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Researchers develop new approach for studying Cryptosporidium in healthy human tissues

Washington State University researchers have developed a new approach for studying Cryptosporidium, a waterborne gastrointestinal parasite now recognized as one of the leading causes of potentially life-threatening diarrheal disease in young children worldwide.

26 Jun 2018

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.

26 Jun 2018

Researchers examine new influenza drug's mode of action in detail

The new influenza drug Xofluza, developed by the Japanese pharmaceutical company Shionogi, was approved for clinical use in Japan in February 2018.

26 Jun 2018

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Wearable defibrillators may be a safe and effective alternative to surgically implanted devices among children with ventricular arrythmias that increase the risk of sudden cardiac death, according to a new study.

26 Jun 2018

Learning from nature's design of mosquito to create painless microneedles

A mosquito can insert a needle-like probe into your skin and draw blood for several minutes without you even noticing.

26 Jun 2018

Serotonin enhances speed of learning, study finds

An international team from the Champalimaud Centre for the Unknown, in Portugal, and the University College London, in the UK, has uncovered a previously unknown effect of serotonin on learning.

26 Jun 2018

Experts witness action of influenza infection in the lungs of living mice

In the 1966 novel, Fantastic Voyage, written by biochemist and author Isaac Asimov, a crew of people become miniaturized in order to travel through the body of a scientist and save him from a blood clot in his brain.

26 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

Microbiologists and plant scientists pinpoint genetic weakness in cholera pandemic's armor

While cholera rages across many regions of the world, a team of microbiologists and plant scientists has pinpointed a genetic weakness in the pandemic's armor, which could lead to future treatments.

26 Jun 2018

Researchers explore how hypertension impairs cognitive function

The squeeze high blood pressure puts on fragile blood vessels in the brain appears to disrupt a normal, protective process that balances the blood flowing to our brains with the activity of our resting neurons.

26 Jun 2018

UVA research shows true nature of immune cells blamed in Alzheimer's

Immune cells commonly blamed in Alzheimer's and other neurodegenerative diseases are actually precision cleaning machines protecting the central nervous system, new research from the University of Virginia School of Medicine shows.

26 Jun 2018

Researchers identify novel mutation in amyloid diseases

Researchers have identified a one-of-a kind mutation in the DNA of a patient who died of transthyretin (TTR) amyloidosis, a progressive condition characterized by the buildup of abnormal deposits of a misfolded protein called amyloid in the body's organs and tissues.

26 Jun 2018

Scientists discover and characterize new toxin in cholera bacteria

The bacterium Vibrio cholerae was discovered more than 150 years ago but remains as one of the main causes of bacterial infectious disease globally, especially in low-income nations where it occurs endemic, and outbreaks of cholera disease can lead to major epidemics.

26 Jun 2018

Study suggests new approach for treating alcohol use disorder

Activation of a receptor with no known function in the brain reduces excessive alcohol use and the pain of withdrawal, according to preclinical research in male rats. The study, published in eNeuro, suggests a new approach towards the treatment of alcohol use disorder.

26 Jun 2018

Targeting proteins in semen could prevent sexually transmitted spread of Ebola virus

Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences.

26 Jun 2018

Study reveals new way to inhibit capillary leakage in sepsis

Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited by targeting vascular integrins.

25 Jun 2018

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.

25 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research.

25 Jun 2018

Medical Science News

Researchers develop new approach for studying Cryptosporidium in healthy human tissues

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

Researchers examine new influenza drug's mode of action in detail

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Learning from nature's design of mosquito to create painless microneedles

Serotonin enhances speed of learning, study finds

Experts witness action of influenza infection in the lungs of living mice

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

Microbiologists and plant scientists pinpoint genetic weakness in cholera pandemic's armor

Researchers explore how hypertension impairs cognitive function

UVA research shows true nature of immune cells blamed in Alzheimer's

Researchers identify novel mutation in amyloid diseases

Scientists discover and characterize new toxin in cholera bacteria

Study suggests new approach for treating alcohol use disorder

Targeting proteins in semen could prevent sexually transmitted spread of Ebola virus

Study reveals new way to inhibit capillary leakage in sepsis

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

Researchers discover immune profile for effective cancer immunotherapy

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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