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Scientists use nanoparticles to fight Mucoviscidosis

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.

15 Dec 2017

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level.

15 Dec 2017

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Microscopes enhanced with artificial intelligence could help clinical microbiologists diagnose potentially deadly blood infections and improve patients' odds of survival, according to microbiologists at Beth Israel Deaconess Medical Center

15 Dec 2017

Researchers uncover THOR gene involved in cancer development

It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer too.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Researchers have glimpsed how the toxic protein clusters that are associated with Parkinson's Disease disrupt the membranes of healthy brain cells, creating defects in the cell walls and eventually causing a series of events that induce neuronal death.

15 Dec 2017

Aging brain's failure to coordinate deep-sleep brainwaves makes older adults forget

Like swinging a tennis racket during a ball toss to serve an ace, slow and speedy brainwaves during deep sleep must sync up at exactly the right moment to hit the save button on new memories, according to new UC Berkeley research.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Extracellular vesicles can be used to effectively delay progression of kidney damage

Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with a type of chronic kidney disease.

15 Dec 2017

Rare gene mutation gives rise to low sensitivity to pain

Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by conditions such as lower back pain and osteoarthritis is one of the most prominent causes of disability worldwide, as assessed by the Global Burden of Disease reviews.

15 Dec 2017

A daily cup of hot tea may lower glaucoma risk

According to a small study published online yesterday in the British Journal of Ophthalmology, drinking at least one cup of hot tea daily may be associated with a considerably lower risk of contracting glaucoma, a serious eye condition.

15 Dec 2017

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome.

15 Dec 2017

Porvair and Suzhou Tianlong Bio to develop epigenetic analysis technologies

Porvair Sciences are teaming up with Suzhou Tianlong Bio Technology Co Ltd (China), together with Swansea University and Xi'an Jiaotong University in a collaborative project entitled, "Automating & Stratification of Epigenetics in Healthcare" that is part of the Innovate UK / Jiangsu Industrial Challenge Programme.

From Chromatrap® - Porvair Sciences Ltd 15 Dec 2017

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas.

15 Dec 2017

Scientists create atomic scale map that tracks how brain signals connect to neurons

Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic physics of the chemical's pathway, as well as the speed of nerve cell communications.

15 Dec 2017

Researchers team up to identify vulnerabilities of lethal parasite

An estimated 100 million people around the world are infected with Strongyloides stercoralis, a parasitic nematode, yet it's likely that many don't know it.

15 Dec 2017

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

A new study led by scientists at the University of Southampton has found that inherited variation in a particular gene may be to blame for the lower survival rate of patients diagnosed with early-onset breast cancer.

14 Dec 2017

Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics

Cancer molecular testing can drive clinical decision making and help a clinician determine if a patient is a good candidate for a targeted therapeutic drug.

14 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

Scientists unravel mystery of how immune cells remember infections decades later

A perplexing question in immunology has been, how do immune cells remember an infection or a vaccination so that they can spring into action decades later? Research led by scientists at the University of California, Berkeley, in collaboration with investigators at Emory University, has found an answer: A small pool of the same immune cells that responded to the original invasion remain alive for years, developing unique features that keep them primed and waiting for the same microbe to re-invade the body.

14 Dec 2017

Medical Science News

Scientists use nanoparticles to fight Mucoviscidosis

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Researchers uncover THOR gene involved in cancer development

Researchers examine human mutations' impact on therapeutic effect of medicine

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Aging brain's failure to coordinate deep-sleep brainwaves makes older adults forget

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Extracellular vesicles can be used to effectively delay progression of kidney damage

Rare gene mutation gives rise to low sensitivity to pain

A daily cup of hot tea may lower glaucoma risk

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Porvair and Suzhou Tianlong Bio to develop epigenetic analysis technologies

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Scientists create atomic scale map that tracks how brain signals connect to neurons

Researchers team up to identify vulnerabilities of lethal parasite

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

Scientists unravel mystery of how immune cells remember infections decades later

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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