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Computational biological models help uncover wealth of knowledge about atherosclerosis

Researchers have identified a new gene-activation pathway caused by lipids associated with coronary artery disease, a finding that could help identify new directions in research and drug development. The study was published in June in Nature Communications.

29 Jun 2018

Modified natural killer cells may be new player in CAR-T immunotherapies

Emerging CAR-T immunotherapies leverage modified versions of patient's T-cells to target and kill cancer cells.

29 Jun 2018

Review discusses complexity of immune-suppressive mechanisms in tumor milieu of cancers

Cancers control immune systems and evade immune detection using mediators consisting of immune checkpoint molecules and cellular systems associated with immune suppression.

29 Jun 2018

Researchers discover how behavior is organized in the brain

Driving to work, typing an email or playing a round of golf--people perform actions such as these throughout the day.

29 Jun 2018

Scientists provide clear picture of mysterious component of the inner ear

A few years ago, Ian Swinburne, HMS research fellow in systems biology, noticed something odd while conducting a time-lapse microscopy study of the inner ear of zebrafish. A tiny structure in the inner ear was pulsing like clockwork, inflating and deflating over and over.

29 Jun 2018

New mouse model could shed light on autism subtype

Researchers at the UC Davis MIND Institute have created a mouse model for maternal antibody- related (MAR) autism spectrum disorder that closely mimics the physiology and behaviors seen in people with this form of ASD.

29 Jun 2018

Mount Sinai study could help doctors to better understand and manage diseases affecting the larynx

In a first-of-its-kind study, Mount Sinai researchers have used sensory mapping to discover that the posterior part of the larynx (closest to the swallowing tract) is the main area of the voice box to protect the airway from potentially dangerous swallowed or inhaled substances.

29 Jun 2018

Sound and object motion can help change perceptions about body size

Sound and object motion can be used to change perceptions about body size, according to a new study by an international team led by a researcher from the Universidad Carlos III de Madrid.

29 Jun 2018

Penn cancer researchers reveal secrets of 'hot' and 'cold' pancreatic tumors

So-called "hot" tumors filled with T cells are often considered to be more sensitive to immunotherapy compared to "cold" tumors with fewer T cells, but a clear demonstration of why has eluded cancer biologists--until now.

29 Jun 2018

Study focuses on sexual habits of fungus that causes athlete's foot

The sexual habits of Trichophyton rubrum, the fungus that causes athlete's foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and international collaborators in the journal Genetics.

29 Jun 2018

Adolescent drinking linked to changes in metabolite profile

Adolescent drinking is associated with changes in the metabolite profile, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

29 Jun 2018

Scientists pinpoint new mechanism to explain progression of Alzheimer's disease

Scientists have pinpointed minute exosomes as the main vehicle that allow the spread of toxic proteins that trigger the onset of Alzheimer's Disease across a person's brain network.

29 Jun 2018

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Researchers at Indiana University have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer's disease.

29 Jun 2018

Hearing partially restored in deaf lab mice using novel therapy

A small molecule of a drug has been successfully used to treat an inherited form of hearing loss in laboratory mice.

28 Jun 2018

Researchers reveal complexity of NMDA receptor drug discovery target

Know your target. Especially if your target is coming into focus for treating diseases such as schizophrenia and treatment-resistant depression.

28 Jun 2018

People with co-existing HCV and AUD experience greater psychiatric, immune problems

Infection with the hepatitis C virus is a contagious liver disease with symptoms that range from mild illness for a few weeks to serious, lifelong liver problems.

28 Jun 2018

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

A DNA-level biomarker (MGMT promoter methylation) can be used to help predict survival outcomes in patients with high-risk, low-grade gliomas, according to a new study conducted through the NRG Oncology/RTOG collaborative clinical trials group and led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

28 Jun 2018

A small molecule can inhibit chemotherapy resistance of certain tumors

A team of researchers from the CNRS and Université Nice Sophia Antipolis has just shown that a small molecule called methiothepin can inhibit the chemotherapy resistance of certain tumors.

28 Jun 2018

Human Vaccines Project and Seqirus collaborate to accelerate universal flu vaccine research

The Human Vaccines Project, a nonprofit public-private partnership focused on decoding the immune system to improve human health, and Seqirus, a global leader in the prevention of influenza, announced today that Seqirus is joining the Project's Universal Influenza Vaccine Initiative.

28 Jun 2018

Researchers show how mutant CALR protein triggers cancer

Researchers at Juntendo University report in the journal Leukemia how mutants of the protein calreticulin lead to molecular mechanisms triggering myeloproliferative neoplasms, which can cause cancer. The findings may lead to the development of novel therapies for certain types of blood cancer.

28 Jun 2018

Medical Science News

Computational biological models help uncover wealth of knowledge about atherosclerosis

Modified natural killer cells may be new player in CAR-T immunotherapies

Review discusses complexity of immune-suppressive mechanisms in tumor milieu of cancers

Researchers discover how behavior is organized in the brain

Scientists provide clear picture of mysterious component of the inner ear

New mouse model could shed light on autism subtype

Mount Sinai study could help doctors to better understand and manage diseases affecting the larynx

Sound and object motion can help change perceptions about body size

Penn cancer researchers reveal secrets of 'hot' and 'cold' pancreatic tumors

Study focuses on sexual habits of fungus that causes athlete's foot

Adolescent drinking linked to changes in metabolite profile

Scientists pinpoint new mechanism to explain progression of Alzheimer's disease

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Hearing partially restored in deaf lab mice using novel therapy

Researchers reveal complexity of NMDA receptor drug discovery target

People with co-existing HCV and AUD experience greater psychiatric, immune problems

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

A small molecule can inhibit chemotherapy resistance of certain tumors

Human Vaccines Project and Seqirus collaborate to accelerate universal flu vaccine research

Researchers show how mutant CALR protein triggers cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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