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Successful testing of multi-organ "human-on-a-chip" could replace animals as test subjects

The replacement of animals as test subjects is one step closer to reality with the successful testing of multi-organ "human-on-a-chip" models to recapitulate the 28-day experiments typically used in animals to evaluate the systemic toxicity of drug and cosmetic compounds.

22 Feb 2019

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts of the body, resulting in symptoms that range from numbness and tingling in the arms and legs to blindness and paralysis.

22 Feb 2019

Vitamin D supplementation less effective in the presence of obesity, shows study

A new Journal of Bone and Mineral Research study confirms that vitamin D supplementation is less effective in the presence of obesity, and it uncovers a biological mechanism to explain this observation.

21 Feb 2019

News study reanalyzes the effects of noncaloric sweeteners on gut microbiota

There is currently not enough evidence related to the effects of noncaloric sweeteners on appetite, short‑term intake, and risk of suffering from cancer or diabetes, as shown by a study recently published in the scientific journal 'Advances in Nutrition'.

21 Feb 2019

Genetic defect linked to pediatric liver disease identified

Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to Biliary atresia, the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children.

21 Feb 2019

Thousands with chronic UTIs are not receiving the treatment they need

Many women may not be receiving the treatment they need because the gold-standard tests for UTIs fail to detect a significant proportion of bacteria.

21 Feb 2019

New sepsis test could save thousands of lives

Researchers have used a biosensor that can quickly identify biomarkers of sepsis and has the potential to save thousands of lives.

21 Feb 2019

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

The body's ability to adapt to changing conditions and shifting physiologic demands is essential to survival. To do so, each cell must be able to dispose of damaged or unnecessary proteins--a quality-control mechanism critical for cellular performance and for the health of the entire organism.

21 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

Scientists demonstrate key role of salt in allergic immune reactions

Salt apparently affects allergic immune reactions. A team working with Prof. Christina Zielinski at the Technical University of Munich has demonstrated in cell cultures that salt leads to the formation of Th2 cells.

21 Feb 2019

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Elizabeth Delacruz can't crawl or toddle around like most youngsters nearing their second birthday.

21 Feb 2019

New intracellular delivery system using gold nano-stars

Researchers from Russian Academy of Sciences developed a new method for star-shaped nanoparticles synthesis based on laser irradiation.

21 Feb 2019

Johns Hopkins study describes cells that may help speed bone repair

Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair.

21 Feb 2019

Researchers discover a new promising target to improve HIV vaccines

In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus's outer envelope where a lineage of antibodies are able to dock and neutralize the virus.

21 Feb 2019

Researchers discover DNA modification that enhances our ability to extinguish fear

Researchers at The University of Queensland have discovered a DNA modification that enhances our ability to extinguish fear.

21 Feb 2019

Anticipatory signals in eye movements can help measure attentive capacity, learning with greater precision

How can we tell what a person is thinking? Sometimes, it is enough to observe one's behavior, for example, how they respond to a stimulus in the environment.

21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Transplanting bone marrow of young mice into old mice prevents cognitive decline

A new study has found that transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities.

20 Feb 2019

Researchers uncover mechanisms that prevent tooth replacement in mice

Most reptiles and fish have multiple sets of teeth during their lifetime. However, most mammals, such as humans, have only one set of replacement teeth and some mammals, like mice, have only a single set with no replacement.

20 Feb 2019

Viruses in the intestinal tracts can lead to islet autoimmunity and Type 1 diabetes

Researchers at the Center for Infection and Immunity at the Columbia University Mailman School of Public Health and the University of New South Wales, Sydney, Australia, provide new evidence supporting an association between elevated levels of enteroviruses in the intestinal tracts of children and islet autoimmunity, a precursor to Type 1 diabetes.

20 Feb 2019

Medical Science News

Successful testing of multi-organ "human-on-a-chip" could replace animals as test subjects

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Vitamin D supplementation less effective in the presence of obesity, shows study

News study reanalyzes the effects of noncaloric sweeteners on gut microbiota

Genetic defect linked to pediatric liver disease identified

Thousands with chronic UTIs are not receiving the treatment they need

New sepsis test could save thousands of lives

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

Johns Hopkins scientists find new compound that may prevent reperfusion injury

Scientists demonstrate key role of salt in allergic immune reactions

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

New intracellular delivery system using gold nano-stars

Johns Hopkins study describes cells that may help speed bone repair

Researchers discover a new promising target to improve HIV vaccines

Researchers discover DNA modification that enhances our ability to extinguish fear

Anticipatory signals in eye movements can help measure attentive capacity, learning with greater precision

Why melanoma tumors in the brain may be worse?

Transplanting bone marrow of young mice into old mice prevents cognitive decline

Researchers uncover mechanisms that prevent tooth replacement in mice

Viruses in the intestinal tracts can lead to islet autoimmunity and Type 1 diabetes

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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