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Study sheds new light on left ventricular dysfunction in ischemic heart disease

Ischemic heart disease is a growing cause of heart failure owing to the increasing prevalence of diabetes, hypertension, and obesity.

17 Feb 2019

Columbia researchers unravel why some glioblastomas respond to immunotherapy

Columbia researchers have learned why some glioblastomas--the most common type of brain cancer--respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy drugs and lead to the development of more broadly effective treatments.

17 Feb 2019

Patented IU discovery to treat ARDS has been optioned to Theratome Bio

A patented Indiana University School of Medicine discovery that uses proteins, lipids and nucleic acids secreted by adult stem cells to treat Acute Respiratory Distress Syndrome, or ARDS, has been optioned to Theratome Bio, an Indianapolis-based life sciences company.

17 Feb 2019

Study finds genetic vulnerability to use of menthol cigarettes

A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive.

15 Feb 2019

New technique using patients' own modified cells could help treat Crohn's disease

A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.

15 Feb 2019

Blood clot discovery could lead to development of better treatments for blood diseases

Scientists have discovered new ways in which the body regulates blood clots, in a discovery which could one day lead to the development of better treatments that could help prevent and treat conditions including heart diseases, stroke and vascular dementia.

15 Feb 2019

Testosterone is not the only hormone needed for penis development

A new study has revealed that in addition to testosterone, the masculinization process involves a hormone called androsterone, which originates in other tissues.

15 Feb 2019

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led by Rainer Oberbauer and his colleagues Roman Reindl-Schwaighofer and Andreas Heinzel from the Division of Nephrology and Dialysis at MedUni Vienna.

15 Feb 2019

Celiac disease may be caused by gastrointestinal infection in childhood

A new study has found that a childhood stomach bug may be the cause of celiac disease later in life. The findings could pave the way for a vaccine to protect against the disease.

15 Feb 2019

Study: High intensity exercise may improve health by increasing gut microbiota diversity

Bacteria, often synonymous with infection and disease, may have an unfair reputation. Research indicates there are as many, if not more, bacterial cells in our bodies as human cells, meaning they play an important role in our physiology.

15 Feb 2019

UVA scientists find potential explanation for mysterious cell death in Alzheimer’s, Parkinson’s

Scientists at the University of Virginia School of Medicine have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer’s, Parkinson’s and other neurodegenerative diseases.

15 Feb 2019

Common herbicide found to increase the risk of Non-Hodgkin Lymphoma

A new study has shown that the herbicide glyphosphate, could increase the risk of Non-Hodgkin Lymphoma by 41 percent among those who are exposed.

15 Feb 2019

Scientists implicate hidden genes in the severity of autism symptoms

Scientists at the University of Colorado Anschutz Medical Campus have implicated a largely hidden part of the human genome in the severity of autism symptoms, a discovery that could lead to new insights into the disorder and eventually to clinical therapies for the condition.

15 Feb 2019

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at The University of Texas MD Anderson Cancer Center presented today at the American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

Suspicious spots on the lungs of children with rhabdomyosarcoma do not behave like metastases

Rhabdomyosarcoma is a malignant soft tissue tumor in the muscle tissue of children and adolescents. About 20 children are diagnosed with rhabdomyosarcoma per year in the Netherlands. "Metastases in these children are often found in the lungs," says professor Hans Merks of the Princess Máxima Center for Pediatric Oncology, who led the study.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

Brain synchronization depends on the language of communication

Experts from the Basque research center BCBL have shown for the first time that the way in which the activity of two brains is connected depends on whether the dialogue takes place in the native language or in a foreign language.

15 Feb 2019