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MD Anderson research provides insight into memory T cell development and disease relapse

Just like people, some T cells have excellent memories. These subtypes known as memory T cells may explain why some immunotherapies are more effective than others and potentially lead to researchers designing more effective studies using combination checkpoint blockade treatments, according to experts at The University of Texas MD Anderson Cancer Center.

16 Apr 2018

Research sheds light on links between brain growth and post-natal sensory experiences

New research by University of Toronto neuroscientists sheds light on links between early brain growth and sensations experienced by animals soon after birth.

16 Apr 2018

Precancerous colon polyps in Lynch syndrome patients display immune activation

Colon polyps from patients with Lynch syndrome, a hereditary condition that raises colorectal cancer risk, display immune system activation well before cancer development, according to research from The University of Texas MD Anderson Cancer Center.

16 Apr 2018

Early life stress impacts how the sensory systems develop, review shows

Life needs stimulation. However, overstimulation can cause exhaustion and illness. During specific sensitive periods early in life, stress can even affect later mental health.

16 Apr 2018

Engineered immune cells clear deadly pediatric brain tumor in mice

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

16 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Study shows connection between early life stress, depression and sleep disturbances

Early life stress, sleep disturbances and alterations in neuronal plasticity have been associated with depression, yet the relation between these factors and depression remain poorly understood.

16 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

Finding ways to reverse obesity’s lingering, pro-cancer effects

Like exposure to too much sun and drinking alcohol, obesity is a risk factor for cancer. Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center are working to be a part of the solution -- they want to find ways to reverse obesity-linked biological changes in the body that are associated with cancer growth.

16 Apr 2018

The memory area of the brain may also yield vital clues about mental health illnesses

The hippocampus is an area of the brain commonly linked with memory and dementia. But new U of T Scarborough research finds that it may also yield important clues about a range of mental health illnesses including addiction, anxiety and depression.

16 Apr 2018

Sleep deprivation increases brain protein linked to Alzheimer's disease

Losing just one night of sleep led to an immediate increase in beta-amyloid, a protein in the brain associated with Alzheimer's disease, according to a small, new study by researchers at the National Institutes of Health. In Alzheimer's disease, beta-amyloid proteins clump together to form amyloid plaques, a hallmark of the disease.

13 Apr 2018

Receptor that detects heat of red chili pepper may help protect the brain after TBI

A receptor on our immune cells that can detect both the heat of a red chili pepper and the extreme physical heat of a pizza oven may help protect the brain following a traumatic brain injury, scientists say.

13 Apr 2018

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

To get the extra energy they need to fuel their uncontrolled growth, cancer cells break down some of their own parts for fuel - a process known as autophagy, or "self-eating."

13 Apr 2018

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.

13 Apr 2018

Protein linked with Alzheimer's disease affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies.

13 Apr 2018

Scientists from Cure First and SEngine Precision Medicine discover common link in 28% of all cancers

Seattle scientists from Cure First, a non-profit research organization, and SEngine Precision Medicine, a biotech developing targeted, more effective, and less toxic cancer therapeutics, co-authored one of 27 high-profile papers published today by Cell Press.

13 Apr 2018

Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

Tweezers made of laser beams manipulate atoms to make new molecules

Researchers have devised optical tweezers made up of laser beams that could be used to manipulate and move tiny atoms to align them to form single molecules. This is a breakthrough and has been done for the first time by scientists from Harvard University. The work report was published in a study in the latest issue of the journal Science.

13 Apr 2018

Reducing sedentary behavior may be possible target to improve brain health

Sitting too much is linked to changes in a section of the brain that is critical for memory, according to a preliminary study by UCLA researchers of middle-aged and older adults.

12 Apr 2018

Researchers developing affordable, compact white blood cell counter

A thin copper wire wrapped around a channel slightly thicker than a strand of hair could be the key to manufacturing a compact electronic device capable of counting white blood cells from the comfort of one's home, a Kennesaw State University researcher says.

12 Apr 2018

Medical Science News

MD Anderson research provides insight into memory T cell development and disease relapse

Research sheds light on links between brain growth and post-natal sensory experiences

Precancerous colon polyps in Lynch syndrome patients display immune activation

Early life stress impacts how the sensory systems develop, review shows

Engineered immune cells clear deadly pediatric brain tumor in mice

Novel disease model for ALS and MS can be used to develop new immunotherapies

Study shows connection between early life stress, depression and sleep disturbances

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Finding ways to reverse obesity’s lingering, pro-cancer effects

The memory area of the brain may also yield vital clues about mental health illnesses

Sleep deprivation increases brain protein linked to Alzheimer's disease

Receptor that detects heat of red chili pepper may help protect the brain after TBI

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Protein linked with Alzheimer's disease affects different brain cells differently

Scientists from Cure First and SEngine Precision Medicine discover common link in 28% of all cancers

Research reveals immune suppressive role of soluble antibodies in tumor progression

Tweezers made of laser beams manipulate atoms to make new molecules

Reducing sedentary behavior may be possible target to improve brain health

Researchers developing affordable, compact white blood cell counter

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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