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Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

Experimental ‘golden’ potato could hold power to prevent disease in developing nations

An experimental "golden" potato could hold the power to prevent disease and death in developing countries where residents rely heavily upon the starchy food for sustenance, new research suggests.

9 Nov 2017

Researchers catch killer cells red-handed in the act of microbial murder

Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been able to evade killer cells. This has caused researchers to become interested in finding out the exact mechanism that killer cells use to destroy bacterial invaders.

9 Nov 2017

Video provides new look at natural process of platelet-driven blood clot contraction

The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers from the Perelman School of Medicine at the University of Pennsylvania a new look at a natural process that is part of blood clotting.

9 Nov 2017

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

The Center for Applied NanoBioscience and Medicine is doing its part to protect the health of astronauts on long-duration missions, including NASA's Journey to Mars.

9 Nov 2017

Antiviral drug selectively targets the most aggressive viruses, research says

An antiviral drug that inhibits a virus' replication machinery selectively targets the most aggressive viruses, according to new research that looked at the infection of individual cells by a virus and the consequence of antiviral intervention.

9 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Research suggests link between heart function and brain region critical for memory processing

Research by a team of Vanderbilt University Medical Center scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer's pathology first begins.

9 Nov 2017

Injection of nanoparticles could divert immune cells that cause inflammation

A surprise finding suggests that an injection of nanoparticles may be able to help fight the immune system when it goes haywire, researchers at the University of Michigan have shown. The nanoparticles divert immune cells that cause inflammation away from an injury site.

9 Nov 2017

Scientists uncover mechanism that prevents tumor growth in melanoma

Natural Killer (NK) cells, lymphocytes of the innate immune system with strong cytotoxic activity, play a major role in the immune response against tumors.

8 Nov 2017

Researchers discover mechanism behind skin inflammation in eczema

Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema. Toxin-producing bacteria on the surface of our skin induces a protein that causes our own cells to react and cause inflammation.

8 Nov 2017

Scientists uncover previously unknown mechanism to combat influenza A virus

Just as flu season swings into full gear, researchers from the University of Colorado Boulder and University of Texas at Austin have uncovered a previously unknown mechanism by which the human immune system tries to battle the influenza A virus.

8 Nov 2017

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside cancer cells in laboratory cultures.

8 Nov 2017

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that's because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death.

8 Nov 2017

Endurance training can be helpful in dealing with muscle inflammation

Endurance training can actually be helpful in dealing with muscle inflammation, according to a new paper co-written by faculty at Binghamton University, State University of New York, and Karolinska Institutet and Karolinska University Hospital in Stockholm, Sweden.

8 Nov 2017

Individual neurons slow down when we are sleep deprived, study finds

It has been established that sleep deprivation slows down our reaction time, but it has been unclear exactly how the lack of sleep affects brain activity and subsequent behavior.

8 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

DGIST's research team led by Dr. Yun-Il Lee in Well-Aging Research Center has identified a new mechanism of inhibition of dopaminergic neuronal apoptosis and suggested the possibility of preventing and treating Parkinson's disease.

8 Nov 2017

New model could provide understanding of how HIV infection damages the brain

HIV infects certain cells in the brain called microglia, and infected microglia release toxic and inflammatory molecules that can impair or kill surrounding neurons.

8 Nov 2017

Medical Science News

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

3D cultured spheroids could drive precision treatment for ovarian cancer

Experimental ‘golden’ potato could hold power to prevent disease in developing nations

Researchers catch killer cells red-handed in the act of microbial murder

Video provides new look at natural process of platelet-driven blood clot contraction

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

Antiviral drug selectively targets the most aggressive viruses, research says

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

Research suggests link between heart function and brain region critical for memory processing

Injection of nanoparticles could divert immune cells that cause inflammation

Scientists uncover mechanism that prevents tumor growth in melanoma

Researchers discover mechanism behind skin inflammation in eczema

Scientists uncover previously unknown mechanism to combat influenza A virus

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Endurance training can be helpful in dealing with muscle inflammation

Individual neurons slow down when we are sleep deprived, study finds

Early intervention may be crucial to successful treatment of Friedreich's ataxia

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

New model could provide understanding of how HIV infection damages the brain

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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