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Ottawa researchers use viruses to target and destroy HIV

While Ottawa researchers are known for their work on cancer-fighting viruses, one team is applying these viruses to a new target: HIV.

19 Dec 2017

Mutational patterns could identify breast cancer patients most likely to respond to platinum-based chemotherapy

The presence in advanced breast cancer of mutational signatures characteristic of homologous recombination deficiency (HRD) was associated with improved clinical outcomes to treatment with platinum-based chemotherapy.

19 Dec 2017

TSRI scientists uncover new insights into regulatory network behind axon termination

All things must come to an end. This is particularly true for neurons, especially the extensions called axons that transmit electrochemical signals to other nerve cells. Without controlled termination of individual neuron growth, the efficient and accurate construction of a nervous system is in serious jeopardy.

19 Dec 2017

Study investigates how brain lesions can contribute to criminal behavior

New research published in the Proceedings of the National Academy of Sciences indicates that lesions to brain areas in individuals exhibiting criminal behavior all fall within a particular brain network involved in moral decision-making.

18 Dec 2017

New device uses fast-moving fluids to insert conductive carbon nanotube fibers into the brain

Rice University researchers have invented a device that uses fast-moving fluids to insert flexible, conductive carbon nanotube fibers into the brain, where they can help record the actions of neurons.

18 Dec 2017

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

By encapsulating bilirubin within tiny nanoparticles, researchers from North Carolina State University and the Ohio State University have improved the survival rates of pancreatic islet cells in vitro in a low-oxygen environment.

18 Dec 2017

EPFL scientists create gold nanoparticles to combat all viruses

HIV, dengue, papillomavirus, herpes and Ebola - these are just some of the many viruses that kill millions of people every year, mostly children in developing countries. While drugs can be used against some viruses, there is currently no broad-spectrum treatment that is effective against several at the same time, in the same way that broad-spectrum antibiotics fight a range of bacteria.

18 Dec 2017

Pitt researchers win NIH BRAIN award to enhance sensory feedback of prosthetic devices

Our tactile senses keep us aware of our environment and are essential for the execution of natural movement. Though there have been many advances in modern prosthetic devices, the loss of sensory feedback remains an issue, and many amputees struggle with everyday movement.

18 Dec 2017

Researchers identify novel mechanism that protects from brain tumor

A group of researchers at the Spanish National Cancer Research Centre have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 promoted glioma growth, by upregulating EGFR expression.

18 Dec 2017

Researchers find transient effects of food preservative on gut microbiome

Antimicrobial compounds added to preserve food during storage are believed to be benign and non-toxic to the consumer, but there is "a critical scientific gap in understanding the potential interactions" they may have with the hundreds of species of microbes in our intestines, say David Sela, a nutritional microbiologist at the University of Massachusetts Amherst, and colleagues.

18 Dec 2017

Moderate exercise reduces progression of Marfan syndrome symptoms in mice

Regular physical activity is a common therapy for people with cardiovascular problems, but not recommended to those with Marfan syndrome, a rare disease of the connective tissue, but mainly affecting the cardiovascular system.

18 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Many breast cancer patients do not feel fully informed about their treatment options, say researchers

A research team in the U.S. has found that most women who undergo breast cancer operations do not feel fully informed about their treatment options when they decide on which procedure to undergo.

18 Dec 2017

A guide to Severe Combined Immunodeficiency Disease, review released

A new review published today in the Canadian Medical Association Journal provides guidance on Severe Combined Immunodeficiency Disease (SCID), a deadly and rare disease that is potentially curable if detected early.

18 Dec 2017

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Mature cells also play role in initiating cancer, study suggests

Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells also play a key role in initiating cancer - a finding that could upend the way scientists think about the origin of the disease.

18 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Study reveals biology behind why muscle stem cells respond differently to aging or injury

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute describes the biology behind why muscle stem cells respond differently to aging or injury.

15 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

Medical Science News

Ottawa researchers use viruses to target and destroy HIV

Mutational patterns could identify breast cancer patients most likely to respond to platinum-based chemotherapy

TSRI scientists uncover new insights into regulatory network behind axon termination

Study investigates how brain lesions can contribute to criminal behavior

New device uses fast-moving fluids to insert conductive carbon nanotube fibers into the brain

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

EPFL scientists create gold nanoparticles to combat all viruses

Pitt researchers win NIH BRAIN award to enhance sensory feedback of prosthetic devices

Researchers identify novel mechanism that protects from brain tumor

Researchers find transient effects of food preservative on gut microbiome

Moderate exercise reduces progression of Marfan syndrome symptoms in mice

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Many breast cancer patients do not feel fully informed about their treatment options, say researchers

A guide to Severe Combined Immunodeficiency Disease, review released

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Mature cells also play role in initiating cancer, study suggests

Excessive copper in diabetes impedes ability to make new blood vessels

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Study reveals biology behind why muscle stem cells respond differently to aging or injury

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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