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ALS and frontotemporal dementia share genetic connections

Nearly half of all patients with amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder, develop cognitive problems that affect memory and thinking.

9 Apr 2018

Popular e-cigarette flavors produce different levels of toxins

The flavor of an e-cigarette may affect more than a consumer's taste buds, according to Penn State researchers who say the chemicals that make up different flavors also produce different levels of free radicals, toxins often associated with cancer and other diseases.

9 Apr 2018

Hypercaloric food intake promotes major behavioral and cognitive changes

Mice fed on a high fat or chocolate-based diet show abnormal feeding behaviors such as snacking, bingeing and disrupted eating patterns, according to new research from scientists at the Centre for Genomic Regulation and the Pompeu Fabra University in Barcelona, Spain.

9 Apr 2018

Patient's mucus may help predict type of chronic sinusitis

By April, nearly one-third of the U.S. is already experiencing high pollen levels while the weather and temperatures continue to fluctuate, aggravating sinus symptoms. A patient's mucus may predict the type of his or her chronic sinusitis, which could help doctors determine whether surgery or medical treatments can produce the best outcomes, according to a recently published Vanderbilt study.

9 Apr 2018

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using human brain cells, scientists at the Gladstone Institutes discovered the cause of--and a potential solution for--the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.

9 Apr 2018

Researchers develop new animal model to study Crimean-Congo hemorrhagic fever

Crimean-Congo hemorrhagic fever is a viral disease spread by ticks in the Middle East, Asia, Africa and parts of Europe. Infection with CCHF virus is fatal in nearly one of every three cases.

9 Apr 2018

Experts explore how degenerative processes impair the body's detoxification system

A poor diet and other risk factors can result in liver disease. This important metabolic organ can become fatty and inflamed. In the long term, this may result in irreversible and life-threatening organ damage (cirrhosis of the liver or 'shrunken liver').

9 Apr 2018

Oxidative stress due to lack of tumor suppressor gene promotes cancer progression, study shows

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified that RUNX3, a tumour suppressor gene absent in many cancer types, acts as a barrier against oxidative stress in cancer cells.

9 Apr 2018

Using Cord Blood to Alleviate the Symptoms of Autism

Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Dr. Ann Smith, director of Smart Cells who provided the cord blood for the trial, discusses the research and it's potential.

9 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Nosopharm, a company dedicated to the research and development of new anti-infective drugs, and the University of Illinois at Chicago today announce the publication of a study in Molecular Cell on the mechanism of action of odilorhabdins, a new class of antibiotics to combat antibiotic resistance.

9 Apr 2018

Bacteria that make high energy tiny carbon rings

Scientists have now bred bacteria that can create microscopic high energy carbon rings. This scientific breakthrough comes from Caltech scientists who have tweaked the enzymes of these bacteria in ways so that they can provide new molecular structures.

9 Apr 2018

Unexpected finding may play major role in deterring diabetic retinopathy

Diabetic retinopathy is considered one of the most disabling complications of diabetes and the leading cause of new cases of vision loss among adults.

6 Apr 2018

Research team identifies new class of antibiotics to fight drug resistance

Researchers from the University of Illinois at Chicago and Nosopharm, a biotechnology company based in Lyon, France, are part of an international team reporting on the discovery of a new class of antibiotics.

6 Apr 2018

New research could pave way for better influenza vaccines

Influenza vaccines that better target the influenza surface protein called neuraminidase (NA) could offer broad protection against various influenza virus strains and lessen the severity of illness, according to new research published in Cell.

6 Apr 2018

Penn research provides unprecedented insight into kidney physiology and disease

The kidney is a highly complex organ – far beyond a simple filter. Its function requires intricate interactions between many highly specialized cell types to extract waste, balances body fluids, form urine, regulate blood pressure, and secrete hormones.

6 Apr 2018

Mice study reveals important role of pTreg cell population in autoimmune diabetes

In autoimmune diseases such as type 1 diabetes, some of the immune system's T cells mistakenly attack the body's own cells, while protective T regulatory cells try to defend against that attack.

6 Apr 2018

Researchers discover Tfh cell dysfunction in HIV-infected patients

A team of chemical and biomedical engineers from the Cockrell School of Engineering at The University of Texas at Austin, in collaboration with researchers from the University of Pennsylvania, have discovered that HIV-infected patients experience a dysfunction in a certain type of immune cell: the follicular helper T (Tfh) cell.

6 Apr 2018

Scientists develop indices that provide information about prognosis of cancers

Researchers from the School of Medicine in Ribeirão Preto, at the University of São Paulo, in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy to be used and identify potential targets for the development of new drugs.

6 Apr 2018

Research provides new insights about gender differences in airway disease risk

Human airways already demonstrate gender-based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.

6 Apr 2018