Scientists identify cause of devastating pediatric brain disorder

Fat cells exhibit circadian rhythms affecting critical metabolic functions, study finds

Using CRISPR to regulate genes in the rat brain

Study emphasizes real-time eye contact as basis for effective social interaction

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Neuron-derived estrogen key to making memories

Regular dietary peanut consumption after immunotherapy may extend allergy treatment benefits

Egg oral immunotherapy could be safe way of desensitizing children, youth with egg allergy

Risk of tick bite potentially leading to red meat allergy is higher than expected

Paying more attention to antibiotic dosing could improve clinical outcomes for CF patients

UMass Amherst scientist explores role of citrus peel in decreasing gut inflammation

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Different sleep schedules among teens may have dissimilar effects on cognition and glucose levels

Mechanism behind how diabetes causes muscle loss revealed

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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