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Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Heart failure after a heart attack is a global epidemic leading to chronic heart failure pathology. About 6 million people in the United States and 23 million worldwide suffer from this end-stage disease.

15 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

Researchers discover new way to target cancer without destroying healthy T-cells

A unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and difficult-to-treat family of cancers, finds a study involving researchers from Cardiff University.

15 Nov 2017

Researchers test new vaccination strategy against HIV-related SIV in monkeys

According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year.

15 Nov 2017

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

A team of Massachusetts General Hospital researchers has developed a potential alternative to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging.

15 Nov 2017

Researchers find that tiny brain region plays key role in social memory formation

Research by a group of scientists at the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore have discovered that a tiny brain region plays a critical role in the formation of social memory and interaction.

15 Nov 2017

Nanowires could be potential drug delivery tools for neurodegenerative diseases

Millions of Americans suffer from neurodegenerative diseases such as Alzheimer's and Parkinson's. Researchers have identified promising new treatments, such as cerebrolysin, but current clinical approaches are ineffective because critical concentrations of the drug dissipate within the body before reaching the blood-brain barrier and central nervous system.

15 Nov 2017

Eating nuts on a regular basis strengthens brainwave frequencies, study finds

A new study by researchers at Loma Linda University Health has found that eating nuts on a regular basis strengthens brainwave frequencies associated with cognition, healing, learning, memory and other key brain functions.

15 Nov 2017

Changes in multiple different genes drive world's most deadly forms of lung cancer

A new UC San Francisco–led study challenges the dogma in oncology that most cancers are caused by one dominant "driver" mutation that can be treated in isolation with a single targeted drug. Instead, the new research finds one of the world's most deadly forms of lung cancer is driven by changes in multiple different genes, which appear to work together to drive cancer progression and to allow tumors to evade targeted therapy.

15 Nov 2017

WFIRM-led project aims to study health risks astronauts face from exposure to space radiation

The Wake Forest Institute for Regenerative Medicine has been selected by NASA to lead a multi-institutional project to better understand the health risks astronauts face from the exposure to galactic cosmic ray (GCR) and solar energetic particle (SEP) radiation that occurs from long-duration missions in deep space, and to develop countermeasures to keep astronauts safe.

14 Nov 2017

UCR-led research discovers that human protein could be used to treat sepsis

A research team led by a biomedical scientist at the University of California, Riverside has discovered that the human protein resistin could be used to treat sepsis, the body's extreme and uncontrolled immune response to an infection.

14 Nov 2017

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Researchers from MIT have now developed nanoparticles that could carry CRISPR genetic editing systems deep within the cells and perform their functions on the DNA. The paper was published in the November issue of Nature Biotechnology.

14 Nov 2017

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs.

14 Nov 2017

Study provides new insights into basis for responsiveness of testicular cancer to chemotherapy

Cornell researchers have taken a major step toward answering a key question in cancer research: Why is testicular cancer so responsive to chemotherapy, even after it metastasizes?

14 Nov 2017

Chronic preconception exposure to genistein may adversely affect female fertility, mice study finds

Exposure to the phytoestrogen genistein prior to conception may adversely affect female fertility and pregnancy outcomes, depending on the dosage and duration of exposure, a new study in mice suggests.

14 Nov 2017

Breakthrough discovery could radically change approach to treating Klebsiella infections

Researchers at Queen's University Belfast together with the University of Vienna have discovered that treatment for the antibiotic-resistant bacteria Klebsiella pneumoniae could lie within our bodies' natural defenses.

14 Nov 2017

Research shows how food poisoning bacteria can multiply and spread inside micro-organisms

New research by a team from London's Kingston University has shown how the food poisoning bacteria Campylobacter can multiply and spread inside micro-organisms called amoebae- which could lead to a better understanding of how bacteria survive and help efforts to prevent the spread of infection.

14 Nov 2017

Monoclonal antibody effectively blocks development of graft-versus-host disease, research shows

Newly published research provides preclinical proof-of-concept for the ability of PRO 140, a humanized anti-CCR5 monoclonal antibody under development by CytoDyn Inc., to effectively block the development of graft-versus-host disease (GvHD), a potentially lethal complication of bone marrow stem cell (BMSC) transplantation.

14 Nov 2017

New drug shows promise in mouse model of autism disorder

Scientists have performed a successful test of a possible new drug in a mouse model of an autism disorder. The candidate drug, called NitroSynapsin, largely corrected electrical, behavioral and brain abnormalities in the mice.

14 Nov 2017

Medical Science News

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Study identifies molecular pathway critical to development of fibrosis

Researchers discover new way to target cancer without destroying healthy T-cells

Researchers test new vaccination strategy against HIV-related SIV in monkeys

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

Researchers find that tiny brain region plays key role in social memory formation

Nanowires could be potential drug delivery tools for neurodegenerative diseases

Eating nuts on a regular basis strengthens brainwave frequencies, study finds

Changes in multiple different genes drive world's most deadly forms of lung cancer

WFIRM-led project aims to study health risks astronauts face from exposure to space radiation

UCR-led research discovers that human protein could be used to treat sepsis

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Study provides new insights into basis for responsiveness of testicular cancer to chemotherapy

Chronic preconception exposure to genistein may adversely affect female fertility, mice study finds

Breakthrough discovery could radically change approach to treating Klebsiella infections

Research shows how food poisoning bacteria can multiply and spread inside micro-organisms

Monoclonal antibody effectively blocks development of graft-versus-host disease, research shows

New drug shows promise in mouse model of autism disorder

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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