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Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

In the largest genetic analysis of polycystic ovary syndrome (PCOS) performed to date, an international consortium, including researchers at the Icahn School of Medicine at Mount Sinai, conducted a whole genome association study to identify common genetic architecture for different diagnostic criteria used to define the syndrome.

24 Dec 2018

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

Glial cell maturation is severely impaired in patients with Huntington's disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials.

24 Dec 2018

Soyasapogenol B: A new drug delivery technology for therapeutics

Multi-Walled Carbon Nanotubes (MWCNTs) are characterized by walls formed by a one atom thick sheet of carbon.

24 Dec 2018

Enhancers can be predicted through ChIP-seq technology

In genetics, an enhancer is a short region of DNA that can be bound by proteins to increase the likelihood that transcription of a particular gene will occur.

23 Dec 2018

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Lysosomes are filled with more than 50 different hydrolytic enzymes, which are capable of digesting most cellular components.

23 Dec 2018

Statins reduce the formation of brown adipose tissue

A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess weight or diabetes.

21 Dec 2018

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

A team of investigators from the Massachusetts General Hospital Department of Radiology has developed a system using artificial intelligence to quickly diagnose and classify brain hemorrhages and to provide the basis of its decisions from relatively small image datasets.

21 Dec 2018

Bacterial resistance to last-resort antibiotic is spreading at alarming rate in Vietnam

Researchers have discovered that polymyxin E-resistant Escherichia coli is widely prevalent among people living in rural Vietnam.

21 Dec 2018

Study explores energetics and stride variability during gait transition in mammals

A dog's gait, according to the American Kennel Club, is "the pattern of footsteps at various rates of speed, each distinguished by a particular rhythm and footfall." When dogs trot, for example, the right front leg and the left hind leg move together. This is an intermediate gait, faster than walking but slower than running.

21 Dec 2018

Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

Could a change in diet be beneficial to people with autoimmune diseases such as lupus? A Yale-led team of researchers have revealed how a dietary intervention can help prevent the development of this autoimmune disease in susceptible mice.

21 Dec 2018

New bacteria-based drug delivery system could radically expand cancer treatment options

An interdisciplinary team of three Virginia Tech faculty members affiliated with the Macromolecules Innovation Institute has created a drug delivery system that could radically expand cancer treatment options.

21 Dec 2018

New approach to destroy HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus - it is their metabolic (or energy-producing) activity1 that enables the virus to multiply.

21 Dec 2018

Pittsburgh research team studies big brain data for complex brain disorders

The National Science Foundation BIGDATA program awarded $1,200,000 to a research team led by the University of Pittsburgh Swanson School of Engineering to study the big brain data for complex brain disorders and design new algorithms that address computational challenges in multi-site collaborative data mining.

21 Dec 2018

Medical Science News

Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Glial cell maturation is severely impaired in patients with Huntington's disease

Soyasapogenol B: A new drug delivery technology for therapeutics

Enhancers can be predicted through ChIP-seq technology

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Statins reduce the formation of brown adipose tissue

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

Bacterial resistance to last-resort antibiotic is spreading at alarming rate in Vietnam

Study explores energetics and stride variability during gait transition in mammals

Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

New bacteria-based drug delivery system could radically expand cancer treatment options

New approach to destroy HIV reservoirs

Pittsburgh research team studies big brain data for complex brain disorders

Researchers discover new changes occurring in the brain in early Alzheimer's disease

Study: Cholesterol uptake is decreased in GM3S-deficient cells

CHLA researcher reveals how leukemia burrows within the bone marrow

Calorie-labeling may change the way your brain responds to food

Researchers present mechanisms, cellular targets involved with effects of TGF-Beta 1 muscle

Micropores in fabricated tissues allow nutrient and oxygen diffusion into core

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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